April 5, 2024 Cardiawave SA, a French medtech company that has developed an innovativeNon-Invasive focused Ultrasound Therapy(NIUT) device for the treatment of severe symptomatic calcific aortic stenosis, will present the 30-day follow-up results for 60 patients enrolled in its European pivotal study to the 73rdannual conference of the American College of Cardiology in Atlanta, Georgia. This is a leading event in the cardiovascular medicine calendar, which brings together specialists from around the world to discuss the latest advances, research results and clinical innovations in the field of cardiology.

Prof. Eric Van Belle, cardiologist at Lille University Hospital, one of the principal investigators for the European pivotal study, commented: Im very proud to present the excellent results obtained using Cardiawaves NIUT device to treat patients with severe symptomatic aortic valve stenosis, leading to a significant improvement in their condition and a better quality of life.This ACC.24 presentation represents a major contribution to the advance of science and will open up innovative therapeutic strategies for cardiology patients.

A summary of the poster session will be published on theJournal of the American College of Cardiologys website.

Presentation title:QUALITY OF LIFE ASSESSMENT AT 30-DAYS FOLLOW-UP OF THEVALVOSOFTPIVOTAL STUDY ON SEVERE AORTIC VALVE STENOSE PATIENTS" (control number 16930)

Time and date: April 8, 2024 -9:32 a.m.9:42 a.m. EDT

The results of the Cardiawave First-in-Human Valvosoft FIM Study were published in The Lancetin November 2023: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01518-0/fulltext

For more information:www.cardiawave.com

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Cardiawave is Presenting the 30-day Follow-up Results from its Valvosoft Pivotal Study on the Teatment of Severe ... - Diagnostic and Interventional...