After decades of playing second fiddle, computation is now taking center stage achieving critical insights that experimentation alone cannot provide. We are witnessing a dramatic rise in artificial intelligencebased methods coupled with year-on-year improvements of physics-based approaches. We now can fold a protein accurately from sequence alone!

Game-changing methods in protein and enzyme design are hurtling toward us. Scientists now can integrate numerous experimental data sets into computational models to explore previously unseen elements at (and across) scales never before achieved. Computational simulations are rewriting textbooks from molecules to system dynamics and function. Machine learning is transforming drug design and development.

All in all, you will not find a symposium at Discover BMB, the annual meeting of the American Society for Biochemistry and Molecular Biology, filled with more excitement and possibility than ours. Buckle up for a thrilling ride in March in Seattle!

Keywords: Artificial intelligence, structural biology, simulation, drug discovery, bioinformatics, systems biology, machine learning.

Who should attend: All who want to find out how computation is transforming biological problem-solving.

Theme song: Respect by Aretha Franklin, because computation deserves it.

This session is powered by a powerful flux capacitor.

Structure determinationDebora Marks,Harvard Medical SchoolRommie E. Amaro (chair),University of California, San DiegoRamanathan Arvind,Argonne National Laboratory; University of ChicagoJason Perry,Gilead Sciences Inc.

Drug designJohn Chodera,Sloan Kettering InstituteDavid Baker,University of WashingtonSteve Capuzzi,Vertex PharmaceuticalsCelia Schiffer (chair),University of Massachusetts Chan Medical School

Bioinformatics / Systems biologyMarian Walhout,University of Massachusetts Chan Medical SchoolJanet George,Intel CorporationIvet Bahar (chair),University of Pittsburgh School of MedicineHenry van dem Bedam,AtomWise Inc.

Originally posted here:
Computation is the new experiment - ASBMB Today