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POC-PSC war: Anatomy of a dispute – Inquirer.net

The bone of contention cant get any clearer than this for the feuding Philippine Olympic Committee (POC) and the governments Philippine Sports Commission (PSC):

Would you let an old partner who pays for your rent and utilities and provides your children pocket money and free training have a say in how you fix your own house?

The POC says the PSC cant, citing the evils of government intervention in sports.

READ:Peping accuses Fernandez of game-fixing during PBA days

The PSC claims it has the right to make demands, short of actual intervention, since the POC and its NSAs (national sports associations) draw succor from the government.

The dispute wouldnt have come to this if longtime POC president Jose Cojuangco Jr., the man ultimately responsible for the countrys miserable performances in international multisport competitions, had ignored social media snipings and refrained from accusing the PSC of interference in POC affairs.

POC President Peping Cojuangco. Photo by Tristan Tamayo/INQUIRER.net

The octogenarian Cojuangco went one step further: He denounced PSC Commissioner Ramon Fernandez, a staunch critic, as a game-fixer and said he had proof the former basketball star was engaged in point shaving during his heyday.

Cojuangcos verbal assault made PSC Chair William Butch Ramirez livid. He advised the POC to find new sources of funds if it didnt want the agency to meddle in its affairs.

READ:PSC-POC rift a catalyst for change

After all, Ramirez said, several NSAs still have to liquidated cash advances amounting to P150 million.

We respect their independence, said the PSC chief. But if they dont want us to meddle, then stop asking funds from us. The law says that we can exercise visitorial and supervisory powers to make sure that the peoples money is spent well.

The verbal skirmish boils down to a clash of principles.

READ:POC, PSC urged to settle differences for PH athletes

Were in charge of training our national athletes and the PSCs role is to fund everything the athletes need, Cojuangco insisted.

Fernandez said he would file a libel case against Cojuangco in Cebu City after consulting his lawyers.

PSC Commissioner Mon Fernandez. Photo by Tristan Tamayo/INQUIRER.net

He called me a game-fixer when he should have called me a team-fixer because I helped my teams win championships, said the four-time PBA MVP, a member of 19 champion teams in the pro league.

Cojuangco said Fernandez started it all. He was critical of me from the very beginning, the 82-year-old former Tarlac congressman said. He even said they intend to take over the POC, that the PSC should run sports in the Philippines.

I dont want to talk [about Fernandezs alleged game fixing] anymore. But if they demand it, Ill tell them what I know.

READ:Official sees end of POC-PSC row; Fernandez not done with Peping yet

Fernandez has since resumed the offensive on social media. Last week he posted documents showing the POC had received P38 million from the government agency to fund the countrys hosting of the Asian Centennial Games Festival in 2014.

At first glance, nothing seemed irregular about the fund, until Fernandez claimed that the POC received tens of millions from the Olympic Council of Asia (OCA) specifically to spend for the festival, which was attended by national Olympic committee leaders from 43 countries.

He (Cojuangco) should return the money, said Fernandez.

Coming to Cojuangcos aid, POC secretary general Steve Hontiveros said all financial assistance from the PSC have been properly liquidated, complete with corresponding documents and receipts.

PSC chair William Ramirez. Tristan Tamayo/INQUIRER.net

Ramirez said Cojuangco should answer Fernandezs allegations squarely. After all, the documents emanated from the PSC, he pointed out.

Inspite of the conflict, our support to the athletes and coaches have been stronger and were committed to support them even beyond [the] 2020 [Tokyo Olympics].

Cojuangco and Ramirez go a long way. The two were just starting their first terms as heads of the two sports bodies in 2005 when they brought the Philippines to the pinnacle of success in the Southeast Asian Games. That was the only time the Filipino athletes won the coveted overall championship in the biennial meet.

READ:PSC assumes lead role in grassroots programs

When President Duterte came to power in July last year, Ramirez, the Davao City mayors most reliable sports manager, returned to his old post.

Ramirez said the dispute should not sidetrack the PSC from bringing sports to the countryside and strengthening the grassroots program ordered by Duterte. We dont have time to pick a fight, he said.

Cojuangco, meanwhile, said the row with the PSC might only distract the athletes. Were busy preparing for the Southeast Asian Games and the Asian Indoor and Martial Arts Games. We need to focus, he said.

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POC-PSC war: Anatomy of a dispute - Inquirer.net

Anatomy of a Painting: Artist Tim Jaeger looks at his ‘CS No. 24’ – Sarasota Herald-Tribune

By Marty FugateCorrespondent

The roosters crow violates local noise ordinances. To be fair, the iconic, barnyard fowl has something to crow about. Look, and youll see the beast everywhere from folklore to breakfast cereal, cartoons and the Chinese calendar. (2017 is the Year Of The Fire Rooster, actually.)

The rooster also roosts in Tim Jaegers paintings. Although the Sarasota-based artist tackles a variety of human and animal subjects, hes best known for this exuberant bird. Jaegers latest rooster-related piece, CS No. 24, is destined for the Anderson OBrien Fine Art gallery in Omaha. This multimedia image comprises acrylics, oil pastels, fabric and stalks. At our request, Jaeger kept this rough diary as he put the image together.

Getting Started: The first step is the hardest. As Robert Rauschenberg once said, An empty canvas is full. Theres infinite possibility; I can go in any direction, and nothing tells me which way to go. Confronting a blank canvas always fills me with anxiety and intimidation the same nervous feelings I had when I first started painting. The only way to get past this is to simply start making marks.

Turn Back or Keep Going: Within the first ten minutes, I can usually feel whether a painting will be successful or not. I say, feel, because this knowledge comes from the gut, not from intellectual analysis or an art theory book. If my gut tells me the piece is working, I keep going. If I know its a false start, I stop.

Rough Outlines: If Im confident in my first brush strokes, Ill follow up by painting the rough contours of the figure those few basic lines that define the form. Its a literal outline, but also an outline of where I want to go with the work: a visual means of writing notes to myself. Its my way of knowing where things are and should be as I make further progress. Ill constantly refer to these marks as I keep going, for as long as I can see them. This layer is really the foundational level. By the time Im through, Ill wind up painting over most of it.

Over-painting: I like to start with darker colors; this creates the illusion of depth when I paint lighter colors on top. Ill keep on doing this, adding lighter and lighter colors, one layer after another. Up to the very end, Im working with opaque acrylics, and its a slow process. Normally, it takes me anywhere from two to four weeks to create a painting. Ill usually work on four to five paintings at a time.

Finishing touches: The last week of painting is probably my favorite. I know Im over the hump and the end is in sight. At this point, Ill cease adding opaque colors. Ill concentrate on glazes and varnishes. When my gut tells me the painting is complete, Ill put on the last brush stroke and thats it.

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Anatomy of a Painting: Artist Tim Jaeger looks at his 'CS No. 24' - Sarasota Herald-Tribune

The Dynamic Brain Drawings of the Father of Modern Neuroscience – Hyperallergic

The labyrinth of the inner ear (courtesy Instituto Cajal del Consjo Superior de Investigaciones Cientficas, Madrid, 2017 CSIC)

Santiago Ramn y Cajalwanted to be an artistand photographer, but his physician father encouraged him to go into the medical profession. Even working in neuroscience, the Spaniards interest in visual art ended up proving essential, andhis illustrations continue to appear in textbooks and medical literature.The Beautiful Brain: The Drawings of Santiago Ramn y Cajal,out now from Abrams Books, accompanies atraveling exhibitionthat opened this January atthe Weisman Art Museum at the University of Minnesota and was organized with the Cajal Institute in Madrid, Spain. Both the book and the showconcentrate on 80 visualizations of the human brain by Cajal, often ordained the father of modern neuroscience.

Cajals drawings depict everythingfrom the cerebral cortex to the hippocampus, and some have not been previously published outside of his scholarly papers. The scientist, who died in 1934, wrote in his autobiography:

Like the entomologist in pursuit of brightly colored butterflies, my attention hunted, in the flower garden of the gray matter [the cerebral cortex], cells with delicate and elegant forms, the mysterious butterflies of the soul, the beatingof whose wings may someday who knows? clarify the secret of mental life.

Cajal was awarded the Nobel Prize in 1906, yethe remainsobscure compared to 19th-century scientists such asCharles Darwin andLouis Pasteur. Neuroscientist Larry W. Swanson writes in a book essay that this may bebecause there is no simple means to encapsulate how Cajal and his contemporaries explained and illustrated the workings of the brain as a biological network in an entirely new way, a way that remains foundational to neuroscientists today. Indeed, not every viewer will understand how he was able to discern the information flow of neurons in the retina just by studyingspecimens through amicroscope, but with theirclean lines and directional indications, the illustrationsarevisually striking.

That Cajals drawings remain living documents a century after they were created is at least partly owing to this vitality, which draws on fantasy and the imagination more than we might expect in scientific project, write Lyndel King and Eric Himmel in a collaborative book essay. Cajals forms are drawn with clarity, though never mechanically, and his line is confident and constantly moving: Dendrites and axons, the brains wiring, seem to pulse with life, twisting and turning and bulging and narrowing.

Over five decades, Cajal mademore than 2,900 drawings of the nervous system. His illustrations are so intricatethatits easy to forget he was working from dead tissue rather than a living organ. Decades later, when we can examine more accurate scans of the brain, his work stillconveys a prescient viewof itsinner workings. If the human individual resides anywhere in the body, its in this organ, and Cajals art gives humanity to anatomy while also portrayingitwith scientific precision.

The Beautiful Brain: The Drawings of Santiago Ramn y Cajalisout now from Abrams Books. The exhibition continues at the Weisman Art Museum (University of Minnesota, 333 E River Road, Minneapolis) throughMay 21.

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The Dynamic Brain Drawings of the Father of Modern Neuroscience - Hyperallergic

On Faith: Back on track – Lake County News Chronicle

According the Centers for Disease Control and Prevention, depression and anxiety are major causes for illness and death. Maybe you're feeling a bit down this time of year. If so, you are not alone. A nationwide survey indicated that 6 to 8 percent of Minnesotans reported being depressed. Cold winters and long nights do not help matters. Those who study human behavior confirm the idea that if we do not take action, we will tend to stay "down in the dumps." Getting down occasionally is a normal human experience. Staying down is not.

In abnormal cases of depression, the individual wants to feel this way and tends to hold others responsible for it. He believes other people owe him special attention and sympathy. He does not know what has caused him to feel this way and fears that something worse may happen. This individual, with full support of family and friends, should get help right away.

In a more typical case of the "doldrums," we acknowledge that it is not good to be like this, and we do not want it to continue. We feel guilty about being depressed and are willing to admit that it is our own fault. We are not alone in this. Even people in the Bible suffered in this way. One person that stands out to me is the prophet Elijah who appears to be experiencing a temporary state of depression in I Kings Chapter 19. In that passage, three responses to depression come to my mind.

First, do a self-inventory and try to identify the possible causes for our depression. In Elijah's case, he wanted his life to be over because he did not believe he was better than his ancestors (I Kings 19:4). This was pride on his part. Other causes for depression might be selfish anger, refusal to carry out our responsibilities, or running from our problems. Honestly acknowledging our own sinful behavior is the first step to getting right with God.

Next, allow your feelings to motivate you to see what really matters. In I Kings 19:1-7, God sent an angel to encourage Elijah to look at the big picture. God used this down time in Elijah's life to guide the thoughts of his wayward prophet toward the task at hand an upcoming journey that he needed to prepare for. God provided food and water to refresh him. Thus strengthened with physical nourishment, Elijah could respond to God's wisdom and encouragement.

Finally, choose to get back up and do what God wants you to do. In I Kings 19:8, Elijah "arose, and ate and drank, and went..." The depressed feelings were real, but thankfully, only temporary. When Elijah stopped making excuses for himself and started listening to God, his life dramatically improved. Elijah had failed to distinguish between what he wanted and what God wanted.

Getting what we want seldom makes us happy. Obeying what God wants is the right response. God wants us to make it our goal to be pleasing to him and useful to others. Being depressed and self-focused is never pleasing to God. Our designer did not create us to live that way. However, when we get our eyes off ourselves and focus on what's important, as Elijah did, God will restore us and get us back on track.

The Rev. Joe Whiting makes his home in Two Harbors with his wife, two sons, and a standard poodle. On Faith is a weekly column in the News-Chronicle written by area religious leaders.

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On Faith: Back on track - Lake County News Chronicle

Troy Reimink: ‘Buffy the Vampire Slayer’ helped me become less of a jerk – Traverse City Record Eagle

The worst cliche in pop culture is the suggestion that platonic friendship is just true love waiting to happen. I don't say worst only because it's lazy, which it is, but because it's a dangerous, false and cruel idea for entertainment to promote.

Chuck Klosterman, in his 2003 book "Sex, Drugs, and Cocoa Puffs," described this as the "When Harry Met Sally" problem, referring to the romantic comedy that "made it realistic to suspect your best friend may be your soul mate, and it made wanting such a scenario comfortably conventional."

Plenty of movies and shows before and since have validated the notion that a friend you happen to develop romantic feelings for is just a future lover who doesn't realize it yet. Almost every long-running television series featuring an opposite-sex friendship has at some point fallen back on the "let's hook them up" storyline. It makes sense you can't fill 11 seasons of "Friends" or "Cheers" without eventually pairing off some of the leads.

"Buffy the Vampire Slayer," the best and most important show ever created seriously, fight me on this had a clever way of handling the inevitable sexual tension between its lead female and male characters: it abstained.

Fans of the show last week celebrated the 20th anniversary of its premiere on the WB network. Plenty has been written in the media about this milestone, and there is a lot to say about the Joss Whedon series' formal inventiveness, its fierce feminist message, its powerful LGBT advocacy, its subversion of narrative tropes and its role in normalizing geek culture.

But what I remember most from the shows seven-year run is a warning about mixing friendship and more-than-friendship. In the finale of the first season, Xander (Nicholas Brendon) finally musters the courage to confess to his best friend Buffy (Sarah Michelle Gellar) that he loves her. He delivers a well-rehearsed speech asking her to a school dance, but she says no.

Buffy, taken aback by the unexpected advance, feels terrible about rejecting her friend. Xander, his pride wounded by the rebuke, says something mean and stomps off, leaving her hurt and confused even though she didnt do anything. Later in the episode, Xander recognizes that his friendship with Buffy, and all the demon-fighting they do together, is more important than his precious feelings and saves her from death at the hands of a vampire master, as one does.

Its a delicate handling of something almost everyone encounters, some of us more than others. An even better episode in the second season found Xander empowered by a misfired love spell that made him the object of lust for every girl in school, including his onetime friend-crush, Buffy, where he learns that getting what you think you want might actually be a nightmare.

The show should be mandatory viewing for every high-school student. If Id seen and internalized it when it originally aired, instead of when I fell into a Netflix rabbit hole at about age 30, I might have avoided years of dumb behavior.

For the longest time, I was one of those dudes who would always fail romantically, blame everyone but himself, then use the failure as an excuse to become embittered instead of addressing an underlying terror of intimacy. I was a Xander, which is to say, a jerk.

A Xander will complain about the friend zone as if its some dark corner of the Buffyverse to which all nice guys are banished. He'll will read an embarrassing number of books by self-described pick-up artists (any number above zero is embarrassing) not to learn about human behavior but to gain tools of revenge. He'll act like a victim even though hes the one ruining relationships.

Age cured this self-affliction, but not soon enough. There arent many things from my teens and 20s I want to do over, but I would go to the Hellmouth and back for a few more youthful years uncursed by Xanderness.

Troy Reimink is a writer and musician who lives in west Michigan.

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Troy Reimink: 'Buffy the Vampire Slayer' helped me become less of a jerk - Traverse City Record Eagle

Pentagon sees more AI involvement in cybersecurity – Defense Systems

Cyber Defense

As the Pentagons Joint Regional Security Stacks moves forward with efforts to reduce the server footprint, integrate regional data networks and facilitate improved interoperability between previously stove-piped data systems, IT developers see cybersecurity efforts moving quickly toward increased artificial intelligence (AI) technology.

I think within the next 18-months, AI will become a key factor in helping human analysts make decisions about what to do, former DOD Chief Information Officer Terry Halvorsen said.

As technology and advanced algorithms progress, new autonomous programs able to perform a wider range of functions by themselves are expected to assist human programmers and security experts defending DOD networks from intrusions and malicious actors.

Given the volume and where I see the threat moving, it will be impossible for humans by themselves to keep pace, Halvorsen added.

Much of the conceptual development surrounding this AI phenomenon hinges upon the recognition that computers are often faster and more efficient at performing various procedural functions; at the same time, many experts maintain that human cognition is important when it comes to solving problems or responding to fast-changing, dynamic situations.

However, in some cases, industry is already integrating automated computer programs designed to be deceptive giving potential intruders the impression that what they are probing is human activity.

For example, executives from the cybersecurity firm Galois are working on a more sophisticated version of a honey pot tactic, which seeks to create an attractive location for attackers, only to glean information about them.

Honey pots are an early version ofcyberdeception. We are expanding on that concept and broadening it greatly, said Adam Wick, research head at Galois.

A key element of these techniques uses computer automation to replicate human behavior to confuse a malicious actor, hoping to monitor or gather information from traffic going across a network.

Its goal is to generate traffic that misleads the attacker, so that the attacker cannot figure out what is real and what is not real, he added.

The method generates very human looking web sessions, Wick explained. An element of this strategy is to generate automated or fake traffic to mask web searches and servers so that attackers do not know what is real.

Fake computers look astonishingly real, he said. We have not to date been successful in always keeping people off of our computers. How can we make the attackers job harder once they get to the site, so they are not able to distinguish useful data from junk.

Using watermarks to identify cyber behavior of malicious actors is another aspect of this more offensive strategy to identify and thwart intruders.

We cant predict every attack. Are we ever going to get where everything is completely invulnerable? No, but with AI, we can change the configuration of a network faster than humans can, Halvorsen added.

The concept behind the AI approach is to isolate a problem, reroute around it, and then destroy the malware.

About the Author

Kris Osborn is editor-in-chief of Defense Systems. He can be reached at kosborn@1105media.com.

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Pentagon sees more AI involvement in cybersecurity - Defense Systems

Humans May Have Played Very Active Role In Desertification Of The Sahara, Research Finds – CleanTechnica

March 17th, 2017 by James Ayre

Humans may have played a very active role in the desertification of the Sahara, according to new research from Dr David Wright of Seoul National University.

The new findings directly contradict the earlier supposition that the rapid shift from a heavily greened landscape to the modern Sahara desert, over just a few thousand years time, was driven entirely by natural processes. (Obviously, if one considers human behavior to be natural, than there is no real distinction, but that doesnt change the fact that people may have played a major role in the desertification of the region.)

In East Asia there are long established theories of how Neolithic populations changed the landscape so profoundly that monsoons stopped penetrating so far inland, commented Wright. Wright then went on to note that evidence of human-driven climatic and ecological change has been documented in Europe, North America, and New Zealand as well, and that similar scenarios could well have occurred in the Sahara.

Nick Fraser, Journal Development Manager, Frontiers in Earth Sciences, provides more: To test his hypothesis, Wright reviewed archaeological evidence documenting the first appearances of pastoralism across the Saharan region, and compared this with records showing the spread of scrub vegetation, an indicator of an ecological shift towards desert-like conditions. The findings confirmed his thoughts; beginning approximately 8,000 years ago in the regions surrounding the Nile River, pastoral communities began to appear and spread westward, in each case at the same time as an increase in scrub vegetation.

Growing agricultural addiction had a severe effect on the regions ecology. As more vegetation was removed by the introduction of livestock, it increased the albedo (the amount of sunlight that reflects off the earths surface) of the land, which in turn influenced atmospheric conditions sufficiently to reduce monsoon rainfall. The weakening monsoons caused further desertification and vegetation loss, promoting a feedback loop which eventually spread over the entirety of the modern Sahara.

If true, that would make for simply yet another version of the age-old human story of unintended consequences. In other words, its yet another show of the fact that humans arent nearly as clever as most of uslike to thinkwe are.

To reiterate that last point, historical study clearly shows that soil erosion and desertification played a significant role in the collapse of many earlier civilizations. And since were talking about North Africa here it should be remembered that after the Roman Republic had more or less depleted the soils of Southern Europe (and entered into the civil war period that led to the birth of the Roman Empire), it colonized the region which still possessed good soil fertility at the time at the expense of the mostly Phoenician locals. (The Afri were one of the Phoenician groups living there at the time, and served as the basis of the name Africa.)

For many of the years that followed, this colonization of North Africa functioned as the breadbasket of the Roman Empire. The current state of North Africas depleted soils is partly the result of the mass-scale agriculture of the time, and partly the result of the overgrazing and abandonment of the aqueducts that followed Islamic conquest. (There was also a brief period when the Germanic Vandals had control of some parts of the region, before the Arabs then pushed them out.)

Commenting on what comes next, Wright stated: There were lakes everywhere in the Sahara at this time, and they will have the records of the changing vegetation. We need to drill down into these former lake beds to get the vegetation records, look at the archaeology, and see what people were doing there. It is very difficult to model the effect of vegetation on climate systems. It is our job as archaeologists and ecologists to go out and get the data, to help to make more sophisticated models.

Overall, Wrights work makes for an interesting interpretation of the available data. Personally, I wouldnt be surprised at all if humans were the primary driver of desertification in the region aided by the climatic turbulence of the times. Theres probably a parallel to be drawn there with modern times

The new findings are detailed in a paper published in the journal Frontiers in Earth Science.

Image bySidy Niang(some rights reserved)

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Tags: desertification, North Africa, overgrazing, Sahara Desert

James Ayre 's background is predominantly in geopolitics and history, but he has an obsessive interest in pretty much everything. After an early life spent in the Imperial Free City of Dortmund, James followed the river Ruhr to Cofbuokheim, where he attended the University of Astnide. And where he also briefly considered entering the coal mining business. He currently writes for a living, on a broad variety of subjects, ranging from science, to politics, to military history, to renewable energy. You can follow his work on Google+.

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Humans May Have Played Very Active Role In Desertification Of The Sahara, Research Finds - CleanTechnica

Climate, not just genetics, shaped your nose, study says – CNN

There's a great variety in nose variation from person to person, yet if you look at different ethnic populations, you will see differences across groups. For example, the distance between the wings of the nose, also known as "nasal alare," are larger in people of West African, South Asian and East Asian ancestry than in people of European ancestry.

So it's easy to understand why many people, past and present, "have this sense that human populations are very distinct and have been separated for a long time," said Mark D. Shriver, lead author of the study and a professor of anthropology at Penn State University. Still, he noted, "human populations have always split and come back together, split and come back together, so there's no separate origin."

In fact, genetic differences between various population groups is not that great. Using noses as just one example, said Shriver, "the surface, the appearance of people in different populations is much greater than what the genetic differences show on average."

To answer this question, Shriver and his colleagues selected 2,637 individuals from a database of about 10,000.

They selected people from four populations: North Europeans, South Asians, East Asians and West Africans. Shriver and his team looked at 3-D photos of each individual and examined the width of the nostrils, the distance between nostrils, the height of the nose, nose ridge length, nose protrusion, external area of the nose and area of the nostrils.

"So we have multiple cameras that image a person's face, either simultaneously or in a carefully constructed series, and from those multiple angles, you can derive the shape of a face as a point cloud," Shriver said. The resulting 3-D image allows you to "take careful measurements usually calibrated down to a tenth of a millimeter," he said.

Through complex analysis of the data, the researchers learned that the width of the nostrils and the base of the nose measurements differed across populations more than could be accounted for by genetic drift.

Genetic drift refers to the fact that some people leave behind more descendants (and therefore more genes) than others just by chance and not necessarily because they are healthier or better survivors.

If not genetic drift, then natural selection must have played a hand in the evolution of nose shape in humans. Natural selection refers to the fact that people better adapted to their environment are the ones who survive and reproduce, leaving behind their genes.

"Natural selection is usually divided into ecological selection, simple survival and sexual selection aspects of mate choice and competition," Shriver said.

Exploring how local climate might have contributed to differences in nose shape, the researchers looked at the distribution of nasal traits in relation to local temperatures and humidity and found that the width of the nostrils strongly correlated with temperature and absolute humidity.

Your nose and nasal cavity function as your personal air conditioner, warming and moistening air before it reaches your lower respiratory tract. In the late 1800s, British anatomist and anthropologist Arthur Thomson observed that long and thin noses occurred in dry, cold areas, while short and wide noses occurred in hot, humid areas.

Since narrower nostrils allow the nose to humidify and warm the air more efficiently, this was probably essential in cold, dry climates; people with narrower nostrils probably fared better and had more offspring than people with wider nostrils in locations farther from the equator.

"Some of the nose variation is really the climate; some of it's not," Shriver said, noting that sexual selection played a role, as well, with people choosing mates based on notions of beauty, such as finding a smaller nose more attractive.

"The fact that we find such big male-female differences in all of the nose traits is also consistent with sexual selection having a hand," he said. Still ecological selection and sexual selection often reinforce each other, and the study provides evidence that both types of selection have helped shape the nose.

The finding might have some practical application, providing important clues in criminal investigations, Shriver said.

"We didn't get into it in this paper, but (the research) is highlighting some of the variety of data we have," he said. He and his colleagues have been creating 3-D photos and collecting measurements and other data on thousands of people for over 12 years.

"The practical application is something we call 'forensic molecular photo fitting': making a phenotypic prediction of a person from evidentiary DNA," Shriver said.

In other words, if a crime victim's identity isn't known, Shriver can deduce what the person might look like based on DNA from their skeletal remains. The appearance of a perpetrator might be based on DNA from some material left behind at the crime scene.

"More than half of my research effort, the end product, will be molecular photo fitting," said Shriver, who offered one example of why there is interest in this application.

"If you can make a phenotypic prediction, maybe that face or even that genetic ancestry can be quite helpful in directing the investigation," Shriver said. "A lot of good detectives and police officers really understand the range of variation within different populations."

Despite grants from the US Department of Defense and other funding sources, some scientists remain skeptical.

"Although interesting, I think that the study oversimplifies the possible adaptation that has occurred by simply evaluating the external shape," said Dr. Stella Lee, an assistant professor at University of Pittsburgh School of Medicine, who was not involved in the research. "The main limitation of this study is that only the external shape of the nose was analyzed rather than actual nasal airflow, humidity and internal nasal measurements."

"The inside of the nose is lined by a multitude of cilia (which look like a shag carpet under the microscope) that are constantly providing clearance of mucus, pathogens and inhaled particulates to the back of the nose by beating in a rhythmic motion," Lee said. "It is amazing that our noses can differentiate between potentially harmful pathogens and innocuous agents."

Still, Lee noted that the authors themselves acknowledged the possibility of oversimplification.

Seth M. Weinberg, an associate professor at the University of Pittsburgh, said anthropologists have long been interested in the nose as one example of human adaptation.

"This study advances our understanding of the complex picture of human facial diversity," said Weinberg, who had no role in this project, though he has collaborated with several of the authors.

The research attempts to connect the "shape of the external human nose to geographically relevant ecological factors" operating throughout our evolutionary past up to the modern day, he said.

"Researchers have only recently begun to uncover the genetic basis of traits like nasal shape in humans," Weinberg said. "Studies like this can help us to frame those genetic findings within a broader context."

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Climate, not just genetics, shaped your nose, study says - CNN

Tame the hype: Is medical genetics plagued by unfilled promises? – Genetic Literacy Project

Recently, I read an article promising that medical genetics willmake medicine predictive and personalized through detailed knowledge of the patients genome.

The thing is, the article is from 1940Looking back, we knew almost exactly nothing about the genetic mechanisms of human disease.

While inflated medical promises are hardly peculiar to molecular medicine, that field does seem particularly prone to breathless rhetoric.

Bluster, overstatement and aspirations masquerading as hard targets have no single cause. One reason, surely, is the heady sense of impending omnipotence that accompanies major technological and scientific advances. Charles Darwins theory of evolution by natural selection, the cracking of the genetic code, [and] CRISPR all were followed by grandiose claims of the imminent total control over lifes fundamental processes.

Every generation of scientists looks back and shakes its collective head in condescending disbelief at how little the previous generation knew, rarely stopping to reflect that the next generation will do the same.

Its time to push back. One way is to hold scientists, philanthropists and the press accountable[We should fund]science liberally, but reward knowledge more than market value.Encourage science literacy, not just cheer-leading. And teach skepticism of technology, medicine and the media.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post:Genetic research: A money laundering business or a gateway to miracles?

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Tame the hype: Is medical genetics plagued by unfilled promises? - Genetic Literacy Project

First ‘three-parent babies’ could be born in UK this year as docs secure licence to perform controversial IVF – The Sun

THE first three-parent babies could be born in the UK this year after doctors were given the go-ahead to start performing controversial new IVF therapy.

The Human Fertilisation and Embryology Authority (HFEA) has granted a licence to a team at the University of Newcastle, who have pioneered the new treatment.

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HFEA chair Sally Cheshire announced the development in her opening speech at the authoritys annual conference this morning.

She said: This significant decision represents the culmination of many years of hard work by researchers, clinical experts, and regulators, who collectively paved the way for Parliament to change the law in 2015, to permit the use of such techniques.

Patients will now be able to apply individually to the HFEA to undergo mitochondrial donation treatment at Newcastle, which will be life-changing for them, as they seek to avoid passing on serious genetic diseases to future generations.

The treatment has the potential to allow couples who carry, and therefore risk passing on, deadly genetic diseases to conceive healthy babies.

Though it is dubbed a three-parent treatment,babies born as a result of the therapy would only inherit personality traits, those that affect appearance and other features that make a person unique, from theirmum and dad not the donor.

The move comes after the HFEA gave the therapy, called mitochondrial donation, the green light in December last year.

Speaking after that historical decision, MrsCheshire said: This is life-changing for those families.

But critics have warned it marks the first step towards so-called designer babies.

The NHS is now poised to spend 8million offering the IVF to 25 couples.

The licence is the first stage of the process, and gives the Newcastle clinic the green light to perform the procedure.

The second stage requires each patient application to be individually approved by the HFEA, they confirmed.

Earlier this year the first baby to be born using the technique was welcomed into the world by his parents in Mexico.

The baby boy was born in April after his parents, who are from Jordan, were treated by a team of American specialists in the country.

Scientists at the University of Newcastle, which has been at the forefront of pioneering the treatment, have already lined up women to have the therapy, known as mitochondrial replacement therapy.

The team hopes to treat up to 25women a year with NHS funding.

Prof Sir Doug Turnbull, who has led the team at Newcastle in developing the new IVF therapy, said he is delighted for patients.

This will allow women with mitochondria DNA mutations the opportunity for more reproductive choice, he said.

Mitochondria diseases can be devastating for families affected and this is a momentous day for patients who have tirelessly campaigned for this decision.

He said in December, his team will aim to treat up to 25 carefully selected patients each year, and would offer follow-up care for any children born.

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Fertility experts across the UK also welcomed the development.

Professor Adam Balen, chair of the British Fertility Society, said the granting of a licence to the Newcastle centre marks a historical step towards eradicating genetic diseases.

The decision is the latest step in a 10-year process from the first proof of concept studies.

Dr Jeremy Farrar, director of the Wellcome Trust, who funds the centre for mitochondrial research at Newcastle said: Affected couples in the UK who have dreamt of having a baby free of mitochondrial disease will have an option open to them for the first time, he said.

Now we must give the first patients and their doctors the time and space to discuss the next steps with the patience, sensitivity and scientific rigour that they have displayed throughout.

Fertility clinics in the UK will not automatically be given the right to offer the treatment.

Rather, each clinic will have to apply to the HFEA for permission to do so.

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Prof Balen said given their pivotal role in developing the treatment the Centre for Life at Newcastle University is likely to be the only centre approved to offer the therapy.

The pioneering therapy aims to prevent potentially fatal diseases being passed from parents to their offspring.

Babies receivingmitochondrial replacement therapy would receive a tiny amount of DNA from a third person besides their mother and father.

Fertility specialists carrying out the treatment will aim to replace abnormal genes in themitochondria small structures that are found in every human cell.

Mitochondria are small structures found in our cells. They generate energy that is used to power every part of our body. Mitochondria have their own DNA, which only controls mitochondrial function and energy production, according to the Wellcome Trust. This is completely separate from our nuclear DNA, which is what makes us who we are, governing our appearance and personality. Mitochondrial disease can be fatal, affecting multiple organs. It includes diabetes, heart problems, epilepsy and stroke-like incidents, and in serious cases death. Mitochondrial DNA disease is passed from mother to baby. The new mitochondrial donation technique, uses DNA from the mitochondria of a healthy donor, the nucleus of a mothers egg and a fathers sperm to create an embryo. The technique allows for those women who carry potentially fatal genetic mutations to have healthy babies. As the nuclear DNA is not altered, mitochondrial donation will not affect a childs appearance or personality or any other features that make a person unique. It simply allows for a child to be free of mitochondrial disease.

Source: The Wellcome Trust

To do so involves taking the DNA from themothers egg that bears thefaulty genes, and transferring it into a donor egg, with healthy mitochondria.

Because the nucleus from the mothers egg is used the technique does not affect the babys appearance, personality, or other traits that make a person unique.

It simply allows the mitochondria which only controls a cells energy production to function normally, allowing a child to be born free of mitochondrial disease, which can prove fatal.

Mitochondria only hold around 0.1per cent of a persons DNA, which is always inherited from the mother and has no influence over individual characteristics.

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But faulty mitochondrial DNA can lead to a wide range of potentially fatal conditions affecting vital organs, muscles, vision, growth and mental ability.

In theory, mitochondrial replacement can not only prevent a child developing inherited diseases, but also protect future generations.

Last year, the UK became the first country in the world to legalise mitochondrial replacement after MPs and peers voted in favour of allowing it.

Critics say the technique is not fool-proof and small numbers of faulty mitochondria may still be carried over into the child.

They also argue that unforeseen problems might occur once the procedure is used to create human babies.

For instance, replacing the DNA might have more of an impact on personal traits than has been envisaged.

Dr David King, from the watchdog group Human Genetics Alert, said the HFEA had approved experiments on babies using the technology that was dangerous and medically unnecessary.

He accused experts backing the treatments of shameless emotional blackmail and scientific misrepresentations.

Dr King added: This decision opens the door to the world of GM (genetically modified) designer babies.

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First 'three-parent babies' could be born in UK this year as docs secure licence to perform controversial IVF - The Sun