ONE of Grey's Anatomy biggest star's today looked unrecognisable as he showed off his new blonde hair transformation.

Fans were left shocked when Patrick Dempsey revealed his striking new locks.

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Known by fans as 'Doctor McDreamy', the actor played Derek Shepherd on Grey's Anatomy for 16 years until 2021.

But this weekend he showed off his new look while appearing at Disney's D23 Expo in California.

Instead of his signature salt-and-pepper coif, the hunky star debuted a shock of bleach blond hair.

While Patrick might be best known for his work on ABC's hit medical drama Grey's Anatomy, he's also reprising his role from a beloved Disney film.

Patrick will take to the screen alongside Amy Adams as their popular characters from Disney's Enchanted in the film's sequel, Disenchanted.

The first trailer for the film, set for release in November on Disney+, was revealed during D23 Expo.

Disenchanted will follow Giselle (Amy), the animated princess who fell in love in New York City in the first movie, as she and Robert (Patrick) move to the suburbs.

James Marsden and Idina Menzel are also reprising their roles for the fantasy film.

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"To work with everybody again after 14 years is just really exciting," Patrick toldVarietyin April 2021.

"We need some escapism right now. We need those romantic comedies and those musicals to get people out of the doldrums that we're in."

Before finding fame on Grey's Anatomy, Patrick had early success on the big screen starring in a number of 80s films including Can't Buy Me Love (1987), and Loverboy (1989).

In 2002 he also had the lead role alongside Reese Witherspoon in Sweet Home Alabama, which was a surprise box office hit.

Patrick is married to wife Jillian Fink, and the couple share three children.

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