Category Archives: Biochemistry

Biochemistry

Researchers develop a drug effective in a rar – EurekAlert

BEER-SHEVA, Israel, March 21, 2023 Statins are the most commonly used medication in lowering blood cholesterol, prescribed to tens of millions in the Western world. Statins act through inhibition of the enzyme HMG CoA reductase. Nearly 20% of statin users develop muscle symptoms (statin myopathy) including weakness and pain. In about 1%, this myopathy is severe and does not subside months after cessation of statin treatment.

A research team from Ben-Gurion University of the Negev and Soroka Medical Center discovered a severe hereditary muscle disease that develops around the age of 40 years, progressing by the early 50s to complete immobility of the limbs and the chest muscles, necessitating full-time artificial ventilation and eventually culminating in death. They went on to demonstrate that the disease is caused by a mutation in the gene encoding HMG CoA reductase, inhibiting the enzymes activity.

Attempting to cure the severe hereditary disease, the research group synthesized and purified Methylmevalonolactone, the normal product of HMG CoA reductase, which is lacking in those patients. Following testing for safety in mice, the team got an exceptional compassionate use permit to give the novel medication, never given to humans before, to the most severely affected patient, who was near death - completely immobile and fully dependent on artificial ventilation. The patient has now been treated with the medication (orally, 3 times a week) for more than a year, with no side effects.

Not only did she stop deteriorating, she has improved dramatically: she can breathe without support for hours at a time, move her arms and legs extensively and even feed her grandchild. Other patients, some of whom are already in late stages of the disease, are awaiting treatment. The researchers estimate that there are dozens to hundreds of people affected by this hereditary disease that could benefit from this effective life-saving treatment.

Based on the successful treatment of the hereditary disease, the research group went on to test whether the medication can be effective in the treatment of the non-remitting muscle problems occurring in ~1% of statin users. Indeed, they showed that the medication was extremely effective in a mouse model system mimicking the human statin myopathy. This is the first study to link muscle pain and weakness to statin use.

The entire research from the human genetics and biochemistry studies to generation and purification of the medication, to the human and mouse trials were done as part of the PhD thesis of Dr. Yuval Yogev, guided by Prof. Ohad Birk, head of the Morris Kahn Laboratory of Human Genetics at Ben-Gurion University and director of the clinical genetics institute at Soroka Medical Center. Prof. Birk is also a member of the National Institute for Biotechnology in the Negev (NIBN).

The study, published last monthin the Proceedings of the National Academy of Sciences (PNAS), was supported by the Israel Science Foundation.

Based on the findings, the research team are now seeking financial support / collaboration with the pharmaceutical industry to push forward standardized production and licensing of the medication, to save the lives of many individuals worldwide suffering from this hereditary disorder, as well as enabling treatment of tens of thousands of statin-myopathy patients. It should be noted that the FDA procedures are more lenient in licensing medications for rare diseases, thus rapid progress is expected in this regard.

Proceedings of the National Academy of Sciences

Experimental study

People

Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone

6-Feb-2023

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

See the rest here:
Researchers develop a drug effective in a rar - EurekAlert

Biochemistry

Co-infection with superbug bacteria increases SARS-CoV-2 replication up to 15 times – Newswise

Newswise Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2. Researchers at Western have found if you add a superbug methicillin-resistant Staphylococcus aureus (MRSA) into the mix, the COVID-19 outcome could be even more deadly.

The mystery of how and why these two pathogens, when combined, contribute to the severity of the disease remains unsolved. However, a team of Western researchers has made significant progress toward solving this whodunit.

New research byMariya Goncheva,Richard M. Gibson, Ainslie C. Shouldice,Jimmy D. DikeakosandDavid E. Heinrichs, has revealed that IsdA, a protein found in all strains of Staph A., enhanced SARS-CoV-2 replication by 10- to 15-fold. The findings of this study are significant and could help inform the development of new therapeutic approaches for COVID-19 patients with bacterial co-infections.

Interestingly, the study, which was recently published iniScience, also showed that SARS-CoV-2 did not affect the bacterias growth. This was contrary to what the researchers had initially expected.

We started with an assumption that SARS-CoV-2 and hospitalization due to COVID-19 possibly caused patients to be more susceptible to bacterial infections which eventually resulted in worse outcomes, said Goncheva, who is a former postdoctoral associate, previously with the department of microbiology and immunology at Schulich School of Medicine & Dentistry.

Goncheva said bacterial infections are most commonly acquired in hospital settings and hospitalization increases the risk of co-infection. Bacterial infections are one of the most significant complications of respiratory viral infections such as COVID-19 and Influenza A. Despite the use of antibiotics, 25 per cent of patients co-infected with SARS-CoV-2 and bacteria, die as a result. This is especially true for patients who are hospitalized, and even more so for those in intensive care units. We were interested in finding why this happens, said Goncheva, lead investigator of the study.

Goncheva, currently Canada Research Chair in virology and professor of biochemistry and microbiology at the University of Victoria, studied the pathogenesis of multi-drug resistant bacteria (such as MRSA) supervised by Heinrichs, professor of microbiology and immunology at Schulich Medicine & Dentistry.

When the COVID-19 pandemic hit, she pivoted to study interactions between MRSA and SARS-CoV-2.

For this study, conducted at Westerns level 3 biocontainment lab, Imaging Pathogens for Knowledge Translation (ImPaKT), Gonchevas work created an out-of-organism laboratory model to study the interactions between SARS-CoV-2 and MRSA, a difficult-to-treat multi-drug resistant bacteria.

At the beginning of the pandemic, the then newly opened ImPaKT facility made it possible for us to study the interactions between live SARS-CoV-2 virus and MRSA. We were able to get these insights into molecular-level interactions due to the technology at ImPaKT, said Heinrichs, whose lab focuses on MRSA and finding drugs to treat MRSA infections. The next step would be to replicate this study in relevant animal models.

Read the full text of the studyhere.

Originally posted here:
Co-infection with superbug bacteria increases SARS-CoV-2 replication up to 15 times - Newswise

Biochemistry

CD Formulation Provides Pharmaceutical Testing on Tablet Fragility … – Digital Journal

PRESS RELEASE

Published March 22, 2023

New York, USA - March 22, 2023 - Pharmaceutical testing is a must to ensure that all medications meet the top quality, safety, and performance requirements before they enter the market. CD Formulation's cGMP-compliant laboratory is well-equipped to identify both the chemical and structural composition of each drug substance. More recently, the company announced to broaden its service range to tablet fragility test, dissolution test, and disintegration test.

"Staffed with a group of pharmaceutical experts specialized in chemistry, biochemistry, and engineering, CD Formulation has grown to be one of the finest contract service organizations. Our testing laboratories have both expertise and experience to handle the most complex formulation problems," said the Marketing Chief of CD Formulation. "Our analysis and testing services will support pharmaceutical companies at every step and phase of the drug development lifecycle, making sure the entire drug development process complies with the latest regulatory standards and requirements."

Below are some of the testing services newly introduced by CD Formulation:

Tablet Fragility Test

The tablet fragility test is purposed to determine the resistance of tablets against mechanical stress, both shaking and erosion. Theoretically speaking, the higher the percentage of fragility, the greater the loss of tablet life. The physical and chemical properties and stability of API have a great influence on the friability of tablets. Other factors such as excipients and the production process will influence tablet fragility as well. CD Formulation's experienced analysis experts can perform tablet fragility tests by pharmacopeia methods, helping clients to conduct an appropriate risk assessment of the finished drug.

Dissolution Test

Drug dissolution test is a standardized method for measuring the release rate of a drug from a given dosage form, which helps to evaluate the performance of a drug. CD Formulation's dissolution testing is performed under specified conditions according to specific applicable pharmacopoeial standards, such as Four Dissolution Apparatuses Standardized, USP Dissolution Apparatus 1 - Basket (37 C 0.5C), USP Dissolution Apparatus 2 - Paddle (37C 0.5C), USP Dissolution Apparatus 3 - Reciprocating Cylinder (37 C 0.5C), and USP Dissolution Apparatus 4 - Flow-Through Cell (37 C 0.5C).

Disintegration Test

The disintegration test is to evaluate the ability of a sample, mostly tablets, capsules, and enteric-coated tablets, to break into smaller particles under standard conditions. The results will provide critical safety data on the bioavailability of drugs in vivo without the use of in vivo methods. At CD Formulation, a series of methods such as the test-tube method, sieve method with shaker, sieve method, and pharmacopoeial method are used to test disintegration for drugs.

Please visit the website https://www.formulationbio.com/analytical.html to learn more.

About

Successfully solving drug formulation and delivery issues for its global customers is always the goal of CD Formulation. Equipped with advanced facilities that comply with GMP regulations, CD Formulation is of great help to pharmaceutical companies during the progress of formulation, from initial pre-formulation trials to commercial manufacturing. Moreover, after years of untiring efforts, the company has also extended its product lines to pharmaceutical excipients, cosmetic ingredients, food ingredients, offering almost 1,000 excipients or raw materials across the globe.

Media ContactCompany Name: CD FormulationContact Person: Helen SmithEmail: Send EmailPhone: 1-631-372-1052Country: United StatesWebsite: https://www.formulationbio.com

Read more:
CD Formulation Provides Pharmaceutical Testing on Tablet Fragility ... - Digital Journal

Biochemistry

UTEP Joins Project to 3D Print Batteries from Lunar and Martian Soil – The University of Texas at El Paso

EL PASO, Texas (March 22, 2023) The University of Texas at El Paso has joined a project led by NASA to leverage 3D-printing processes with the aim of manufacturing rechargeable batteries using lunar and Martian regolith, which is the top layer of materials that covers the surface of the moon and Mars.

UTEP has joined a project led by NASA to leverage 3D-printing processes with the aim of manufacturing rechargeable batteries using lunar and Martian regolith, which is the top layer of materials that covers the surface of the moon and Mars. Photo by JR Hernandez / UTEP Marketing and Communications

UTEP is a national leader in additive manufacturing for space applications, said Kenith Meissner, Ph.D., dean of the UTEP College of Engineering. I congratulate the team of UTEP researchers involved in this important work. I am confident their work will add significant value to this project, getting us closer to a return to the moon and our first forays beyond.

UTEPs $615,000 grant is part of a $2.5 million project that includes Youngstown State University (YSU), 3D printer manufacturer Formlabs, as well as ICON, the private sector company currently leading the NASA Mars Dune Alpha project aiming to 3D print future habitats on Mars.

The long-term goal of the project is to maximize the sustainability of astronauts' future lunar and Martian missions by reducing payload weight and dead volume. The utilization of local resources widely available on the moon or Mars is crucial to develop infrastructure such as habitation modules, power generation and energy storage facilities.

UTEP is a seminal partner in this NASA-led project with our long and deep heritage in additive manufacturing, said Eric MacDonald, Ph.D., professor of aerospace and mechanical engineering and associate dean in the UTEP College of Engineering. UTEPs reputation in 3D printing, material science and our state-of-the-art facilities were important factors in convincing our NASA partners to pursue this potentially transformative research for space exploration but for terrestrial applications of batteries as well.

ACS Energy Letters, a peer-reviewed journal from the American Chemical Society, published an article titled What Would Battery Manufacturing on the Moon and Mars Look Like? in January, detailing the progress UTEP and NASA researchers have already made on this project.

The published work highlights two types of 3D-printing processes material extrusion (ME) and vat photopolymerization (VPP) to produce shape-conformable batteries on the moon and Mars.

Shape-conformable batteries are complex 3D battery designs that outperform existing commercial batteries because of their ability to fill the dimensions of objects. Such tailored batteries are especially well-suited for applications in small spacecraft, portable power devices, robots, and large-scale power systems for moon and Mars habitat missions.

Another potential outcome of this work is the development of shape-conformable batteries that can be used on Earth. These batteries could be embedded in 3D-printed concrete walls and connected to solar power generation to create compact, self-sustaining homes for disaster response and in developing countries.

While commercial lithium-ion batteries can be found in most of todays applications, manufacturing lithium-ion batteries from lunar and Martian soil is not a viable option since lithium is scarcely available on the moon. For this project, the UTEP research team is currently focusing their work on sodium-ion battery chemistry, based on the greater abundance of sodium.

This project with NASA is an opportunity to demonstrate UTEPs expertise in both energy storage and 3D printing, said Alexis Maurel, Ph.D., French Fulbright Scholar in the UTEP Department of Aerospace and Mechanical Engineering. Additive manufacturing appears as a unique approach to manufacture shape-conformable batteries to support human operations in space and on the surface of the moon or Mars, where cargo resupply is not as readily available.

In addition to MacDonald and Maurel, the UTEP team also includes Ana C. Martinez, Ph.D., postdoctoral researcher in the UTEP Department of Aerospace and Mechanical Engineering, and Sreeprasad Sreenivasan, Ph.D., assistant professor in the Department of Chemistry and Biochemistry.

In the projects initial phase, NASA, UTEP and YSU will identify and work on the extraction of battery materials and precursors from lunar and Martian regolith. The UTEP/YSU team has already developed and VPP 3D printed composite resin feedstocks for each part of the sodium-ion battery (i.e., electrodes, electrolyte, current collector). The team at NASA Marshall Space Flight Center and Ames Research Center developed and ME 3D printed composite inks for the different battery components. UTEP and NASAs Glenn Research Center are then electrochemically testing the completed 3D-printed sodium-ion battery components.

About the University of Texas at El Paso

The University of Texas at El Paso is Americas leading Hispanic-serving university. Located at the westernmost tip of Texas, where three states and two countries converge along the Rio Grande, 84% of our 24,000 students are Hispanic, and half are the first in their families to go to college. UTEP offers 169 bachelors, masters, and doctoral degree programs at the only open-access, top-tier research university in America.

Last Updated on March 22, 2023 at 12:00 AM | Originally published March 22, 2023

By MC Staff UTEP Marketing and Communications

Read more here:
UTEP Joins Project to 3D Print Batteries from Lunar and Martian Soil - The University of Texas at El Paso

Biochemistry

The Protein Society announces its 2023 award – EurekAlert

FOR IMMEDIATE RELEASE

March 22, 2023

THE PROTEIN SOCIETY ANNOUNCES ITS 2023 AWARD RECIPIENTS

LOS ANGELES, CA The Protein Society, the premier international society dedicated to supporting protein research, announces the winners of the 2023 Protein Society Awards, which will be conferred at the 37th Anniversary Symposium, July 13 16, 2023, in Boston, Massachusetts. Plenary talks from select award recipients will take place throughout the 3.5-day event. The scientific accomplishments of the awardees, highlighted here as described by their nominators, demonstrate their lasting impact on protein science.

The Carl Brndn Award, sponsored by Rigaku Corporation, honors an outstanding protein scientist who has also made exceptional contributions in the areas of education and/or service to the field. The 2023 recipient of this award is Professor Arthur Lesk (Penn State University). Dr. Lesk influenced generations of scientists with his analyses of protein structure and evolution, as well as with his textbooks on protein science, genomics, and bioinformatics.

The Christian B. Anfinsen Award, sponsored by The Protein Society, recognizes technological achievement or significant methodological advances in the field of protein science. The 2023 recipient of this award is Professor Mei Hong (MIT). Dr. Hong created innovative tools to interrogate protein structure and dynamics using solid-state NMR spectroscopy.

The Dorothy Crowfoot Hodgkin Award, sponsored by Genentech, is granted in recognition of exceptional contributions in protein science which profoundly influence our understanding of biology. The 2023 recipient is Professor Patricia Clark (University of Notre Dame). Dr. Clark has shed light on mechanisms of co-translational folding, codon usage, and other factors that influence protein structure in vivo.

The new Marie Maynard Daly Award honors its namesake, who was the first Black woman to receive a Ph.D. degree in the United States, conducting pioneering research on chromatin, the ribosome, and cholesterol-hypertension relationships. This award recognizes groundbreaking research at the interface between protein science and human health. The 2023 inaugural recipient is Professor Ren Robinson (Vanderbilt University). Dr. Robinson has pioneered the application and development of mass spectrometry-based proteomics to study aging and neurodegeneration, with a particular focus on health disparities in minority populations.

The Emil Thomas Kaiser Award, sponsored by generous individual contributions, recognizes a recent and highly-significant application of chemistry to the study of proteins. The 2023 recipient is Professor Jason Gestwicki (University of California San Francisco). Dr. Gestwicki has developed innovative tools and approaches to target diseases of protein misfolding.

The Hans Neurath Award, sponsored by the Hans Neurath Foundation, honors individuals who have made a recent contribution of exceptional merit to basic protein research. The 2023 recipient is Professor Elena Conti (Max Planck Institute for Biochemistry). Dr. Conti is recognized for her discovery of mechanisms of RNA export, processing, and quality control in the cell.

The Stein & Moore Award, sponsored by The Protein Society and with support from Wiley, recognizes eminent leaders in protein science who have made sustained high impact research contributions to the field. The 2023 recipient is Professor Kevin Gardner (CUNY Advanced Science Research Center). Dr. Gardner has studied the structure, dynamics, and function of ligand-regulated protein/protein interaction domains from bacteria, plants, and humans to develop innovative optogenetic tools and cancer therapeutics.

The Protein Science Young Investigator Award, sponsored by Wiley, recognizes scientists within their first 8 years of an independent career at the time of nomination who have made an important contribution to the study of proteins. The 2023 recipient is Professor Polly Fordyce (Stanford University). Dr. Fordyce has developed innovative microfluidic systems to study howprotein sequence encodes fuctionat a large scale.

Delegates, exhibitors, sponsors, and the press can learn more about the 37th Anniversary Symposium on The Protein Society website: http://www.proteinsociety.org.

# # #

The Protein Society is the leading international Society devoted to furthering research and development in protein science. Founded in 1986, the purpose of the Society is to provide international forums to facilitate communication, cooperation, and collaboration regarding all aspects of the study of proteins. In support of these goals, the Society publishes Protein Science, the premier journal in the field, hosts an annual international symposium, and facilitates the education of early-career protein scientists across all lines of discipline. The membership of Protein Society represents a wide spectrum of academic, industry, governmental, and non-profit institutions from more than 40 countries around the world. Media inquiries can be directed to Raluca Cadar, Executive Director at 844.377.6834, rcadar@proteinsociety.org.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

Continue reading here:
The Protein Society announces its 2023 award - EurekAlert

Biochemistry

What is Biochemistry? – Definition, History, Examples, Importance …

Have you ever observed how chemical reactions or processes occur within the human body? How do metabolic activities take place? Yes, you will get to know all these life processes through Biochemistry.

The branch of science dealing with the study of all the life processes such as control and coordination within a living organism is called Biochemistry.

This term was introduced to us by Carl Neuberg, the father of biochemistry in the year 1930. This field combines biology as well as chemistry to study the chemical structure of a living organism. The biochemists get into the investigation of the chemical reactions and combinations which are involved in various processes like reproduction, heredity, metabolism, and growth, thus performing research in different kinds of laboratories.

Introduction to Biochemistry includes wide areas of molecular biology as well as cell biology. It is relevant to molecules that make up the structure of organs and cells which is the molecular anatomy. It describes carbon compounds and the reactions they undergo in living organisms. It also describes molecular physiology, which is the functions of molecules in carrying out the requirements of the cells and organs.

It mainly deals with the study of the structure and functions of the biomolecules such as carbohydrates, proteins, acids, and lipids. Hence, it is also called Molecular biology.

The primary branches of biochemistry are listed in this subsection.

It is also referred to as the roots of Biochemistry. It deals with the study of functions of the living systems. This field of biology explains all the interactions between DNA, proteins, and RNA and their synthesis.

Cell biology

Cell Biology deals with the structure and functions of cells in living organisms. It is also called Cytology. Cell biology primarily focuses on the study of cells of the eukaryotic organisms and their signalling pathways, rather than focussing on prokaryotes- the topics that will be covered under microbiology.

Metabolism

Metabolism is one of the most important processes taking place in all living things. It is nothing but the transformations or the series of activities that happens when food is converted into energy in a human body. One example of metabolism is the process of digestion.

Genetics

Genetics is a branch of biochemistry that deals with the study of genes, their variations and the heredity characteristics in living organisms.

The other branches include Animal and Plant Biochemistry, Biotechnology, Molecular Chemistry, Genetic engineering, Endocrinology, Pharmaceuticals, Neurochemistry, Nutrition, Environmental, Photosynthesis, Toxicology, etc.

Biochemistry is essential to understand the following concepts.

To learn more about biochemistry and other important branches of chemistry, such as physical chemistry, register with BYJUS now!

Read more:
What is Biochemistry? - Definition, History, Examples, Importance ...

Biochemistry

What is biochemistry? | New Scientist

Biochemistry is the study of the chemicals that make up life and how they behave. It seeks to explain how inanimate chemicals like carbohydrates and proteins can give rise to living organisms.

Biochemistry as a scientific discipline began in the 1700s and 1800s, with early studies of phenomena like fermentation and the discovery of the first enzyme. However, it blossomed in the 20th century, thanks in part to new techniques like X-ray crystallography that allowed biochemists to study the precise three-dimensional structures of molecules.

Perhaps the most famous biochemical molecule is deoxyribonucleic acid or DNA, the material that carries our genes. The structure of DNA was discovered in 1953 after a frantic (and at times disreputable) race. Famously, DNA is a double helix, made up of two strands that coil around each other. Each strand carries a sequence of letters, which are the basis of genes.

In the wake of this discovery, biochemists like Francis Crick realised that the information on DNA is used to make proteins, which are long chains of smaller molecules called amino acids. Proteins are the workhorses of living cells, doing everything from digesting food to pushing waste out of the cell. The long chains fold up into remarkably intricate structures, which are crucial to the proteins function.

However, before proteins can be made the information from DNA is first copied onto a third kind of molecule called RNA (ribonucleic acid), which is similar to DNA. RNA can also act as an enzyme, as proteins do. Its ability to perform so many tasks has led some biochemists to suggest that it played a key role in the origin of life on Earth, before DNA and protein arose.

Besides genetics, a second key area of biochemistry is metabolism: the processes by which organisms extract energy from their environment (for instance from food) and use it to move and build their bodies. Metabolism involves elaborate sequences of chemical reactions, some of which are cyclic so the original chemicals are recreated at the end. Complex chemicals are broken down into simpler ones to provide energy, and that energy is used to build new chemicals that the organism can use. Different organisms can have radically different metabolisms.

Biochemistry has also revealed that living cells have structural molecules. Some form the walls and membranes that surround cells and hold them together, while others link up into a kind of scaffolding called the cytoskeleton.

Other biochemical molecules are remarkable feats of evolutionary engineering. There are molecular motors and even rotating axles.

Biochemists are still discovering new things about natural organisms (although reports that some organisms can incorporate arsenic into their DNA appear to be false). They have also started designing new biochemistries, for example adding new letters to the DNA alphabet or swapping out some of the amino acids used to make proteins. This synthetic biology may lead to new medicines and other biotechnologies, as well as shedding light on the nature of life.

View post:
What is biochemistry? | New Scientist

Biochemistry

Biochemistry: Definition And Explanation – University of the People

Biochemistry is exciting and fascinating science, and this article will tell you everything youve been wanting to know about the field. Well give you the full biochemistry definition: the basics, the history, as well as the promising degrees and careers you can expect in the biochemists laboratory and beyond.

Biochemistry, or biological chemistry, is the branch of science that studies chemical and physicochemical processes within living organisms.

As a combination of biology and chemistry, biochemistry studies the chemical substances and processes which occur within the biology of the body or any living organisms.

Biochemists study large molecules such as carbohydrates and proteins in relation to metabolism and other important processes within the body. Other molecules that biochemists may study include enzymes and DNA. These types of molecules are important for understanding the complex processes which occur in all living organisms.

The term biochemistry was created by Carl Neuberg, a German chemist, in 1902. But the study itself has been around for over 400 years, essentially since the invention of the microscope in 1665 by Robert Hooke. The microscope made it possible to study cells.

In 1674, Anton van Leeuwenhoek was the first to observe live plant cells under the microscope, which opened up many more possibilities than the dead cells which were being observed up until then. Live cells allowed scientists to observe chemical processes that occurred within and between them.

In the 18th century, a notable discovery in the field was made by the French scientist, Antoine Lavoisier, who proposed the concept of photosynthesis, a process in which plants convert water, sunlight, and carbon dioxide into their nutrients. Lavoisier was also the first person to study cell respiration, which is the process of making the energy molecule in the cells mitochondria.

In the 20th century, DNA was acknowledged as the genetic material which made up the cell. This was established by James Watson and Francis Crick based on the research work of Rosalind Franklin.

Most recently, new technology continues to advance scientific studies in areas such as recombinant DNA, gene splicing, radioisotopic labeling, and electron microscopy.

A career in biochemistry is recommended for those who enjoy research, as it is generally a career in laboratory science. Most careers in the field require at least a bachelors degree, such as a position as a laboratory technician. Other positions, such as laboratory managers or principal investigators of research, will require a masters degree or a Ph.D.

Laboratory technicians engage in bench work and help perform experiments in the lab under the instruction of the principal investigators. Technicians need a bachelors degree in order to be qualified, but more education and research will allow for more independence in the lab.

Lab managers carry more responsibility in the laboratory and may conduct independent research under the guidance of the principal investigator.

Though a masters degree in the field will require an emphasis on research, a Ph.D. prepares biochemists for a career in independent research, principal investigators of research in laboratories, and lecturers in university.

There are also many industry positions available to biochemists. Biochemists may also work in governmental labs or for companies in agriculture, pharmaceuticals, public health, or biotechnology. Some biochemists may also work in services such as toxicology and forensics.

As one may imagine, a contender for biochemistry needs to have a good understanding of both biology and chemistry. Some universities may offer a specific biochemistry track, or students can begin their education by taking a bachelors degree in either biology or chemistry, with a minor in the other.

Biochemists also need to have a good grasp of mathematics and statistics in order to conduct research. As students advance in their studies, they will begin to hone in on their particular interests.

Similar studies include health sciences, which offer courses in biology, anatomy, biostatistics, and disease prevention. Universities such as the University of the People (UoPeople) offer associates and bachelors degrees in health science completely online and tuition-free. The university also offers potential certificate programs in health science that can give ones career the right boost.

As weve seen, the biochemistry definition includes a rich history and an exciting future for further discoveries. Since the invention of the microscope, biochemists have been investigating the complex, hidden world of cells and molecules.

Biochemistry is an exciting and constantly evolving field of science with an emphasis on research and laboratory technology. Different levels of education open up many opportunities for working in the field. If you have a passion for this science, then biochemistry may be a meaningful career choice for you.

More:
Biochemistry: Definition And Explanation - University of the People

Biochemistry

Biochemistry and Molecular Biology – Master of Science – Postgraduate …

Financial aid (need-based funding)

Canadian and US applicants may qualify for governmental loans to finance their studies. Please review eligibility and types of loans.

All students may be able to access private sector or bank loans.

Many foreign governments provide support to their citizens in pursuing education abroad. International applicants should check the various governmental resources in their home country, such as the Department of Education, for available scholarships.

The possibility to pursue work to supplement income may depend on the demands the program has on students. It should be carefully weighed if work leads to prolonged program durations or whether work placements can be meaningfully embedded into a program.

International students enrolled as full-time students with a valid study permit can work on campus for unlimited hours and work off-campus for no more than 20 hours a week.

A good starting point to explore student jobs is the UBC Work Learn program or a Co-Op placement.

Students with taxable income in Canada may be able to claim federal or provincial tax credits.

Canadian residents with RRSP accounts may be able to use the Lifelong Learning Plan (LLP) which allows students to withdraw amounts from their registered retirement savings plan (RRSPs) to finance full-time training or education for themselves or their partner.

Please review Filing taxes in Canada on the student services website for more information.

Applicants have access to the cost calculator to develop a financial plan that takes into account various income sources and expenses.

Follow this link:
Biochemistry and Molecular Biology - Master of Science - Postgraduate ...

Biochemistry

Role of biochemistry to fight malnutrition highlighted – Newspaper – DAWN.COM – DAWN.com

TOBA TEK SINGH: University of Agriculture Faisalabad Vice Chancellor Prof Dr Iqrar Ahmad Khan says nutritional biochemistry is playing a pivotal role in controlling malnutrition which is hitting a large population especially women and children.

He expressed these views during his address as chief guest at the opening session of the one-day symposium on nutritional biochemistry jointly organised by the department of biochemistry and the faculty of food nutrition and home sciences of the university on Monday.

He said development of the agriculture sector was essential to control malnutrition by providing better food for the growing population.

Executive member of Pakistan Science Academy Islamabad Prof Dr Anwarul Hassan Gilani said in this era, nutritional balance could be maintained not only through plants but also through more ingredients in normal diet and adopting healthy lifestyle and dietary habits.

Arid Agricultural University Rawalpindi former VC Dr Khalid Mehmood Khan praised the efforts and achievements of biochemistry worldwide and called it the best solution to overcome malnutrition. Millions of people across the country are suffering from nutritional deficiency due to lack of availability of balanced food. Dean Faculty of Sciences Dr Asghar Bajwa said in the modern era, health problems are worsening due to sedentary lifestyle. We have to eat food keeping nutrition in view for a healthy life.

Chairman department of biochemistry Dr Amir Jamil said the symposium would be able to formulate important recommendations to prevent increase in malnutrition.

Dr Kamran Sharif said the faculty of food nutrition and home sciences is paying full attention to making coordinated efforts with various departments to control malnutrition, which will produce positive results.

Published in Dawn, October 18th, 2022

Here is the original post:
Role of biochemistry to fight malnutrition highlighted - Newspaper - DAWN.COM - DAWN.com