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Extremism in Defense of Autonomy – Townhall

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Posted: Feb 23, 2017 12:01 AM

When confronted with opposition to abortion, many feminists reflexively assert that it is (Their) body and, therefore, (their) choice. Notice that I have used the term assert instead of argue. In order for an assertion to become an argument it must be accompanied by evidence. There simply is no evidence to support the position that the unborn is merely an extension of the womans body.

There are two ways to respond to this unsupported assertion. One is to simply quote from embryology textbooks, which uniformly conclude that the unborn is a distinct, living, and whole human being from the point of conception. Another is to share images of what the unborn child looks like at the earliest stages when surgical abortion is performed, which is around seven weeks after conception. By choosing this latter option, one can simply count the clearly discernible fingers on the blob of tissue and see that more than one body is involved. Pregnant women dont have four hands and twenty fingers.

Using scientific evidence to point out that it is not merely her body and her choice will usually force the pro-abortion choice advocate to modify her position with something like the following: Ok, there is another body involved but its still my choice. In other words, I dont care about the other body. My bodily rights still prevail!

Philosophically speaking, this is a hard position to defend. In effect, using a bodily autonomy argument to defend abortion is tantamount to saying that one can advance bodily autonomy through the act of dismembering bodies. At some point, this kind of thinking produces more than mere cognitive dissonance. It leads to a crisis in our conception (sorry) of human equality.

It should go without saying that you can use this justification for abortion only if a womans right to bodily autonomy is absolute. The absurdity of such absolutist claims should be obvious. If they are not, please consider a thought experiment originally offered by pro-abortion choice blogger Paul W. (paraphrased and modified slightly by yours truly).

First off, imagine that a woman enjoys being pregnant. And dont laugh. I have a good friend who has had eight children with his wife. Whenever I see her and she is pregnant she is beaming. When she is not pregnant she will tell you that she wished she were pregnant. In fact, she is never happier than when she is pregnant.

Now, just imagine that a new form of technology comes into existence, which allows a woman to remain pregnant as long as she wants. In other words, it stops the baby within her from developing past a certain point. All she has to do is to take a pill or get some sort of injection and the baby will stop growing and remain within her womb forever.

Further, also imagine that a woman gets pregnant at the age of 20, takes advantage of the new technology, remains pregnant, and lives until the age of 90. For 70 years, there is a tiny dwarf living inside of her who is fully aware of whom he is and who wants to escape to live a normal life. But, alas, he cannot. She has boldly proclaimed, It is my body and my choice! Nobody passes through my vagina without my permission! So her dwarf baby remains inside her womb trapped in involuntary servitude in rigid adherence to the principle of bodily autonomy.

The thought experiment proffered by Paul W. may well produce the objection that it doesnt apply to abortion, as the fetus is neither aware of its surroundings nor desirous of escape. But the solution to that is pretty simple. Just as one injection could stop the baby from growing, a second injection could knock it out as soon as it starts developing self-awareness. There would be no violation of human rights as long as the little human didnt know what was happening. In a sense, the bodily autonomy zealot could just borrow a page from the playbook of the rapist who sedates his victims in advance.

The bodily autonomy justification for abortion is indeed barbaric. But, unfortunately, it is often made to sound defensible by a much more famous thought experiment. That well-known hypothetical will be the subject of a future column.

To be continued.

Breaking:Alan Colmes Passes Away At Age 66

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Extremism in Defense of Autonomy - Townhall

Sandra Oh Returning To ‘Grey’s Anatomy’? She Reveals Whether She’d Ever Come Back – Hollywood Life

Greys Anatomy fans have been dying to find out if Sandra Oh will return to the series ever since her character, Dr. Cristina Yang, left Grey Sloan Memorial Hospital back in 2014. Now Sandra herself is speaking out!

At this point No, I dont think so,Sandra Oh, 45, said when she was asked about returning to Greys Anatomy during her recent appearance onAccess Hollywood Live. Though the actress was there to promote her new movieCatfight, along with her co-star Anne Heche, of course co-hosts Kit Hoover and Natalie Moralesjust had to ask if shed reprise her role as Dr. Cristina Yang! Hello, she was Meredith Greys (Ellen Pompeo) best friend for 10 wonderful seasons!

Sandra, aGolden Globe winner for her performance on the ABC drama,was also asked if she would come back justfor the series finale (when it happens), to which she said she has talked with showrunner Shonda Rhimesabout the idea. I just dont know. It would have to feel right, she said.

As an actor, as an artist, its a full life that one has, Sandra said of her career. And as I look back to that time, which is extremely important and deeply meaningful to me, and it means a lot to me that a whole generation, a new generation of fans are discovering the show. So it means a lot.

The Catfightactressdecided to leave the powerhouse series back in 2014, so Cristina was written out as going to work overseas. Ever since then we have definitely missed Merediths person and we know she has too! So we will keep holding out hope that one day Sandra might come back, if only for an episode!

HollywoodLifers, do you think that Sandra will ever come back toGreys Anatomy? Give us all your thoughts below!

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Sandra Oh Returning To 'Grey's Anatomy'? She Reveals Whether She'd Ever Come Back - Hollywood Life

EssayThe Neuroscience of Self-directed Learning – Chief Learning Officer

Breaking down what makes top performers so great, and setting up practice and reflection to stimulate certain neural responses, can help you clone your best talent.

February 21, 2017

by William Seidman

The best talent is almost always deeply engaged and incredibly productive. Wouldnt it be great if learning leaders could clone those people? Well, they can.

There are two parts to being able to clone your people: the ability to reverse engineer the top performers to really understand what makes them extraordinary, and the ability to quickly and efficiently develop others to think and act like those top performers.

Self-discovery allows an organization to quickly and effectively reverse engineer top performers. Self-directed learning, based on advances in neuroscience, enables an organization to quickly develop everyone to be like the best.

We began with a question that can be quite difficult to answer: How do top performers actually become top performers? As with trying to reverse engineer top performers, there was neither good information nor robust methodologies on how to develop lesser performers into top performers.

The closest answer is that experts spend 10,000 hours working to become an expert, with no definition of what that work meant. Ten thousand hours of unfocused learning was hardly going to meet our requirements. Fortunately, starting about 2005, the emerging neuroscience of learning suggested a way to solve this problem.

Neuroscience showed the basic building block of all learning is the rewiring of neurons into new patterns. What causes neurons to rewire? The scientific saying is neurons that fire together wire together. Firing together means a sufficient number and depth of meaningful experiences around a defined set of attitudes and behaviors cause the brain to rewire or learn the new patterns. Once rewired, these patterns are the new unconscious competence.

But what experiences cause the brain to rewire and, most critically, how do you get non-top performers to want to become top performers enough to do the practice required to rewire their neurons? Lets answer the second question first. Here again the breakthrough came from neuroscience. The science shows that certain types of images and actions cause neural changes that drive our attitudes and behaviors. When someone feels they are making a contribution to a greater social good for family, teammates, the organization and/or society, their brain releases endorphins and dopamine called a dopamine squirt which make them feel great and more receptive to new ideas.

Similarly, if a person writes down their greater purpose, the act of writing suppresses portions of the brain associated with fear and resistance to change and stimulates portions of the brain associated with a sense of greater control, also making them more open to new ideas. Finally, if all of this is done with others in some sort of social group, other neurochemicals serotonin and oxytocin are released that cause people to want to promote collaboration and group success.

It is possible to create an effective methodology to rapidly develop non-top performers to become top performers. It would need to include:

Most of these ideas should sound familiar from the protocol for reverse engineering top performers. Top performers are driven by a compelling purpose to achieve a greater social good and work hard to achieve mastery by continuously practicing their skills. The key is to present images from the reverse engineering of the top performers to non-top performers in ways that stimulate the desired neural responses.

The process begins with the top performers description of their purpose. By presenting the top performers purpose to groups of non-top performers and asking them to identify, discuss and write ways they too can contribute to the great purpose, all of the above neural changes occur. The non-top performers want to become top performers because they too can be part of a greater purpose and it feels great. Further, because our brains are very efficient at processing images associated with a greater purpose, an initial powerful motivation can be stimulated in a few minutes and firmly entrenched in about an hour.

Moving to the need to practice, by asking the top performers how they learned to become top performers, learning leaders can identify their most valuable learning experiences. By modifying these high yield experiences so non-top performers can try them in their own environment, repeating this practical application multiple times in rapid succession and then sharing the learning with a social group, the time needed to become a top performer can be reduced to 40 hours or less.

These methodologies are so simple, fast and robust they can be provided using a protocol similar to that used for reverse engineering top performance. We call this protocol, neuroscience-based self-directed learning, and its prompts guide a non-top performer to:

As a result, anyone, anytime, residing anywhere in the world can quickly learn to think and act like the top performers. Essentially, you can clone your best people.

William Seidman is the CEO of Cerebyte Inc., a company focused on creating high-performing organizational cultures, and co-author of The Star Factor. Comment below or email editor@CLOmedia.com.

Tags: neuroscience, self-directed learning, top performers

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EssayThe Neuroscience of Self-directed Learning - Chief Learning Officer

The Neuroscience of Fearful Memories and Avoidance Behaviors … – Psychology Today (blog)

The Ji Lab at Baylor College of Medicine investigates how the neural circuits in the brain encode, consolidate, and retrieve memories using lab rats.

Source: Ji Lab/Baylor College of Medicine

Specific neurons in the hippocampus (called hippocampal place cells) remember when and where your brain experiences a broad range of sensory stimulation and emotions, including fear. Hippocampal place cells also drive subsequent fear-based avoidance behaviors, according to a new rodent study from the Ji Laboratory at Baylor College of Medicine.

The February 2017 study, Hippocampal Awake Replay in Fear Memory Retrieval, was published online ahead of print today inNature Neuroscience. This is the first time neuroscientists have identified specific patterns of electrical activity in the hippocampal place cells of lab rats associated with specific memories. In this case, the memory of afearful experience.

Hippocampal place cellsare activated anytime a human or animal moves within and between locations. These place cells keep track of everywhere your body goes and tag each location with a specific neural code that includes sensory perceptions based on stimuli that evokepleasure,pain, reward, etc.

All animals (including humans) seek pleasure and avoid pain. Therefore, it makes sense that when hippocampal place cells tag a specific location as being associated withphysicalor psychologicalpain, parts of the brain becomehardwired to avoid this location. From an evolutionary standpoint, learning to avoid life-threatening environments is key to any species' survival.

At the beginning of this new experiment, the researchers inserted tiny probes to monitor the electrical activity generated by neurons in the hippocampus. Then, they conditioned a fearful memory by exposing lab rats to mild foot shocks in a specific shock zone as the rats explored a troughlike track. Lastly, the researchers observed neural activity in hippocampal place cells as each lab rat was placed back on the track and began to explore.

The researchers found that specific place cells linked to the 'shock zone' were reactivated anytime a rat got close to the place where foot shocks had been administered. The anticipatory thought of getting a shock appeared to triggeravoidance behaviors that caused the rodents to bypass the shock zoneand avoid crossing the fearful path.

According to the abstract of this study, the fear reactivation of place cells occurred in ripple-associated awake replay of the exact location linked to a cell sequence that had been encoded along the path inthe shock zone.

These findingsreveal a specific hippocampal place-cell pattern underlying inhibitory avoidance behavior. Thisstudy also provides strong evidence for the involvement of awake replay in fear memory retrieval.

In recent years, a few different neuroscientific studies have reported that hippocampal place cells play a central role in storing location data and forming episodic memories. However, exactly how 'place cells' retrieve memories associated with a particular placeand subsequently drive avoidance behaviorshas remained a mystery until now.

In a statement, Daoyun Ji, associate professor of molecular and cellular biology at Baylor College of Medicine,described the recent findingsfrom his lab:

"Our laboratory rats cannot tell us what memory they are recalling at any particular time. To overcome that, we designed an experiment that would allow us to know what was going on in the animal's brain right before a certain event.

Interestingly, from the brain activity we can tell that the animal was 'mentally traveling' from its current location to the shock place. These patterns corresponding to the shock place re-emerged right at the moment when a specific memory is remembered.

We are also interested in determining how the spiking patterns of place neurons in the hippocampus can be used by other parts of the brain, such as those involved in making decisions."

This study from Daoyun Ji's Lab breaks new ground by discovering that milliseconds before a lab rat decides to avoid going back to a place where it previously had a fearful experience, the brain is recalling specific memories associated with the exact physical location where the fearful experience occurred.

Like most people, I have an innate fear of rats. Staring at the enlarged image of the rat below evokes a slight fear-based responseand is probably encoding my hippocampal place cells to the place I'm sitting now as I stare at this image while typing this blog post. Your hippocampal place cells are probably being activated, too. If this image makes you uneasy or sticks in your mind, itwill most likely be linked to when and where you are reading this by yourhippocampal place cells.

Source: Ji Lab/Baylor College of Medicine

Zooming in on this potentially menacing image of a rat from Ji'sLab barreling down a track towards the viewer triggers flashbacks in my mind's eye to the torture chamber "Room 101" from George Orwell's1984.

While being brainwashed by the Thought Police inRoom 101, WinstonSmith (the protagonist in1984),must confront his biggest fear: A wire cage that fits snuggly on a person's head with a trap door that houses two very large (and ravenous) rats eager todevour the cage wearer's face.

Hypothetically, if Winston Smith's hippocampal place cells could be measured in Ji's neuroscience laboratory, Room 101would evoke fearful memories and avoidance behaviors much like the lab rats who steered clear of the 'shock zone' in their habitrail.

The next goal of Ji and his colleagues is to investigate whether the hippocampal spiking patterns they identified are absolutely required to guide (or misguide) humanand animal behavior.

The researchersalso plan to explore what role spiking patterns in the hippocampus might play in diseases that involve memory loss, such as Alzheimer's disease. Stay tuned for more cutting-edge research on hippocampal place cells in the months and years ahead.

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The Neuroscience of Fearful Memories and Avoidance Behaviors ... - Psychology Today (blog)

This Neuroscience Study Says Ads Are More Effective on Publishers’ Websites Than Social News Feeds – FishbowlDC (blog)

Publishers own websites couldbe mightier than the almighty news feed when it comes to impact for advertisers, according to newneuroscience research comparing social platforms and premium sites.

Neuro-Insight, a neuro-marketing company, examinedcontent from four major publishersCond Nast, Forbes, Time Inc., and The Atlanticand found that test subjects were 16 percentmore likely to find web postsrelevant or engaging than similar content in social feeds.Tounderstand how readersrelated to different types of content, Neuro-Insight connected 100 people with neuro-mapping technology and showed themvideos inaFacebook newsfeed or a publishers website.

Along with being more personally relevant, publishers websites might be more memorablethey had a 19 percent greater impact on the rational left side of the brain, and an 8 percent greater impact on the emotional right side of the brain, the study found. Memories of video ads were also more detailed on the websites, with 8 in 10performing better than in a social feed.

The results shouldbe welcome news for publishers, which continue to struggleto monetize contenton mobile and social platforms. Some estimates saymajor tech players like Google and Facebook get as much as 85 cents for every new digital dollar spent on advertising.

What weve always understood is that there is strong engagement, said Caryn Klein, Time Inc.s vp of research and insights. But how is that halo to an advertisers message? Thats always been a question. We know there is high engagement, but what were seeing here is that when you go into what the brain is doing, were proving here that there is a lot more resonance of the message from a memory standpoint.

Teads chief marketing officer Rebecca Mahony said the goal was to give publishers a better view of how effective their ads really are.

Time Inc. is increasingly betting on the future of video. The company saw a 150 percent growth in video starts from 2015 to 2016for a total of 4.6 billionaccording to its fourth-quarterearnings.

The study, commissioned by Teads, anonline video advertising firm, featured 15-second ads abouteverythingfrom tech and CPG to fashionand food. Teads chief marketing officer Rebecca Mahony said the goal was to givepublishers a better view of how effective their ads really are. She said in-depth, long-form storiesalso make a reader more invested, which in turn helpsthem recalladsbetter than when theyre passively scrolling.

Certain brands also perform better than others across platforms. For example, health food, coffee and hospitality brands advertising on publishers sites had a big impact onthe detail-oriented left-side of the brain. However, ecommerce and consumer electronics brands resonated withthe right side of the brain. An interesting caveat:hospitality brands and ads for TV programsfaredbest on Facebook.

Advertising can drive a skew, said Matt Engstrom, Teads director of content and insights. It either impacts the detailed left side of the brain more stronglyor the right side of the brain more strongly. And when that sort of imbalance aligns with the reaction of the content on the brain, that makes the advertising more likely to be impactful.

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This Neuroscience Study Says Ads Are More Effective on Publishers' Websites Than Social News Feeds - FishbowlDC (blog)

Frontier Pharma: Versatile Innovation in Immunology Report 2017 – Large Therapy Area Pipeline with a High Degree of … – Yahoo Finance

DUBLIN--(BUSINESS WIRE)--

Research and Markets has announced the addition of the "Frontier Pharma: Versatile Innovation in Immunology - Large Therapy Area Pipeline with a High Degree of Repositioning Potential" drug pipelines to their offering.

Immunology is a large therapy area characterized by disorders of the immune system - specifically an aberrant immune response against healthy tissues present in the body, leading to chronic or acute inflammation. Depending on the specific site affected, this can lead to various types of chronic pain and loss of mobility, and have a negative impact on quality of life.

This disease area has a total of 2,145 products in active development, trailing only oncology, infectious diseases and central nervous system disorders in terms of pipeline size. There are a total of 529 immunology pipeline products that act on first-in-class molecular targets, representing approximately 40% of the total immunology pipeline for which the molecular target was disclosed.

Due to a degree of crossover between immunology indications in terms of their underlying pathophysiology, it is not uncommon for products being developed for this therapy area to have developmental programs testing them across multiple indications.

Approximately one-fifth of first-in-class pipeline products are in development for two or more indications within the therapy area. This presents an opportunity for companies to develop innovative products across multiple immune disorders, and therefore reach a larger pool of patients than products developed for single indications.

Scope

- What are the key points of overlap in the pathophysiology of immune disorders?

- What is the current standard of treatment across these markets, and what lessons can be learned by companies seeking to innovate and build on these products?

- Which molecule types and molecular targets are most prominent within the pipeline?

- Which first-in-class targets are most promising?

- Do immunology products attract high deal values, and which specific product types are able to attract the highest values?

- Which molecule types and molecular targets dominate the deals landscape?

Key Topics Covered:

1 Table of Contents

2 Executive Summary

3 The Case for Innovation in the Immunology Market

4 Introduction

5 Pipeline Landscape Assessment

6 Immunology Signaling Network, Disease Causation and Innovation Alignment

7 First-in-Class Target and Pipeline Program Evaluation

8 Strategic Consolidations

9 Appendix

For more information about this drug pipelines report visit http://www.researchandmarkets.com/research/z8fppq/frontier_pharma

View source version on businesswire.com: http://www.businesswire.com/news/home/20170221005737/en/

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Frontier Pharma: Versatile Innovation in Immunology Report 2017 - Large Therapy Area Pipeline with a High Degree of ... - Yahoo Finance

Immunology Space Attracting High Levels of Investment – Drug Discovery & Development

With a total of 2,145 products currently in development, the immunology market is experiencing a high level of investment compared to many other therapy areas, and companies working within it are seeking to build on the clinical and commercial success of marketed products such as tumor necrosis factor-alpha (TNF-) inhibitors, according to business intelligence provider GBI Research.

The companyslatest reportstates that, within immunology, the largest pipeline segments are general treatment of inflammation, with 510 products currently in development, and rheumatoid arthritis, with 488. Additionally, psoriasis, inflammatory bowel disease, transplantation, ulcerative colitis, lupus, and allergies are all substantial indications with over 100 pipeline products in development.

The immunology pipeline is highly diverse in terms of molecule type. Unlike the market, which is mostly limited to small molecules, the pipeline contains a wide range of other molecule types including monoclonal antibodies (mAbs), gene therapies, vaccines, and cell therapies.

Due to a degree of crossover between immunology indications in terms of their underlying pathophysiology, it is not uncommon for pipeline products to undergo developmental programs testing them across multiple indications. The majority of first-in-class pipeline products are being developed for a single indication, but approximately a fifth are in development for two or more indications within the therapy area.

While small molecules account for 91% of marketed products, they comprise only 43% of the pipeline. Both mAbs and proteins account for a much higher proportion of the pipeline than the market, and a number of other molecules that do not yet have a presence in the market, such as gene therapies, vaccines, and cell-based therapies, have a well-established presence in the pipeline, that is not limited to the early stages of development.

In terms of the market landscape, a total of 497 licensing deals and 433 co-development deals in the immunology therapy area were identified as having been completed between 2006 and 2016, with a combined aggregate value of $46 billion.

This high level of deal-making activity is indicative of a strong willingness on the part of pharmaceutical companies to engage in strategic consolidations in order to mitigate some of the risks associated with drug development in the immunology therapy area. Considering the very strong commercial performance of products in the immunology market, companies have a meaningful incentive to invest in such products.

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Immunology Space Attracting High Levels of Investment - Drug Discovery & Development

Human Behavior and Evolution Society

HBES is a society for all those studying the evolution of human behavior. Scientific perspectives range from evolutionary psychology to evolutionary anthropology and cultural evolution; and the membership includes researchers from a range of disciplines in the social and biological sciences. Our membership is worldwide.

The two main activities of HBES are holding an annual conference and running a journal called Evolution and Human Behavior (EHB). The conference provides a forum to present and learn about current research in the field, and includes invited plenary talks from leading scientists in the field. The 2017 meeting will take place May 31st to June 3rd in Boise, Idaho and features talks from anthropologists Valerie Curtis, Rebecca Bliege Bird, Peter Gray, and Rebecca Sear; zoologistRufus Johnstone; psychologists Martie Haselton and Cristine Legare; and primatologist Michael Tomasello.

Members of HBES receive a free subscription to EHB, a discount on the journal Human Nature, reduced registration at the annual HBES conference, and a biannual newsletter. Members are also eligible to apply for funds to host meetings on topics relevant to the goals and mission of HBES. Learn more about becoming a member of HBES.

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Human Behavior and Evolution Society

Owner of new private equity fund says impact investing is ‘the way of the future’ – Greenwich Time

Photo: Matthew Brown / Hearst Connecticut Media

Owner of new private equity fund says impact investing is the way of the future

A longtime Greenwich resident has started a private equity fund committed solely to investing in renewable energy projects.

Impact investing is the way of the future in finance, according to Thomas Yee, who recently started GCT Anchor Fund. The venture, which has its offices in Stamford, began building up capital last fall, but Yee already has big expectations for its success.

Yees team plans to invest in new renewable energy projects overseas, foster their growth and ultimately sell them off. We take the raw project and grow it, Yee said. It requires technical expertise in these particular areas.

Yee expects the results will net a big profit, he said.

The market for investing in renewable energy projects in America is saturated, he said, so the fund will focus on working with ones abroad, such as in Portugal and Argentina.

Overseas theres more risk but opportunity for higher returns, Yee said, whose background includes working as a trader at Moore Capital Management and in the renewable energy sector.

His expertise in renewable energy, particularly in solar energy, together with a carefully-curated team equips GCT Anchor Fund with the tools to turn a profit for its investors while making a positive impact on the environment with its projects, Yee said.

We view social and environmental sustainability as a strategic imperative and as a select investment opportunity with a disciplined focus for acquiring investments from a pipeline of clean tech projects that offer high and steady returns with minimal market risk, the fund says on its website.

Opportunities are limited for investors to make money since the birth of large regulatory measures, such as the Dodd-Frank Wall Street Reform Act, combined with highly volatile markets, Yee outlines in an industry paper titled How to Obtain Alpha in Todays Volatile and Unpredictable Markets.

His new funds emphasis on impact investing derives from Yees belief in its ability to make clients money, but it also has a lot of positive socio-economic ramifications, Yee said. It provides a social ethic, creates jobs and the economy increases. Theres a need for society to develop the most efficient energy.

In addition to his new fund, Yee is working on another project he hopes will do even more to revolutionize the world of finance. As outlined in his paper, market volatility plays a big role in frustrating investors portfolios.

Right now, theres no existing model that can quantify a sudden change in the market, Yee said. Computers dont provide for the financial effect of human emotions.

Its no small undertaking, but Yee hopes to one day produce a model that can react to any market swing, including the black swans. It would take into account the human effect on market volatility and anticipate a trade beneficial to investors. The answer to creating such a model comes from Yees academic studies in ontology, which he describes as a comprehensive set of meanings which describe human behavior.

Creating an algorithm which can translate expected human behavior into trades with a high rate of return is my real interest, Yee said.

MBennett@greenwichtime.com, 203-625-4411; Twitter @Macaela_

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Owner of new private equity fund says impact investing is 'the way of the future' - Greenwich Time