Before they achieved critical fame on Grey's Anatomy, these actors starred in several feature movies and hit films.

Today, Greys Anatomyhas one of the longest-running tv shows of all time. Created by Shonda Rhimes,the medical dramafocuses on its characters and the personal drama that they bring to each episode. There is also plenty of laughs, drama, intriguing storylines, and cleverly crafted dialogue that fans have thoroughly enjoyed too.

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As far as the cast goes, the show also boasts of one of the largest assemblies of on television. With over 200 main characters, it's not surprising if some of its cast look quite familiar. In some cases, these cast members have also appeared in some hit movies, including:

Before she ever landed the titular role on Greys Anatomy, Ellen Pompeo worked on a number of feature films early on in her career. Among them was this 2002 drama that also stars Dustin Hoffman, Susan Sarandon, and Jake Gyllenhaal.

In the movie, Pompeo and Gyllenhaal cross paths as Gyllenhaal mourns the death of his fianc. While recalling Pompeos audition for the movie, Gyllenhaal told the Los Angeles Times, And she blew the audition out of the water. Interestingly, the two also had a brief encounter shortly before they learned that they would be working on this movie together.

This 2002 movie is considered one of the best cat and mouse films today. Catch Me If You Can boasts of a cast that includes Tom Hanks, Leonardo DiCaprio, Amy Adams, Martin Sheen, and Christopher Walken. The movie also stars Pompeo. However,it's sort of one of those blink-and-you-miss-it appearances.

The actress appears briefly in a scene as a flight attendant, a role that Spielberg had offered to her. While speaking with Los Angeles Times, Pompeo recalled, And I graciously accepted. And screamed all the way home.

In this 2002 romantic comedy, Reese Witherspoon plays a New York City socialite who needs to return to Alabama to get a divorce from her estranged husband. In the movie, Patrick Dempsey plays Witherspoons ideal fianc while Josh Lucas plays the man she cant wait to divorce. In 2019, there was talk of a possible sequel.

While on Good Morning America, Lucas said theres a proposed storyline where Dempseys character is still in the picture. According to USA Today, Witherspoon has said she would happily make Sweet Home Alabama 2.

In this 2007 comedy, Greys Dempsey plays a single father who meets a woman from a fairy tale world. Of his role, the actor admits that he found it to be both fun and challenging. Dempsey even told Cinema.com, There were times when I wanted to put the scrubs back on and go back to Greys Anatomy because I kept worrying that I was too serious or not funny enough.

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Interestingly, Dempseys leading lady was also supposed to be Witherspoon. The role eventually went to Amy Adams.

Sideways is a critically acclaimed film about two men who decide to make a trip to Californias wine country just before one of them gets married. In the movie, Greys Sandra Oh plays a single mom. While discussing the film, Oh told Entertainment Weekly, In Sideways, I have maybe 15, 20 lines. But because of the way the film is written, you never see anyone as a sidekick or a girlfriend.

Sideways went on to score several Oscar nods and an Oscar win for best-adapted screenplay. It is also known as one of Alexander Paynes best movies.

This 2010 movie centers on a dancer who is dealing with a multiple personality disorder. Frankie & Alice stars Halle Berry, Stellan Skarsgrd, Phylicia Rashad, and Greys Chandra Wilson. While discussing the movie withShock Ya!, Wilson revealed that she wanted to do the film because of the cast.

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The actress even jokingly remarked, So in a way, it didnt matter what the project was going to be. Meanwhile, Wilson also revealed that she only had a few days to shoot her scenes for the movie because of her Greys schedule.

In a similar structure to Love Actually,Valentine's Dayfollowed the lives of several characters. One of the stories sees Sean (Eric Dane), who is a closeted gay football star attempt to save his relationship with his boyfriend (Bradley Cooper) after tensions between them become too much.

Dane wasn't the onlyGrey'sstar to feature in the movie either.Patrick Dempsey also appears, playing a cardiothoracic surgeon, who is also the boyfriend of Jennifer Garner's character. In an ironic twist, he is also revealed to be married.

The 2009 sequel stars Chris Carmack as a man who uses his power to time travel and solve the mystery surrounding the death of his girlfriend.

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Aside from playing the lead role in the movie, Carmack also contributed behind the scenes, specifically when it came to some of the background music. I was working with director Seth Grossman and he had mentioned he wanted to put some bluesy type tunes in the background of some of the bar scenes, Carmack told Media Mikes. He asked if I had any music he could use and I told him I did

The November Man stars Pierce Brosnan as a former CIA agent, who takes on a personal mission and finds himself going up against a former pupil. The movie also stars Greys Anatomys Caterina Scorsone as Celia, who plays a CIA official.

The November Man came out around the time that Scorsones stint in the Greys spinoff, Private Practice, had ended. As interesting as the premise of the movie may seem, The November Man received lackluster reviews from critics. There is consensus that the movie just utilizes a lot of spy action-thriller clichs.

In this comedy, Ben Stiller plays a security guard who works at a museum where figures come alive at night. The movie also stars Kim Raver as Stillers ex-wife. Around the time that Raver was working on the movie, she was yet to join the cast of Greys. That said, she was starring in the series 24.

Night at the Museum may be seen as a great family movie, but many say that it also features one of the worst graphics, especially when it comes to the mummies. However, as long as kids are watching, many fans dont mind that Rami Malek is playing a not-so-scary mummy.

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