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New Delhi, Jan 06 (ANI): Researchers have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria, a potentially deadly infection associated with the use of antibiotics. The finding of the study was published in the journal of Proceedings of the National Academy of Sciences.

Researchers at the University of Maryland School of Medicine and their colleagues used cryo-electron microscopy, X-ray crystallography and other biophysical methods to identify the microscopic structures of the bacteria. The researchers mapped out the delivery and binding components of the toxin, which could pave the way for new drugs to neutralize it.

"We identified two structures that help explain the molecular underpinnings of C. difficile toxicity," said study co-author David Weber, Ph.D., a Professor of Biochemistry and Molecular Biology and Director of the Center for Biomolecular Therapeutics at UMSOM.

"These structures will be important for targeting th

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Study focuses on key structure of C. difficle bacteria that could lead to future treatments - Business Standard