If youre a regular reader of Nanalyze, youll know that were big fans of the work that Bryan Johnson of Kernel is doing, essentially trying to enable read/write access to the brain. In one of his interviews, he remarks thatever since we first booted up a cell with human engineered DNA, we entered a new era that according to his mentor Peter Diamandis 99.9% of people have no idea weve entered.

What theyre referring to is the fact that humans have essentially discoveredthe Engines of Creation that Eric Drexler was talking about. While everyone is running around slinging political mud at each other like a bunch of primitive monkeys, mankind is working on one of the most transformational technologies that may ever be invented. Its called synthetic biology and its why everyone should have a basic understanding of biochemistry.

When you werechoosing your major in college, you either had your mind set on a particular field already or you needed to peruse all thesubject areas to see what sounded like a good fit. Each subject area will have a certain stereotype associated with it.Some fields sound boring like electrical engineering or accounting. Some fields sound inherently difficult, like physics or mathematics. Other fieldsyou may not have an idea of what they do because they never sounded compelling enough to research. Thats the case for us withbiochemistry and thats why we thought as investors we should edify ourselves on what turned out to be a very relevant and interesting area of the sciences.

If we lookup the basic definition of biochemistry, this is what we get:

the branch of science concerned with the chemical and physico-chemical processes and substances which occur within living organisms.

So its a bit different from chemistry since itsall about the study of chemical processes in living organisms. Heres why it came about according to the American Chemical Society:

Biochemistry emerged as a separate discipline when scientists combined biology with organic, inorganic, and physical chemistry and began to study how living things obtain energy from food, the chemical basis of heredity, what fundamental changes occur in disease, and related issues.

The most basic premise is that you are using living things to take INPUT X and turn it into OUTPUT Y in the most efficient manner possible. If you think about humans as a complex organism, we are able to utilize the equivalent of several pounds of vegetative material to power one of the most complex and amazing machines on the planet. The problem with us though, is that the output from that process has no real use except maybe as fertilizer.

In the U.S. alone, there are approximately 13,500 chemical manufacturing facilities in the United States owned by more than 9,000 companies. These are giant operations which consume a great deal of energy, require a large workforce to maintain, and generate a great deal of pollution. Imagine how much energy and effort goes into building compex mechanical contraptions like this:

Your bog standard chemicals plant

Think about how inefficient these plants have been over the decades theyve sat there consuming resources and feeding the mass consumerism that we enjoy in todays modern society.Now think about this. What if instead of using these inneficient plants, we engineered biological organisms to produce chemicals by modifying the DNA of the organisms so they did what we needed.The simplest way to think about it is to visualize those punch-cards we used our dads used back in the day. If thats beyond your time, heres what an IBM punch card used to look like:

In the olden days of mainframe computing, we used apunch card like the ones seen above toprovide the computer with a set of instructions. With DNA, its pretty much the same idea except its like havingprecisely this many punch cards:

The above pile of phone books shows roughly the amount of data that a strand of DNA contains, approximately 700gigabytes of data. DNA is one giant punch card that just recently weve been given the hole punch for. That hole punch is called gene editing and its been all over the news lately due to a nasty lawsuit that will determine who has the commercial rights to one of the most exciting discoveries known to man. This biological hole punch called CRISPR will soon let us change every single characteristic we like for any organism and then boot it up so we have our own little biological nanobots doing things for us.Since organisms are the most efficient biological factories (or engines of creation) known to man, it makes sense that we should be modifying them to produce as many industrial chemicals as possible.

The use of synthetic biology for creating things like biofuels (primarily)was off to a rough start as evidenced by the cratering stocks involved in this space like Amyris (NASDAQ:AMRS) and Gevo (NASDAQ:GEVO). Fast forward to today and the potential is even greater but a different model is now being applied. Now you have nanobot factories like Ginkgo Bioworks and Zymergen that areusing artificial intelligence, robotics, and gene editing in order to create little tiny biological chemical manufacturing plants.

Lets say youre a chemical plant that uses a particular enzyme in your production process. Ginkgo or Zymergen can take that enzyme and modify it over millions and millions of iterations. The speed at which they can modify that enzyme has just hit hockey stick growth as seen below:

The end result is an optimized enzyme that meets your requirements and saves you millions of dollars. Startups like this that are using synthetic biology to completely overhaul the industrial chemical manufacturing process are as secretive as you would expect. While we may not have detailed information about what theyre working on, we can take a look at some examples of startups that are using biochemistry and synthetic bioogyin order to create some pretty complex and useful outputs from some basic interesting inputs:

These startups are backed by some big dollars and some big names, however the future business model is a bit hazy here. Will we have the chemical companies going directly to the creators of the synthetic organisms like Ginkgo or will we have startups like the ones mentioned above doing all the production and selling to the chemical companies, only to get acquired once the technology is proven? The one thing that we can be sure of here is that the large chemical producers will profit fromthe use of biochemistry, synthetic biology, and gene editing, consequently we can expect shareholders in these companies to reap the benefits.

This morning when youre tempted to talk about how much political mudslinging there was at the Oscars or who wore the cutest dress, do the world a favor and tell someone how exciting biochemistry is instead.

Looking to buy shares in companies before they IPO?A company called Motif Investing lets you buy pre-IPO shares in companies that are led by JP Morgan. You can open an account with Motif with no deposit required so that you are ready to buy pre-IPO shares when they are offered.

Read more from the original source:
What is Biochemistry and Why it Matters - Nanalyze