In the same interview with The Wrap about the "Pick Yourself Up" episode from Season 19 of "Grey's Anatomy," director/actor Kevin McKidd talked about the difficulty of pulling off a single take, no-cut opening scene resolving the previous episode's dramatic cliffhanger. McKidd said, "It was such an immediate, visceral moment to try and save this pregnant woman and her baby after being run over. It seemed like the perfect moment to do this whole thing as one, very immediate shot."

According to McKidd, he had been pitching the writers of the show the idea of doing an episode in a single take for years. While it had never come to pass, McKidd saw an opportunity when reading the script for this episode. "I read this episode and this scene was so immediate. It just screamed at me that this whole first act could be done in one shot. We've never done that on our show." He pitched it to the showrunner, and they were off to make this opening scene happen.

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This Grey's Anatomy Season 19 Scene Was The Most Difficult Of ... - Looper