Postdoctoral Positions in Inflammatory Bowel Diseases and Tumor Immunology

Two postdoctoral training positions are available in the laboratory of Hans-Christian Reinecker MD, in the Department of Internal Medicine, the Division of Digestive and Liver Diseases and Division of Immunology at UT Southwestern Medical Center to study the role of genetic variants associated with inflammatory bowel diseases on mechanisms of inflammation, tumorigenesis and anti-microbial host defenses. Focus is on new mechanisms of innate immune recognition for viral and bacterial pathogens and control of dendritic cells, macrophages and T cells. Our laboratory offers opportunities in these projects:

1. Target intracellular microtubule based microbial pattern recognition to control disease mechanisms of Inflammatory Bowel Diseases.2. Control of adaptive host-defenses by Schlafen family proteins.3. Controlling innate and adaptive immune responses by Sensor Stimulator of Interferon Genes (STING) mediated microbial recognition.4. Developing strategies to induce anti-tumor immunity for cancer immunotherapy.

Candidates must hold a Ph.D. and/or M.D. Degree. Experience in Immunology, Oncology or Microbiology in addition to a solid foundation in molecular and cell biology is required. Prior experiences in protein mutagenesis, gene targeting approaches or biochemistry is preferred. Prior work leading to publication in peer-reviewed journals is recommended.

Information on our postdoctoral training program and benefits can be found in our Postdoc Handbook or at http://www.utsouthwestern.edu/postdocs.

Interested individuals should send a CV, statement of interests, and a list of three references to:

Hans-Christian Reinecker, M.D.UT Southwestern Medical Center5323 Harry Hines Blvd.Dallas, TX 75390-9151Hans-Christian.Reinecker@UTSouthwestern.edu

UT Southwestern Medical Center is an Affirmative Action/Equal Opportunity Employer. Women, minorities, veterans and individuals with disabilities are encouraged to apply.

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