Gobinath AR, Choleris E, Galea LA. Sex, hormones, and genotype interact to influence psychiatric disease, treatment, and behavioral research. J Neurosci Res. 2017;95:5064.
Article CAS PubMed Google Scholar
Riecher-Rssler A. Sex and gender differences in mental disorders. Lancet Psychiatry. 2017;4:89.
Article PubMed Google Scholar
Marcus SM, Kerber KB, Rush AJ, Wisniewski SR, Nierenberg A, Balasubramani GK, et al. Sex differences in depression symptoms in treatment-seeking adults: confirmatory analyses from the sequenced treatment alternatives to relieve depression study. Compr Psychiatry. 2008;49:23846.
Article PubMed PubMed Central Google Scholar
Schuch JJ, Roest AM, Nolen WA, Penninx BW, de Jonge P. Gender differences in major depressive disorder: results from the Netherlands study of depression and anxiety. J Affect Disord. 2014;156:15663.
Article PubMed Google Scholar
Hfner H, Maurer K, Lffler W, Riecher-Rssler A. The influence of age and sex on the onset and early course of schizophrenia. Br J Psychiatry. 1993;162:806.
Article PubMed Google Scholar
Ochoa S, Usall J, Cobo J, Labad X, Kulkarni J. Gender differences in schizophrenia and first-episode psychosis: a comprehensive literature review. Schizophr Res Treat. 2012;2012:916198.
Google Scholar
Goldstein JM, Link BG. Gender and the expression of schizophrenia. J Psychiatr Res. 1988;22:14155.
Article CAS PubMed Google Scholar
Randall CL, Roberts JS, Del Boca FK, Carroll KM, Connors GJ, Mattson ME. Telescoping of landmark events associated with drinking: a gender comparison. J Stud Alcohol. 1999;60:25260.
Article CAS PubMed Google Scholar
Diehl A, Croissant B, Batra A, Mundle G, Nakovics H, Mann K. Alcoholism in women: is it different in onset and outcome compared to men? Eur Arch Psychiatry Clin Neurosci. 2007;257:34451.
Article PubMed Google Scholar
Kouneiher F, Charron S, Koechlin E. Motivation and cognitive control in the human prefrontal cortex. Nat Neurosci. 2009;12:93945.
Article CAS PubMed Google Scholar
Schlaepfer TE, Harris GJ, Tien AY, Peng L, Lee S, Pearlson GD. Structural differences in the cerebral cortex of healthy female and male subjects: a magnetic resonance imaging study. Psychiatry Res. 1995;61:12935.
Article CAS PubMed Google Scholar
Gur RC, Turetsky BI, Matsui M, Yan M, Bilker W, Hughett P, et al. Sex differences in brain gray and white matter in healthy young adults: correlations with cognitive performance. J Neurosci. 1999;19:406572.
Article CAS PubMed PubMed Central Google Scholar
Goldstein JM, Seidman LJ, Horton NJ, Makris N, Kennedy DN, Caviness VS Jr, et al. Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cereb Cortex. 2001;11:4907.
Article CAS PubMed Google Scholar
Knouse MC, McGrath AG, Deutschmann AU, Rich MT, Zallar LJ, Rajadhyaksha AM, et al. Sex differences in the medial prefrontal cortical glutamate system. Biol Sex Differ. 2022;13:66.
Article CAS PubMed PubMed Central Google Scholar
Gabbott PL, Warner TA, Jays PR, Salway P, Busby SJ. Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. J Comp Neurol. 2005;492:14577.
Article PubMed Google Scholar
Sesack SR, Deutch AY, Roth RH, Bunney BS. Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: an anterograde tract-tracing study with Phaseolus vulgaris leucoagglutinin. J Comp Neurol. 1989;290:21342.
Article CAS PubMed Google Scholar
Freund TF, Katona I. Perisomatic inhibition. Neuron. 2007;56:3342.
Article CAS PubMed Google Scholar
Tremblay R, Lee S, Rudy B. GABAergic Interneurons in the neocortex: from cellular properties to circuits. Neuron. 2016;91:26092.
Article CAS PubMed PubMed Central Google Scholar
Fish KN, Joffe ME. Targeting prefrontal cortex GABAergic microcircuits for the treatment of alcohol use disorder. Front Synaptic Neurosci. 2022;14:936911.
Article CAS PubMed PubMed Central Google Scholar
Marin O. Interneuron dysfunction in psychiatric disorders. Nat Rev Neurosci. 2012;13:10720.
Article CAS PubMed Google Scholar
Ferguson BR, Gao WJ. PV interneurons: critical regulators of E/I balance for prefrontal cortex-dependent behavior and psychiatric disorders. Front Neural Circuits. 2018;12:37.
Article PubMed PubMed Central Google Scholar
Chung DW, Fish KN, Lewis DA. Pathological basis for deficient excitatory drive to cortical parvalbumin interneurons in schizophrenia. Am J Psychiatry. 2016;173:113139.
Article PubMed PubMed Central Google Scholar
Perlman G, Tanti A, Mechawar N. Parvalbumin interneuron alterations in stress-related mood disorders: a systematic review. Neurobiol Stress. 2021;15:100380.
Article CAS PubMed PubMed Central Google Scholar
Du X, Serena K, Hwang WJ, Grech AM, Wu YWC, Schroeder A, et al. Prefrontal cortical parvalbumin and somatostatin expression and cell density increase during adolescence and are modified by BDNF and sex. Mol Cell Neurosci. 2018;88:17788.
Article CAS PubMed Google Scholar
Goodwill HL, Manzano-Nieves G, LaChance P, Teramoto S, Lin S, Lopez C, et al. Early life stress drives sex-selective impairment in reversal learning by affecting parvalbumin interneurons in orbitofrontal cortex of mice. Cell Rep. 2018;25:2299307.e4.
Article CAS PubMed PubMed Central Google Scholar
Holland FH, Ganguly P, Potter DN, Chartoff EH, Brenhouse HC. Early life stress disrupts social behavior and prefrontal cortex parvalbumin interneurons at an earlier time-point in females than in males. Neurosci Lett. 2014;566:1316.
Article CAS PubMed PubMed Central Google Scholar
Page CE, Shepard R, Heslin K, Coutellier L. Prefrontal parvalbumin cells are sensitive to stress and mediate anxiety-related behaviors in female mice. Sci Rep. 2019;9:19772.
Article CAS PubMed PubMed Central Google Scholar
Joffe ME, Winder DG, Conn PJ. Contrasting sex-dependent adaptations to synaptic physiology and membrane properties of prefrontal cortex interneuron subtypes in a mouse model of binge drinking. Neuropharmacology. 2020;178:108126.
Article CAS PubMed PubMed Central Google Scholar
Maksymetz J, Byun NE, Luessen DJ, Li B, Barry RL, Gore JC, et al. mGlu(1) potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits. Cell Rep. 2021;37:109950.
Article CAS PubMed PubMed Central Google Scholar
Trantham-Davidson H, Burnett EJ, Gass JT, Lopez MF, Mulholland PJ, Centanni SW, et al. Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex. J Neurosci. 2014;34:370618.
Article CAS PubMed PubMed Central Google Scholar
Barnes SA, Pinto-Duarte A, Kappe A, Zembrzycki A, Metzler A, Mukamel EA, et al. Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders. Mol Psychiatry. 2015;20:116172.
Article CAS PubMed PubMed Central Google Scholar
Joffe M, Maksymetz J, Luschinger J, Dogra S, Ferranti A, Luessen D, et al. Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons. Neuron. 2022;110:10681083.e5.
Joffe ME, Centanni SW, Jaramillo AA, Winder DG, Conn PJ. Metabotropic glutamate receptors in alcohol use disorder: physiology, plasticity, and promising pharmacotherapies. ACS Chem Neurosci. 2018;9:2188204.
Article CAS PubMed Google Scholar
Niswender CM, Conn PJ. Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu Rev Pharm Toxicol. 2010;50:295322.
Article CAS Google Scholar
Conn PJ, Pin JP. Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharm Toxicol. 1997;37:20537.
Article CAS Google Scholar
Fabian CB, Seney ML, Joffe ME. Sex differences and hormonal regulation of metabotropic glutamate receptor synaptic plasticity. Int Rev Neurobiol. 2023;168:31147.
Article CAS PubMed Google Scholar
Tabatadze N, Huang G, May RM, Jain A, Woolley CS. Sex Differences in molecular signaling at inhibitory synapses in the hippocampus. J Neurosci. 2015;35:1125265.
Article CAS PubMed PubMed Central Google Scholar
Huang GZ, Woolley CS. Estradiol acutely suppresses inhibition in the hippocampus through a sex-specific endocannabinoid and mGluR-dependent mechanism. Neuron. 2012;74:8018.
Article CAS PubMed PubMed Central Google Scholar
Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, et al. A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005;3:e159.
Article PubMed PubMed Central Google Scholar
Kaiser T, Ting JT, Monteiro P, Feng G. Transgenic labeling of parvalbumin-expressing neurons with tdTomato. Neuroscience. 2016;321:23645.
Article CAS PubMed Google Scholar
Xu J, Zhu Y, Contractor A, Heinemann SF. mGluR5 has a critical role in inhibitory learning. J Neurosci. 2009;29:367684.
Article CAS PubMed PubMed Central Google Scholar
Straiker A, Mackie K. Depolarization-induced suppression of excitation in murine autaptic hippocampal neurones. J Physiol. 2005;569:50117.
Article CAS PubMed PubMed Central Google Scholar
Marcus DJ, Bedse G, Gaulden AD, Ryan JD, Kondev V, Winters ND, et al. Endocannabinoid signaling collapse mediates stress-induced amygdalo-cortical strengthening. Neuron. 2020;105:106276.e6.
Article CAS PubMed PubMed Central Google Scholar
Maksymetz J, Byun NE, Luessen DJ, Li B, Barry RL, Gore JC, Niswender CM, et al. mGlu1 potentiation enhances cortical somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits. Cell Rep. 2021;37:109950.
Article CAS PubMed PubMed Central Google Scholar
Thompson SM, Fabian CB, Ferranti AS, Joffe ME. Acute alcohol and chronic drinking bidirectionally regulate the excitability of prefrontal cortex vasoactive intestinal peptide interneurons. Neuropharmacology. 2023;238:109638.
Article CAS PubMed Google Scholar
Mannaioni G, Marino MJ, Valenti O, Traynelis SF, Conn PJ. Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function. J Neurosci. 2001;21:592534.
Article CAS PubMed PubMed Central Google Scholar
Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, et al. Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system. Neuropharmacology. 2018;128:30113.
Article PubMed Google Scholar
Gereau RWt, Conn PJ. Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CA1 pyramidal cell excitability. J Neurophysiol. 1995;74:1229.
Article Google Scholar
Wu S, Wright RA, Rockey PK, Burgett SG, Arnold JS, Rosteck PR Jr., et al. Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells. Brain Res Mol Brain Res. 1998;53:8897.
Article CAS PubMed Google Scholar
Ferranti AS, Johnson KA, Winder DG, Conn PJ, Joffe ME. Prefrontal cortex parvalbumin interneurons exhibit decreased excitability and potentiated synaptic strength after ethanol reward learning. Alcohol. 2022;101:1726.
Article PubMed PubMed Central Google Scholar
Markram H, Toledo-Rodriguez M, Wang Y, Gupta A, Silberberg G, Wu C. Interneurons of the neocortical inhibitory system. Nat Rev Neurosci. 2004;5:793807.
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