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Structural biology: X-ray crystallography of medically important proteins.

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

Structural Biology: Viral-Host Interactions and Enzyme Dynamics

Prediction of RNA structure and functions and computational design of RNA-based therapeutic strategies.

RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.

Combinatorial biology applied to cancer detection and therapy.

Enzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.

Nucleotide receptors in inflammation and wound healing.

Studies of gene expression and replication, epigenetics, natural product biochemistry; improvement of science education in K-12 schools.

Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens.

Control of gene expression by plant growth regulators.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Transmembrane receptors and sensory transduction in bacterial chemotaxis.

Protein trafficking in innate immunity, immune signaling and heavy metal toxicity, plant-pathogen interaction.

NMR investigations of RNA structures and virus:host interactions in HIV-1 replication.

Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.

Single molecule biophysics.

Study of small signaling molecule-mediated defense responses against biotic stress and lipid metabolism in plant.

Metabolomics, Biological mass spectrometry, Bioanalytical chemistry, LC-UV-MS-SPE-NMR

Biochemical genetics and epigenetics of estrogens and related receptors.

Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.

Cell-cell interactions in pollen recognition and rejection.

Protein targeting and folding in plants, organelle biogenesis, posttranslational modifications.

Proteomics using advanced mass spectrometry and 2D gel electrophoresis.

Carbohydrates and cancer.

Biochemical and physiological function of trace elements. Metabolism and bioavailability of trace elements.

Proteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions; proteomics of drought stress responses.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Regulation of metal nutrition and impacts on common human diseases.

Collagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.

Nitrogen and nitric oxide metabolism in plants.

Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging; phage display.

Metabolism, signal transduction, protein kinases and phosphorylated proteins in plants.

Professor Emerita of Biochemistry and Wurdack Chair Emerita of Biological ChemistryMember, National Academy of Sciences573-884-4160

Molecular chaperones in protein export; analysis of protein-protein interactions.

Reproductive biology: signaling between conceptus and uterus; stem cells.

Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.

Structure-function of crystallins, role of ocular proteases and molecular basis for cataract development.

Students' use of scientific evidence, instructional decision making, classroom assessment, English language learners, design of instructional materials.

MSMC Endowed Professor of Soybean BiotechnologyCurators' Distinguished Professor of Plant SciencesJoint Curators' Distinguished Professor of Biochemistrystaceyg@missouri.edu573-884-4752

Functional genomics of plant-microbe interactions and plant development.

Development and application of large-scale biochemical profiling with a personal emphasis on plant specialized metabolism.

Neurodegenerative diseases, signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds.

X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.

Proteomics and phosphoproteomics of seed development and metabolism in oilseeds.

Mechanistic enzymology applied to agriculturally and medically important enzymes.

Transcriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

Environmental microbiology; bioremediation of toxic metal; genetics and biochemistry of sulfate-reducing bacteria.

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

Consultation of microscopy methods

MAP kinases in plant immunity and growth/development.

Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.

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Alphabetical listing | Biochemistry | University of Missouri