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Biochemistry Analyzers Market Overview, Industry Top Manufactures, Market Size, Industry Growth Analysis & Forecast ... - DailyNewsKs

Dr. Sharifa Love-Rutledge is a new faculty member in the UAH College of Science.

Michael Mercier | UAH

Sharifa Love-Rutledge developed a keen interest in science when she and her younger brother shared a lab kit for Christmas one year. "We made borax (super bouncy) balls first, and went on to complete all the experiments in the kit, and I wanted to do more," said Love-Rutledge, an incoming faculty member at The University of Alabama in Huntsville (UAH) College of Science. She is also the first African-American woman to earn a PhD from The University of Alabama Department of Chemistry.

When Love-Rutledge entered college, she started out as a biology major, but after completing general chemistry and organic chemistry courses, she made the "switch" to chemistry.

"I was drawn to chemistry because of my love for creative problem-solving. Biochemistry was the subject that allowed me to utilize my analytical thought processes to pursue biological questions. It didn't dawn on me that chemistry was a male dominated field until graduate school. By then, it was too late because I was already hooked."

A native of Moss Point, MS, Love-Rutledge attended Moss Point High School. An Advanced Placement student in English and Mathematics, she went on to graduate from Tougaloo College (Tougaloo, MS) with a Bachelor of Science degree in Chemistry. Love-Rutledge earned a Master's degree and PhD from The University of Alabama (UA) in Chemistry and Biochemistry, respectively.

Love-Rutledge said she "felt hopeful," when she realized she would be the first African American woman to earn a PhD in chemistry from UA. "It was bittersweet because the reality of it all is that I wasn't the first African American female capable of the accomplishment but opportunities weren't afforded in the past. It allowed me to view myself as part of the culmination of the sacrifices made by those like Vivian Malone and James Hood," she added.

The student in lockstep with Love-Rutledge in the Department of Chemistry at UA was Dr. Melody Kelley, now Assistant Professor of Chemistry at Georgia State University. Love-Rutledge said she continues to find "inspiration in seeing other African American women who are persevering and making progress toward the completion of advanced degrees."

Early mentors for Love-Rutledge were her older siblings. "They poured their knowledge into me to ensure that I made wise decisions. If it wasn't for my older brother, I don't think I would've survived some of my math courses," she said. "Once I left home, I started to rely on advice from my uncle Dr. Claude McGowan, who was Director of Toxicology at Johnson & Johnson, along with professors like Dr. Candice Love-Jackson, Acting Provost and Vice President for Academic Affairs at Kentucky State University."

Additionally, Love-Rutledge was encouraged through the graduate school application process by dedicated Ronald McNair Scholars Coordinator, Demetria Hereford. And, as a graduate student, she was able to enlist the tutelage of several professors at UA. "It was also in graduate school that I was reminded of how important my parents' guidance is. Their constant support and dedication was important in forming my personal and professional abilities."

Love-Rutledge learned about UAH from Dr. Emanuel Waddell, Associate Dean of the College of Science while attending graduate school at UA. "The deciding factors for me to further my teaching and research career at UAH included the size of the student population and access to resources that I would need to be successful. I have always wanted to work at a university where students are viewed as more than numbers."

"We are excited to have Dr. Love-Rutledge join us in the chemistry department. Her research will be attractive to students and we look forward to her establishing her research laboratory in the coming months," said Dr. Emanuel Waddell, Associate Dean of the UAH College of Science.

At UAH Love-Rutledge will teach biochemistry classes. "I have a lab and I am currently working on research projects related to identifying biomarkers for Type 1 Diabetes, and studying the changes cells producing insulin undergo before disease onset." As a teacher, Love-Rutledge said she loves students' lightbulb moments the best. At UA she served as a graduate teaching assistant for the majority of her graduate career. "I love reaffirming students' passion for their chosen field of study. There is no greater joy for me than to see my students go on to be successful in their fields of choice. I have taught students who wanted to be nurses and are nurses now, and students who wanted to be doctors who are now in residency programs. I love seeing students reach their goals."

As a Ronald E. McNair Scholar, Love-Rutledge's first bona fide research project studied the enzymes that activate colon cancer drugs. The project's Principal Investigator was Dr. Randy Wadkins, Associate Professor of Chemistry and Biochemistry at The University of Mississippi. "In my graduate research, I worked on projects that helped show Chromium, (hard, brittle metal) is not an essential element for mammalian nutrition. The research findings were published in a paper that led The European Food and Safety Authority to remove Chromium from the list of elements that 'require daily intake'."

Love-Rutledge freely offers words of wisdom for young women interested in entering academic fields of specialization. "Recently Ive been exposed to the slogan, 'You cant do UAH alone'. I think it's awesome advice for young women to adapt who are interested in chemistry 'You cant do Chemistry alone'," she said. "Even when you seem alone, you never are. Find mentors to give you advice, utilize your peers on and off campus to get through the tough times. Some of my best academic advice came from taking a risk and emailing a professor who I thought was out of reach. You will be surprised at how much help you could receive if you just ask for it."

***EDITOR'S NOTE: The McNair Scholars Program is a federal program funded at 51 institutions across the United States and Puerto Rico by the U.S. Department of Education. It is designed to prepare undergraduate students for doctoral studies through involvement in research and other scholarly activities. Dr. Ronald E. McNair was the second African American to fly in space. Two years later he was selected to serve as mission specialist aboard the ill-fated U.S. Challenger space shuttle. He was killed on Jan. 28, 1986, instantly when the Challenger exploded one minute, 13 seconds after it was launched.

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UAH welcomes Dr. Sharifa Love-Rutledge to the College of Science - UAH News (press release)

Taipei, Aug. 28 (CNA) Antibody and small molecule drugs and big data applications will remain at the center of biomedical research in the future, according to Andrew Wang (), president-elect of the International Union of Biochemistry and Molecular Biology (IUBMB).

Wang was speaking on the future development of biomedical technology in a recent interview with CNA, in which he encouraged local scientists to find the right directions if they decide to devote themselves to antibody drug research and development.

Biomedicine is an emerging sector that has attracted many scientists around the world, said the chemist, who serves as the distinguished visiting chair of the Institute of Biological Chemistry at Academia Sinica, Taiwan's top academic research institution.

Wang also encouraged researchers to seek new techniques, citing the example of French scientist Emmanuelle Charpentier and Americans Jennifer A. Doudna and Feng Zhang (), the trio who shared the 2016 Tang Prize for biopharmaceutical science.

They were honored for the development of the CRISPR/Cas9, a genome editing tool that enables geneticists and medical researchers to edit DNA, using a technique that has the potential for a wide range of applications, according to the Tang Prize Foundation.

Wang praised the CRISPR/Cas9 as a big breakthrough, and he expected it to significantly affect future research, which he said could even reach the aspect of biological transformation.

"In the future, cell therapies will become very important," Wang said.

In addition to antibody and small molecule drug research, changes in medical treatment methods are a direction that local scientists can also turn to, Wang said, noting that the results of big data analysis related to health insurance practices can be applied in the precision medicine sector.

The Tang Prize awards were established by Taiwanese entrepreneur Samuel Yin () in 2012 to honor people who have made significant contributions in the fields of sustainable development, biopharmaceutical science, sinology and rule of law. They are dubbed as the "Asian Nobel Prize."

The IUBMB is an international non-governmental organization concerned with biochemistry and molecular biology. Founded in 1955, it unites biochemists and molecular biologists in 75 countries that belong to the union as an adhering body or associate adhering body represented by a biochemical society, a national research council or an academy of sciences.

(By Yu Hsiao-han and Elizabeth Hsu)Enditem/sc

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Scientist expects biomed research to remain focused on antibodies - Focus Taiwan News Channel

Madeleine Gerrie of Sydney has been named this years recipient of the Sara March Memorial Educational Award handed out by the United Heritage Church in Sydney. Gerrie, who is studying biochemistry at Waterloo University, is shown with her younger sister, Naomi.

Submitted photo/Madeleine Gerrie

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Sydney student receives Sara March bursary - Cape Breton Post

Palestinian cancer patients in Gaza City protest Israels restrictions on travel for treatment, December 2016. Such restrictions are partly why academics are calling on colleagues to boycott Septembers Federation of European Biochemical Societies conference in Jerusalem.

Palestinian, Israeli and international academics are urging colleagues to boycott the 2017 congress of the Federation of European Biochemical Societies in Jerusalem next month.

Some attendees will be unaware of Israels direct attacks on Palestinians right to education, including the bombing of schools and universities, and the obstruction of access to educational sites, the scientists and academics write in a letter that has been sent to all conference speakers.

The restrictions Israel places on the teaching and research of our Palestinian colleagues have severe consequences not only on research and educational opportunities, but also on Palestinians health.

The 89 scholars calling for the boycott include researchers from leading institutions across Europe and North America.

Even though no country recognizes Israels claim to sovereignty over Jerusalem, the Federation of European Biochemical Societies conference website prominently advertises its location as Jerusalem, Israel.

It also locates the occupied Golan Heights Syrian territory as part of Israel.

Whether intentional or not, this makes the academic body a direct participant in Israels efforts to legitimize its violent occupation, annexation and colonization of these territories in violation of international law.

The conference is sponsored by several Israeli universities that are directly complicit in Israeli violations of Palestinian rights, including weapons development, support for Israels attacks on Gaza and helping recruitment for Israels secret police.

Israeli universities are also directly involved in efforts to undermine international solidarity for Palestinian rights.

The Association of University Heads of Israel, for instance, is known to help the Israeli governments efforts to censor teaching about Palestine in universities in other countries and to try to thwart the global Palestinian rights movement.

One of the themes of the conference is the biochemistry of cancer. Rates of cancer are rising, particularly for Palestinians in the blockaded Gaza Strip.

But as the scholars point out, Israel actively obstructs life-saving treatment: The five-year survival rate for breast cancer is as low as 30 percent in Gaza, which Israel has besieged for the past 10 years, as compared to 86 percent in Israel. In 2016, only 44 percent of Gaza patients who requested access to Israeli hospitals were admitted; more than half of those refused entry were cancer patients.

Meanwhile, the health system in Gaza is at the brink of collapse due to Israels severe reductions in the energy supply to the territory.

Anticipating typical arguments against the boycott, the scholars state: To be clear, the academic boycott of Israel that Palestinians have called for respects the universal principle of academic freedom as it is only directed at Israeli institutions, not individual academics. Despite the differences, it is inspired by the academic boycott of South Africa, which was called for in 1965 by 496 academics from 34 universities in the United Kingdom.

Last year, after a similar appeal, several scholars pulled out of a conference on genocide hosted by Hebrew University.

Israeli university leaders have said that they are being hit hard by a silent boycott, where many academics stay away from Israeli institutions but do not make any public statement.

Leading Israel lobby groups have also acknowledged the growing impact of the so-called silent boycott.

The scholars note that the Federation of European Biochemical Societies has itself been sensitive to political concerns regarding the location of its conferences. In 2016, the body expressed solidarity with the Turkish scientific community facing curtailment of academic freedoms in Turkey, and subsequently canceled its conference scheduled to take place there.

By organizing its congress in Jerusalem, the FEBS participates consciously or unconsciously in whitewashing Israels violent repression of Palestinian human rights, said Ahmed Abbes, research director at Frances CNRS scientific institute, and secretary of AURDIP, an academic group that supports Palestinians rights.

We hope that our colleagues will take the opportunity of consulting their consciences, listen to the voice of Palestinian civil society, and decline to cross this picket line.

Originally posted here:
Scientists urged to boycott Israel biochemistry conference - The Electronic Intifada (blog)

Biochemistry - Part I Moof UniversityMoof University Acids, Bases, and the Henderson-Hasselbalch EquationAmino AcidsProtein Structure and FunctionCarbohydratesEnzymesEnzyme InhibitionEnzyme RegulationBiochemist's Toolbox - Learn These BEFORE Learning Glycolysis and Other PathwaysGlycolysisGluconeogenesisGlycogenTCA / Krebs / Citric Acid CycleGlycolysis Energy CalculationsElectron Transport ChainPhotosynthesisPentose Phosphate PathwayLipidsFatty Acid MetabolismKetone BodiesFatty Acid SynthesisLipid SynthesisCholesterol SynthesisRegulation of Cholesterol SynthesisLipoproteins

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Biochemistry - Part I Moof University

In 2013, University of Virginia researcher Michael McConnell published research that would forever change how scientists study brain cells.

McConnell and a team of nationwide collaborators discovered a genetic mosaic in the brains neurons, proving that brain cells are not exact replicas of each other, and that each individual neuron contains a slightly different genetic makeup.

McConnell, an assistant professor in the School of Medicines Department of Biochemistry and Molecular Genetics, has been using this new information to investigate how variations in individual neurons impact neuropsychiatric disorders like schizophrenia and epilepsy. With a recent $50,000 grant from the Bow Foundation, McConnell will expand his research to explore the cause of a rare genetic disorder known as GNAO1 so named for the faulty protein-coding gene that is its likely source.

GNAO1 causes seizures, movement disorders and developmental delays. Currently, only 50 people worldwide are known to have the disease. The Bow Foundation seeks to increase awareness so that other probable victims of the disorder can be properly diagnosed and to raise funds for further research and treatment.

UVA Today recently sat down with McConnell to find out more about how GNAO1 fits into his broader research and what his continued work means for all neuropsychiatric disorders.

Q. Can you explain the general goals of your lab?

A. My lab has two general directions. One is brain somatic mosaicism, which is a finding that different neurons in the brain have different genomes from one another. We usually think every cell in a single persons body has the same blueprint for how they develop and what they become. It turns out that blueprint changes a little bit in the neurons from neuron to neuron. So you have slightly different versions of the same blueprint and we want to know what that means.

The second area of our work focuses on a new technology called induced pluripotent stem cells, or iPSCs. The technology permits us to make stem cell from skin cells. We can do this with patients, and use the stem cells to make specific cell types with same genetic mutations that are in the patients. That lets us create and study the persons brain cells in a dish. So now, if that person has a neurological disease, we can in a dish study that persons disease and identify drugs that alter the disease. Its a very personalized medicine approach to that disease.

Q. Does cell-level genomic variety exist in other areas of the body outside the central nervous system?

A. Every cell in your body has mutations of one kind or another, but brain cells are there for your whole life, so the differences have a bigger impact there. A skin cell is gone in a month. An intestinal cell is gone in a week. Any changes in those cells will rarely have an opportunity to cause a problem unless they cause a tumor.

Q. How does your research intersect with the goals of the Bow Foundation?

A. Let me back up to a little bit of history on that. When I got to UVA four years ago, I started talking quite a lot with Howard Goodkin and Mark Beenhakker. Mark is an assistant professor in pharmacology. Howard is a pediatric neurologist and works with children with epilepsy. I had this interest in epilepsy and UVA has a historic and current strength in epilepsy research.

We started talking about how to use iPSCs the technology that we use to study mosaicism to help Howards patients. As we talked about it and I learned more about epilepsy, we quickly realized that there are a substantial number of patients with epilepsy or seizure disorders where we cant do a genetic test to figure out what drug to use on those patients.

Clinical guidance, like Howards expertise, allows him to make a pretty good diagnosis and know what drugs to try first and second and third. But around 30 percent of children that come in with epilepsy never find the drug that works, and theyre in for a lifetime of trial-and-error. We realized that we could use iPSC-derived neurons to test drugs in the dish instead of going through all of the trial-and-error with patients. Thats the bigger project that weve been moving toward.

The Bow Foundation was formed by patient advocates after this rare genetic mutation in GNAO1 was identified. GNAO1 is a subunit of a G protein-coupled receptor; some mutations in this receptor can lead to epilepsy while others lead to movement disorders.

Were still trying to learn about these patients, and the biggest thing the Bow Foundation is doing is trying to address that by creating a patient registry. At the same time, the foundation has provided funds for us to start making and testing iPSCs and launch this approach to personalized medicine for epilepsy.

In the GNAO1 patients, we expect to be able to study their neurons in a dish and understand why they behave differently, why the electrical activity in their brain is different or why they develop differently.

Q. What other more widespread disorders, in addition to schizophrenia and epilepsy, are likely to benefit from your research?

A. Im part of a broader project called the Brain Somatic Mosaicism Network that is conducting research on diseases that span the neuropsychiatric field. Our lab covers schizophrenia, but other nodes within that network are researching autism, bipolar disorder, Tourette syndrome and other psychiatric diseases where the genetic cause is difficult to identify. Thats the underlying theme.

Continue reading here:
Researcher Seeks to Unravel the Brain's Genetic Tapestry to Tackle Rare Disorder - University of Virginia

The public's help is being enlisted in the Microbiome Immunity Project, what's thought to be the biggest study to date of the human microbiome the communities of bacteria and other microbes that live in and on the human body, where they influence our health.

Since studying the entire human microbiome would be almost impossible with traditional methods, massive supercomputing processing power is being crowdsourced via IBM's World Community Grid. Volunteers download a secure software program that automatically detects when a computer can offer spare processing power, then taps it to run virtual experiments on behalf of researchers. Anyone with a computer and an internet connection can join the World Community Grid and sign up to support the Microbiome Immunity Project at http://www.worldcommunitygrid.org

The project is co-led by Rob Knight, PhD, professor of pediatrics at University of California San Diego School of Medicine and director of the Center for Microbiome Innovation at UC San Diego, with collaborators at Broad Institute of Harvard and MIT, Massachusetts General Hospital and Simons Foundations Flatiron Institute. At UC San Diego, Tomasz Kosciolek, PhD, a postdoctoral researcher in Knights lab, Rommie Amaro, PhD, professor of chemistry and biochemistry, and Bryn Taylor, a graduate student mentored by Knight and Amaro, are also involved in the project.

The team will use the surplus processing power on World Community Grid volunteers' computers to conduct millions of virtual experiments. They aim to map 3 million bacterial genes found in the human microbiome and predict the structure of their associated proteins.

The studys goal is to help scientists better understand the microbiomes interaction with human biochemistry and determine how that interaction may contribute to autoimmune diseases, such as type 1 diabetes, Crohns disease and ulcerative colitis. With better understanding, scientists might be able to more easily prevent and treat these diseases. The researchers will make their data publicly available to other scientists, accelerating the advancement of scientific knowledge in this important area of research.

Had World Community Grid not existed, we wouldn't have even contemplated this project, Knight said. By harnessing the efforts of volunteers, we can do something that exceeds the scale of what we have access to by a factor of thousands. For the first time, we're bringing a comprehensive structural biology picture to the whole microbiome, rather than solving structures one at a time in a piecemeal fashion.

Since its founding in 2004, World Community Grid has supported 29 research projects on cancer, HIV/AIDS, Zika, clean water, renewable energy and other humanitarian challenges. To date, World Community Grid, hosted on IBM Cloud, has connected researchers to $500 million U.S. dollars' worth of free supercomputing power. More than 730,000 individuals and 430 institutions from 80 countries have donated more than one million years of computing time from more than three million computers and Android devices. Volunteer participation has helped researchers to identify potential treatments for childhood cancer, more efficient solar cells and more efficient water filtration.

UC San Diego researchers are also involved in OpenZika, a World Community Grid project launched in May 2016 which aims to identify drug candidates to combat the Zika virus.

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Help UC San Diego Scientists Study Link between Body Bacteria and Autoimmune Diseases - UC San Diego Health

Mr. and Mrs. L. Abraham Rowe Jr. of Brandon announces the engagement of their daughter, Rhea Kay Rowe, to Luke F. Hartje of Ft. Collins, Colo.

The brideelect is the granddaughter of John and Margaret McAleese of Brandon and Lawrence and the late Carolyn Rowe of Clinton. The prospective bridegroom is the son of Kevin and Deena Hartje of Colorado Springs, and the grandson of Jean and the late Fred Skaro of Grand Forks, N.D., and Thelma and the late Keith Hartje of St. Thomas, N.D.

Miss Rowe is an Alpha Omega 2010 graduate of St Andrews Episcopal School. She attended the University of British Columbia in Vancouver, for her freshman year before transferring to the University of Mississippi. She was graduated from Ole Miss in 2014 with a bachelors degree in chemistry. At Ole Miss she was a member of the Delta Delta Delta sorority. She attends Colorado State University in Ft. Collins, and is pursuing her doctorate in biochemistry.

Hartje is a 2011 graduate of the University of California, Davis. He was graduated with a bachelors degree in biochemistry. He has also earned his masters of biochemistry and is on track to receive his doctorate in biochemistry at Colorado State University, Ft Collins, in May.

The couples wedding party will include Elly Jackson of Charlottesville, Va. Christina Holy McRae of Jackson, Maggie Olander of Dallas, and Maggie Hartje of Sacramento. Groomsmen are Nick Gregoire of Loveland, Colo., Kaleb Hartje of Minneapolis, and Kevin and Dylan Lindsey of Santa Maria, Calif.

The couple will exchange vows September 18, at Marys Lake Lodge in Estes Park Colo., with a reception following at the lodge.

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Miss Rowe, Hartje planning September 18 wedding in Colorado - Northside Sun

AMAZONIA, Mo. Texans Lorin and Chris Matthews traveled from the Brazos River to a gravel road splitting corn and soybean fields adjacent to the Missouri River to lay eyes on the moon eclipsing the sun.

The roadside crew included their four children Allyriane and Sterling, 12; Zayn, 10; and Lachlan, 8 as well as Lorins sister, Liskin Kruse, and Kruses daughter, Meredith. The contingent tried out an array of flimsy disposable protective glasses Monday as the moon started nibbling away.

Its very bright, yellow and glowing, Zayn said in describing the cosmic spectacle.

What do you expect? said Sterling, with attitude blending solar analysis and sibling sarcasm. Its the sun.

Lorin Matthews, a physics professor at Baylor University in Waco, and Liskin Kruse, a biochemistry professor at the University of Kansas Medical Center, were drawn to Amazonia, purported population 318, for the sake of family and science. Kruse confessed to being a space wanna-be, while Matthews was bedazzled by the ability of researchers to predict the path of an eclipse with sufficient clarity to let everyone take part.

Its amazing we can predict with such accuracy the location of the sun, the earth and the moon, she said.

If only Mother Natures calibration of thick clouds and rainfall could be anticipated with surgical precision. About the same time the moon was to block out 99 percent of the sun, gray clouds descended on the hamlet of Amazonia and began spitting rain.

Among the dozen or so people parked in this speck of the eclipses hot zone, a few were lucky enough to catch a break in the clouds for split-second glimpses of the most poignant moments of totality, when only the corona of light around the sun can be visible. In this darkness, celebrants in the neighborhood shot off fireworks and firearms.

Allen and Valerie Cassavaugh, of Hopkins, Mo., were two of the visitors in Amazonia to witness the day dying and being reborn after a couple of minutes.

They plunked down lawn chairs next to their vehicle and worked on ham-and-cheese sandwiches and potato chips until the action started in a flat landscape with few trees on outskirts of St. Joseph, Mo.

The sky darkened as promised at totality, and the bizarre colors of sunset could be witnessed in several directions. Still, those clouds wouldnt cooperate.

It was worth the risk, Valerie said, since the next eclipse wont throw this much shade on the central United States until 2024.

Were 60 years old, Allen Cassavaugh said. Were not sure if well be around for the next one.

Originally posted here:
Clouds, rain can't wash fascination with solar eclipse from eyes in Missouri - Topeka Capital Journal