CAMBRIDGE, Mass.--(BUSINESS WIRE)--Atavistik Bio, a pre-clinical biotechnology company that is leveraging their scalable and systematic platform to identify novel regulatory sites on proteins to restore function in disease, announced the formation of its Scientific Advisory Board (SAB) comprised of distinguished leaders in protein sciences, inborn errors of metabolism, and cancer.
We are proud and honored to have these accomplished scientific leaders join our Scientific Advisory Board, said Marion Dorsch, President and CSO of Atavistik Bio. Together, they bring a wealth of knowledge and experience for Atavistik Bio as we leverage our powerful screening and analytics platforms to unlock the potential of protein-metabolite interactions with the goal to bring transformative therapies to patients. Atavistik Bio looks forward to the input of these outstanding scientists and their contribution to our research and development efforts. Feedback and collaboration with our SAB will be critical to advance our efforts to develop therapies to patients in need. It is a very exciting time for all of us at Atavistik Bio.
The founding members of the Atavistik Bio Scientific Advisory Board are:
Dr. Ralph DeBerardinis is Chief of Pediatric Genetics and Metabolism at UT Southwestern Medical Center (UTSW) and Director of the Genetic and Metabolic Disease Program at Childrens Medical Center Research Institute at UTSW (CRI). His laboratory studies the role of altered metabolic pathways in human diseases, including cancer and pediatric inborn errors of metabolism. Work from the DeBerardinis laboratory has produced new insights into disease mechanisms in numerous metabolic diseases, including by defining unexpected fuel preferences in human cancer and uncovering new metabolic vulnerabilities in cancer cells. Dr. DeBerardinis is a Howard Hughes Medical Institute Investigator and has received numerous awards including the William K. Bowes, Jr. Award in Medical Genetics, the National Cancer Institutes Outstanding Investigator Award, The Academy of Medicine, Engineering & Science of Texass Edith and Peter ODonnell Award in Medicine, and the Paul Marks Prize for Cancer Research from Memorial Sloan Kettering Cancer Center. He has been elected to the National Academy of Medicine and the Association of American Physicians.
Dr. DeBerardinis received a BS in Biology from St. Josephs University in Philadelphia before earning MD and PhD degrees from the University of Pennsylvanias School of Medicine. He completed his medical residency and post-doctoral training at The Childrens Hospital of Philadelphia (CHOP) in Pediatrics, Medical Genetics and Clinical Biochemical Genetics.
Dr. Jared Rutter is a Distinguished Professor of Biochemistry and holds the Dee Glen and Ida Smith Endowed Chair for Cancer Research at the University of Utah where he has been on the faculty since 2003. His laboratory has identified the functions of several previously uncharacterized mitochondrial proteins, including the discovery of the long-sought mitochondrial pyruvate carrier. This knowledge has demonstrated that this critical metabolic step is impaired in a variety of human diseases, including cancer and cardiovascular disease. In addition, the Rutter lab is taking multiple approaches to understand how metabolic state influences cell fate and cell behavior decisions. Dr. Rutter has been an Investigator of the Howard Hughes Medical Institute since 2015 and serves as co-Director of the Diabetes and Metabolism Center at the University of Utah and co-Leader of the Nuclear Control of Cell Growth and Differentiation at Huntsman Cancer Institute.
Dr. Rutter performed undergraduate studies at Brigham Young University and received his PhD from the University of Texas Southwestern Medical Center in 2001, working with Dr. Steve McKnight. After receiving his PhD, he spent 18 months as the Sara and Frank McKnight Independent Fellow of Biochemistry before joining the faculty at the University of Utah.
Karen Allen, Ph.D. is Professor and Chair of Chemistry at Boston University. For over 25 years, she has led research teams at Boston University, in the Departments of Physiology and Biophysics at the School of Medicine, and Chemistry. She is also a Professor of Material Science and Engineering and on the faculty of the Bioinformatics program at Boston University. The structure-aided design approach in the Allen lab encompasses the use of macromolecular X-ray crystallography, small-angle X-ray scattering, molecular modeling, and kinetics.
Karen received her B.S. degree in Biology, from Tufts University and her Ph.D. in Biochemistry from Brandeis University in the laboratory of the mechanistic enzymologist, Dr. Robert H. Abeles. Following her desire to see enzymes in action she pursued X-ray crystallography during postdoctoral studies as an American Cancer Society Fellow in the laboratory of Drs. Gregory A. Petsko and Dagmar Ringe.
Kivanc Birsoy, Ph.D. is a Chapman-Perelman Associate Professor at Rockefeller University. His research at Rockefeller focuses on how cancer cells rewire their metabolic pathways to adapt to environmental stresses during tumorigenesis and other pathological states. He is the recipient of numerous awards, including the Leukemia and Lymphoma Society Special Fellow award, Margaret and Herman Sokol Award, NIH Career Transition Award, Irma Hirschl/Monique Weill-Caulier Trusts Award, Sidney Kimmel Cancer Foundation Scholar Award, March of Dimes Basil OConnor Scholar Award, AACR NextGen award for Transformative Cancer Research, Searle Scholar, Pew-Stewart Scholarship for Cancer Research and NIH Directors New Innovator Award.
Kivanc received his undergraduate degree in Molecular Genetics from Bilkent University in Turkey in 2004 and his Ph.D. from the Rockefeller University in 2009, where he studied the molecular genetics of obesity in the laboratory of Jeffrey Friedman. In 2010, he joined the laboratory of David Sabatini at the Whitehead Institute of Massachusetts Institute of Technology (MIT) where he combined forward genetics and metabolomics approaches to understand how different cancer types rewire their metabolism to adapt nutrient deprived environments.
Benjamin Cravatt, Ph.D. is the Gilula Chair of Chemical Biology and Professor in the Department of Chemistry at The Scripps Research Institute. His research group develops and applies chemical proteomic technologies for protein and drug discovery on a global scale and has particular interest in studying biochemical pathways in cancer and the nervous system. His honors include a Searle Scholar Award, the Eli Lilly Award in Biological Chemistry, a Cope Scholar Award, the ASBMB Merck Award, the Wolf Prize in Chemistry, and memberships in the National Academy of Sciences, National Academy of Medicine, and American Academy of Arts and Sciences. Ben is a co-founder of several biotechnology companies, including Activx Biosciences (acquired by Kyorin Pharmaceuticals), Abide Therapeutics (acquired by Lundbeck Pharmaceuticals), Vividion Therapeutics (Acquired by Bayer Pharmaceuticals), Boundless Bio, Kisbee Therapeutics, and Kojin Therapeutics.
Ben obtained his undergraduate education at Stanford University, receiving a B.S. in the Biological Sciences and a B.A. in History. He then received a Ph.D. from The Scripps Research Institute (TSRI) in 1996, and joined the faculty at TSRI in 1997.
The SAB will be co-chaired by Dr. DeBerardinis and Dr. Rutter, the scientific founders of Atavistik Bio, and work closely with the company to advance their leading-edge metabolite protein screening platform discovery programs. Im delighted to be appointed Co-Chair of Atavistik Bios Scientific Advisory Board, and to be part of such a distinguished group of experts, said Dr. DeBerardinis. Together we aim to guide Atavistik Bio through the development of its pipeline while maximizing the potential of the companys technology platform, stated Dr. Rutter.
About Atavistik Bio
Atavistik Bio is a pre-clinical biotechnology company that is harnessing the power of protein-metabolite interactions to add a new lens to drug discovery with the aim of transforming the lives of patients. By leveraging its optimized Atavistik Metabolite Protein Screening (AMPS) platform and computational approaches, Atavistik Bio aims to evaluate metabolite-protein interactions by screening proteins with their proprietary metabolite library to determine where binding sites with biological relevance might exist. This will enable Atavistik Bio to build an extensive protein-metabolite database map (the Interactome) to reveal unique insights into the crosstalk between metabolite-protein pathways that were previously thought to be unrelated. Utilizing advanced informatics tools, deep expertise in chemistry and computationally rich structure-based drug design, Atavistik Bio will be able to identify and understand the role of these interactions across important biological and disease-relevant pathways to drive the discovery of novel therapeutics with an initial focus on inborn errors of metabolism and cancer. Atavistik Bio is located in Cambridge, Massachusetts. For more information, visit http://www.atavistikbio.com.
Continued here:
Atavistik Bio Announces Formation of Scientific Advisory Board - Business Wire
- Biochemistry senior connects with community through service organizations - University of South Carolina - November 28th, 2024 [November 28th, 2024]
- 2025 Summer Intern - Peptide Therapeutics, Early Discovery Biochemistry - Genentech - November 28th, 2024 [November 28th, 2024]
- Postdoctoral Position in Structural Biology/Biochemistry - Helsinki, Finland job with UNIVERSITY OF HELSINKI | 384233 - Times Higher Education - November 28th, 2024 [November 28th, 2024]
- Neugebauer named Rose Professor of Molecular Biophysics and Biochemistry - Yale News - November 28th, 2024 [November 28th, 2024]
- Scholarship has Timmins biochemistry student hopeful for the future - TimminsToday - November 20th, 2024 [November 20th, 2024]
- Lu Bai named Verne M. Willaman Professor of Biochemistry and Molecular Biology - Penn State University - November 12th, 2024 [November 12th, 2024]
- Biochemistry and biotechnology major Jay King nearing graduation with plans to pursue PhD in oncologic research - UMSL Daily - November 12th, 2024 [November 12th, 2024]
- A Biochemistry Teaching Experiment That Demonstrates the Digestion of Carbohydrates, Proteins, and Lipids in the Digestive Tract - ACS Publications - November 12th, 2024 [November 12th, 2024]
- SBU Biochemistry alumnus to discuss how plants defend themselves against bacterial pathogens - St. Bonaventure - October 13th, 2024 [October 13th, 2024]
- Exploring the Frontiers of Metabolic Research in Cancer: An Interview with Dr. Alice Chang, B. Pharm., Ph.D. at China Medical University, Institute of... - October 2nd, 2024 [October 2nd, 2024]
- The Hidden Biochemistry of Cold Temperatures: Chilling RNA Discovery Reshapes the Rules of Life - SciTechDaily - September 23rd, 2024 [September 23rd, 2024]
- New sweatband keeps tabs on body biochemistry - The Naked Scientists - September 15th, 2024 [September 15th, 2024]
- Celebrating 25 years of innovation at the department of biochemistry & medical genetics - UM Today - September 15th, 2024 [September 15th, 2024]
- Vinesh Phogat versus the perplexing biochemistry of losing weight - The Hindu - September 2nd, 2024 [September 2nd, 2024]
- Girirajan named head of the Department of Biochemistry and Molecular Biology - Penn State University - July 26th, 2024 [July 26th, 2024]
- Scientists uncover a multibillion-year epic written into the chemistry of life - EurekAlert - June 1st, 2024 [June 1st, 2024]
- Electrolyte and Biochemistry Analyzers Market Is Likely to Experience a Tremendous Growth by 2031 - openPR - June 1st, 2024 [June 1st, 2024]
- Scientists uncover missing link in the Chemistry of Life - Tech Explorist - June 1st, 2024 [June 1st, 2024]
- From negative results to new discoveries in chloroplast biochemistry - Phys.org - April 15th, 2024 [April 15th, 2024]
- Protecting art and passwords with biochemistry - Tech Xplore - April 15th, 2024 [April 15th, 2024]
- 'Always more to discover:' Clarke biochemistry professor shares love of the Bard through Dubuque Shakespeare Project - telegraphherald.com - April 15th, 2024 [April 15th, 2024]
- American Society of Biochemistry and Molecular Biology honors MD/PhD student Hannah Kondolf - The Daily | Case Western Reserve University - April 7th, 2024 [April 7th, 2024]
- Biochemistry and transcriptomic analyses of Phthorimaea absoluta (Lepidoptera: Gelechiidae) response to insecticides ... - Nature.com - April 7th, 2024 [April 7th, 2024]
- Differential responses of Hollyhock (Alcea rosea L.) varieties to salt stress in relation to physiological and biochemical ... - Nature.com - April 7th, 2024 [April 7th, 2024]
- Life's Origins: How Fissures in Hot Rocks May Have Kickstarted Biochemistry - Singularity Hub - April 7th, 2024 [April 7th, 2024]
- Professor Robert Cross awarded Biochemical Society Award for Sustained Excellence - University of Warwick - April 7th, 2024 [April 7th, 2024]
- Study suggests that estrogen may drive nicotine addiction in women - EurekAlert - March 29th, 2024 [March 29th, 2024]
- Yale men's basketball confused for university's Molecular Biophysics and Biochemistry on Twitter - Sporting News - March 29th, 2024 [March 29th, 2024]
- Plants have an astonishing biochemical communication network - Earth.com - March 29th, 2024 [March 29th, 2024]
- Study links long-term consumption of deep-fried oil with increased neurodegeneration - ASBMB Today - March 29th, 2024 [March 29th, 2024]
- New surfactant could improve lung treatments for premature babies - ASBMB Today - March 29th, 2024 [March 29th, 2024]
- The Power and Promise of RNA - Duke University School of Medicine - March 29th, 2024 [March 29th, 2024]
- Commonwealth University biochemistry and pre-medicine concentrations accredited - Lock Haven Express - February 13th, 2024 [February 13th, 2024]
- Afternoon of Science Series: Department of Biochemistry & Molecular Biophysics - Columbia University Irving Medical Center - February 13th, 2024 [February 13th, 2024]
- What Casual Sex, Pigeon Relationships, Bioluminescence and a Drug for Broken Hearts can Tell us About the ... - Nautilus - February 13th, 2024 [February 13th, 2024]
- $2.4 Million in Funding Awarded to Chemistry and Biochemistry Faculty | CSUF News - CSUF News - February 13th, 2024 [February 13th, 2024]
- Associate Professor in Biochemistry and Director of NIH-Funded COBRE job with UNIVERSITY OF NEW HAMPSHIRE ... - Nature.com - February 13th, 2024 [February 13th, 2024]
- USM Chemistry (Biochemistry Emphasis) Degree Earns ASBMB Reaccreditation - The University of Southern Mississippi - February 4th, 2024 [February 4th, 2024]
- AI generates proteins with exceptional binding strength - ASBMB Today - February 4th, 2024 [February 4th, 2024]
- A safe place where biochemistry is valued - ASBMB Today - October 27th, 2023 [October 27th, 2023]
- Chair (W3) of Biochemistry job with TECHNISCHE UNIVERSITAT ... - Times Higher Education - October 27th, 2023 [October 27th, 2023]
- The Biochemistry of Muscle Contraction - Discovery Institute - October 27th, 2023 [October 27th, 2023]
- Department of Biochemistry and Molecular Biology chair and ... - University of Iowa Health Care - October 27th, 2023 [October 27th, 2023]
- Two decorated Brandeis faculty awarded National Medal of Science ... - Brandeis University - October 27th, 2023 [October 27th, 2023]
- Research Assistant / Associate (Department of Biochemistry) job ... - Times Higher Education - October 27th, 2023 [October 27th, 2023]
- ASBMB weighs in on policy changes for dual-use research - ASBMB Today - October 27th, 2023 [October 27th, 2023]
- In the Locker Room with Katie Austin, Mia Brito, and Alaina Di Dio ... - The Oberlin Review - October 27th, 2023 [October 27th, 2023]
- Dr. Tara Schwetz named NIH Deputy Director for Program ... - National Institutes of Health (.gov) - October 27th, 2023 [October 27th, 2023]
- Armstrong Welcomes Burning Swamp The George-Anne Media ... - The George-Anne - October 27th, 2023 [October 27th, 2023]
- Summer Research Projects Grow Depth of Knowledge - Taylor University - October 27th, 2023 [October 27th, 2023]
- Brookings Register | Speakout: Decarbonize industry with nuclear ... - Brookings Register - October 27th, 2023 [October 27th, 2023]
- Professor Yong Sik Ok becomes the first Korean President of the ... - EurekAlert - October 27th, 2023 [October 27th, 2023]
- Partnership between UCR and City of Hope aims to increase ... - UC Riverside - October 27th, 2023 [October 27th, 2023]
- The seeds have been planted: The beautification of Ernst Nature ... - Miami Student - October 27th, 2023 [October 27th, 2023]
- Biochemist selected as Innovation Fund investigator by Pew ... - Pennsylvania State University - October 27th, 2023 [October 27th, 2023]
- UTHealth Houston researchers awarded $3.4M NIH grant to study ... - EurekAlert - October 27th, 2023 [October 27th, 2023]
- Centre professor, students working toward rapid, affordable ... - Danville Advocate - October 27th, 2023 [October 27th, 2023]
- SUNY Potsdam faculty want to keep 13 of 14 programs eyed for cuts ... - The Adirondack Daily Enterprise - October 27th, 2023 [October 27th, 2023]
- Fall Awards recognize long years of service to UWM - University of WisconsinMilwaukee - October 27th, 2023 [October 27th, 2023]
- Shobade selected for inaugural innovation in agriculture award - College of Agriculture and Life Sciences - April 8th, 2023 [April 8th, 2023]
- Three juniors selected as Goldwater Scholars - The Source ... - Washington University in St. Louis - April 8th, 2023 [April 8th, 2023]
- Senior Awarded Fulbright to Germany Susquehanna University - Susquehanna University - April 8th, 2023 [April 8th, 2023]
- CI MED Students Win Top Honors At Startup Showcase at ... - Carle Illinois College of Medicine - April 8th, 2023 [April 8th, 2023]
- Gregory Bowman: Penn Integrates Knowledge University Professor ... - University of Pennsylvania - April 8th, 2023 [April 8th, 2023]
- The Columns W&L's Jaden Keuhner '24 Featured in WSLS 10 ... - The Columns - April 8th, 2023 [April 8th, 2023]
- New anticancer agent activated by ultrasound waves does not have strong side effects - News-Medical.Net - April 8th, 2023 [April 8th, 2023]
- Obituary for Alison Lynn Smoot-Pierce, Conway, SC - Arkansas Online - April 8th, 2023 [April 8th, 2023]
- Finding a way to combat long COVID - EurekAlert - April 8th, 2023 [April 8th, 2023]
- High schoolers awarded for action research | Sioux Center News - nwestiowa.com - April 8th, 2023 [April 8th, 2023]
- Emory researchers discover key pathway for COVID-19 organ ... - Emory News Center - April 8th, 2023 [April 8th, 2023]
- Auburn chemistry graduate student shines as only Southeastern ... - Office of Communications and Marketing - April 8th, 2023 [April 8th, 2023]
- Study uncovers aspect of how muscular dystrophies progress - ASBMB Today - April 8th, 2023 [April 8th, 2023]
- Broccoli intake protects the small intestine lining, inhibits development of disease - News-Medical.Net - April 8th, 2023 [April 8th, 2023]
- The Greek who gave $600 million to education - Kathimerini English Edition - April 8th, 2023 [April 8th, 2023]
- Man linked to firebombing of Wisconsin anti-abortion group via leftover burrito - Yahoo News - April 8th, 2023 [April 8th, 2023]
- Important enzyme for the composition of the gut microbiome discovered - Phys.org - April 8th, 2023 [April 8th, 2023]
- Unraveling the protein map of cell's powerhouse - ASBMB Today - April 8th, 2023 [April 8th, 2023]
- Celebrating undergrad thesis research at Barrett, The Honors ... - ASU News Now - April 8th, 2023 [April 8th, 2023]
- NSCBMC Recruitment 2023: Check Posts, Qualification and How to ... - StudyCafe - April 8th, 2023 [April 8th, 2023]
- Taking a first bite of biochemistry - ASBMB Today - March 23rd, 2023 [March 23rd, 2023]