Cellular membranes are key to the compartmentalization of cellular processes and serve as platforms for the assembly of protein signaling complexes. Most human diseases can be traced to defects in signal generation and decoding caused by altered interaction of proteins with cellular membranes.

The unique lipid composition of different membranes defines organelle identity and is critical for proteinmembrane interactions. How cells generate and maintain the specific lipid composition of their organelles against complex and highly dynamic vesicular transport pathways is a fundamental question at the intersection of lipid and cell biology. Moreover, nonvesicular lipid transfer and contact sites formed between various organelles, as well as transient spikes in signaling lipids, are critical for cell signaling and homeostasis.

The theme of this session is how to respond to these important questions, and the program features expert speakers covering a variety of exciting topics within this theme.

Keywords: lipid transfer proteins, membrane contact sites, lipid compartmentalization, lipid dynamics, cell signaling

Who should attend: both experts and novices who recognize that not all lipids are bad for your health and also people who are interested in proteins, as we understand that membranes without proteins and proteins without membranes would not support life

Theme song: "Come Together" by the Beatles, the first allusion to the importance of organelle contact sites

This session is powered by Palmolive chasing lipids since 1898.

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Join the conversation on how cells talk to themselves and to each other - American Society for Biochemistry and Molecular Biology