Category Archives: Biochemistry

Assistant to Full Professor job with Department of Biochemistry and Structural Biology | 37289513 – The Chronicle of Higher Education

We are seeking outstanding candidates for Assistant, Associate, or Full Professor positions in Biochemistry and Structural Biology with initial appointment level commensurate with experience and accomplishments (tenure-track or tenured). Candidates may complement existing areas of expertise and/or bring exciting new directions to the BSB department (https://lsom.uthscsa.edu/biochemistry/).

We are interested in exceptional candidates in all areas of biochemistry and structural biology with particular emphasis on nucleic acid, virus, and/or cancer biology. The Department houses University-supported core facilities in macromolecular structure and interactions (X-ray crystallography, Cryo-EM, NMR spectroscopy, SPR, ITC/DSC), mass spectrometry (proteomics and metabolomics), as well as a Center for Innovative Drug Discovery (high throughput screening and medicinal chemistry) (https://wp.uthscsa.edu/biochemistry/core-facilities/).

UT Health San Antonio comprises of Medical, Graduate, Dental, Nursing and Health Profession schools. It is also home to the NCI-designated Mays Cancer Center, the Greehey Childrens Cancer Research Institute, the Sam and Ann Barshop Institute for Longevity and Aging Studies, and the Glenn Biggs Institute for Alzheimers and Neurodegenerative Diseases. San Antonio is the seventh largest city in the U.S., with a historical downtown, a vibrant economy, affordable housing, and many recreational opportunities.

Applicants must have strong research and publication portfolios and compelling plans for future work supported in part by extramural funding. Each position offers a generous startup package, a supportive scientific environment, and the potential for additional recruitment funds from the UT STARs Program and the Cancer Prevention and Research Institute of Texas (CPRIT). Successful applicants will be able to develop a competitive research program, form extensive internal and external collaborations, serve as mentors for students and research fellows, and contribute to teaching in graduate and professional programs. UTHSA is committed to a culturally and gender diverse faculty and is a designated Hispanic Serving Institution.

Interested candidates should visit https://uthscsa.referrals.selectminds.com/faculty and enter job number 2100-0985 in the keyword search to apply. Please upload a cover letter, a curriculum vitae, and a two-page description of current and future research interests before August 15th. The search committee will review applications in late August and begin interviews in September. For questions regarding these opportunities, please email: BSB-Search@uthscsa.edu

UT Health San Antonio is an Equal Employment Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities. All faculty appointments are designated as security sensitive positions.

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Assistant to Full Professor job with Department of Biochemistry and Structural Biology | 37289513 - The Chronicle of Higher Education

Leap of faith: The people who left science to answer a call from God – ABC News

"Science and religion are incompatible," argues biologist, Jerry A. Coyne, in his 2015 book, Faith Versus Fact.

"They have different methods for getting knowledge about reality, have different ways of assessing the reliability of that knowledge, and, in the end, arrive at conflicting conclusions about the universe."

Coyne believes science and religion are diametrically opposed, locked in an irreconcilable "war between rationality and superstition".

For others, however, science and faith go hand in hand.

Some have even left a career in science to answer a call from God.

Benji Callen, Minister at Burnside City Uniting Church in Adelaide, always wanted to be a scientist a geneticist, like his dad.

"Where some people imagined a trophy for a footy premiership, I would imagine a Nobel Prize sitting on my bookshelf," he says.

"I always loved the scientific world. I loved imagining that I could understand something about the universe that no one else had understood before."

Reverend Callen studied science at the University of Adelaide before completing honours in biochemistry. He then spent five years working on a PhD in molecular biosciences.

He was working in a nanotechnology lab at the University of Liverpool in the UK when he received news that his PhD had been accepted.

His five years of hard work had paid off he'd done well and "got a good paper".

His wife, dad, and colleagues at the lab were all elated on his behalf.

But, despite his success, Reverend Callen's heart was elsewhere.

He realised it wasn't his burgeoning science career that most animated him.

Instead, his mind was drawn to his recent discussion with two other members of his church youth group about the meaning of life.

"I thought, 'My science career is going really well why am I far more excited about this conversation?'"

Reverend Callen had started attending church in his late teens and worked in youth ministry at his church in Australia. In Liverpool, he'd joined a Methodist church whose minister also had a PhD biochemistry. "The minister before him had a PhD in astrophysics," the reverend notes.

One of Reverend Callen's lab colleagues also volunteered at a church youth group. "He was happy being a science educator and doing ministry on the side. It was good to know that was possible."

But Reverend Callen realised he was different. While he "enjoyed the intellectual rigour and creativity" of working in science, he "always had this sense that something wasn't quite right".

So, when he and his pregnant wife returned to Australia, he applied for a role as youth pastor at his old church.

He got the job and started studying for a Bachelor of Theology in 2005.

The unease he had felt throughout his lab career vanished.

"I did feel a little sense of sadness or loss," he acknowledges.

"As soon as you step out of science, particularly research science it's really hard to get back into the game. I knew that there was no turning back."

Reverend Callen is now the minister at Adelaide's Burnside City Church, after spending eight years as a minister in the fishing town of Port Lincoln.

"People talk about it being one of the hardest jobs around, and I'd agree with that," he says. "I enjoy the huge variety no one day is ever the same."

Ann Edwards, Priest-in-Charge at St Mark's Anglican Church at The Gap, remembers always having a sense of faith.

As a child, her grandmother would take her to church.

In the days before women's ordination, she used to joke she would become the first female priest in the Anglican church.

"That idea was always there," she says. "I had a sense of vocation and call even from my early teens."

When a wristinjury prevented Reverend Edwards from pursuing the clarinet after school, she chose a new career path almost at random: speech pathology.

"I fell in love with the science of it," she says. "I loved anatomy and physiology and the psychology of it how brains worked. It captivated me."

Reverend Edwards established a rewarding career working with people with swallowing disorders caused by stroke and neurological disease.

"I had no plans to go anywhere," she says.

Despite the satisfaction she derived from speech pathology, Reverend Edwards still felt a call to God.

"I had this real sense of pull into ordained ministry," she says.

In 2014, she followed the call and began training as a priest.

She felt the skillsets she developed in her life as a speech pathologist, manager and researcher would be of great use in the practical business of running a church, particularly in improving disability inclusion, an issue she was passionate about and the focus of her theology thesis.

At the same time Reverend Edwards was embarking on her theology studies, she took up an academic role in speech pathology at the Australian Catholic University. She now wore "two hats" one "as a researcher in speech pathology, and as a researcher in church access."

As a minister, Reverend Edwards finds the same satisfaction from building relationships that she did in her clinical work.

"All those things that I loved about speech pathology are still here I'm still seeing people succeed, I'm still mentoring people," she says.

Reverend Edwards believes her scientific training is good preparation for the challenge of adapting ministry to a digital world, a prospect she finds exciting rather than daunting.

She sees no conflict between her "absolute belief [in] and love of science" and her faith. "My faith is informed by science," she says.

At Christmas, she delivered a sermon on the religious and scientific conceptions of creation and "how beautifully the two work together it's almost like a tapestry".

"The [Bible] stories have so much depth," she says. "They still speak truth if we don't hold them literally, and we hold them as they were meant to be."

She doesn't feel that her scientific background makes her an outlier in the religious world she now occupies.

"If you look at my community it's full of doctors and nurses and social workers," she says.

"There are more PhDs than you can poke a stick at here I'm not unusual at all."

Like Reverend Edwards, Reverend Callen sees science and faith as "complementary" not contradictory.

"Science does a great job of the 'how' of life, answering those 'how' questions 'How do cells work? How do stars work? How does gravity work?' but it does a pretty rubbish job at the 'why' questions 'Why are we here? Why do we have hope? Why do we love? Why do we hate?'"

He believes Christianity offers answers to those philosophical 'why' questions.

Both ministers talk about the "awe and wonder" they find in equal measure in faith and science.

Reverend Edwards finds affirmation of her faith in the natural world. Observing a "tawny frogmouth standing so still that you couldn't even see it in the tree that was a thing of awe and wonder for me," she says.

Reverend Callen says, "To be a good scientist, you need to have a sense of awe and wonder and curiosity about the universe."

He believes worship requires the same qualities. "For me, going into the lab and discovering something new about the universe was my meditation and prayer. It was my awe and wonder."

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Leap of faith: The people who left science to answer a call from God - ABC News

Biological Optical Microscopy Platform Manager job with UNIVERSITY OF MELBOURNE | 302639 – Times Higher Education

Location:ParkvilleRole type:Full time / Fixed-termfor 3 years (with the possibility of extension)Faculty: Faculty of Medicine, Dentistry and Health SciencesDepartment/School:Department of Biochemistry and Molecular BiologySalary: Level B($110,236 - $130,900) or Level C ($135,032 - $155,698) p.a. plus 17% super

The University of Melbourne would like to acknowledge and pay respect to the Traditional Owners of the lands upon which our campuses are situated, the Wurundjeri and Boon Wurrung Peoples, the Yorta Yorta Nation, the Dja Dja Wurrung People. We acknowledge that the land on which we meet and learn was the place of age-old ceremonies, of celebration, initiation and renewal, and that the local Aboriginal Peoples have had and continue to have a unique role in the life of these lands.

About the Department of Biochemistry and Molecular Biology

The Department of Biochemistry and Molecular Biology is a research and research-lead teaching department of the School of Biomedical Science in the Faculty of Medicine, Dentistry and Health Sciences. The Departments research laboratories are mainly located in the Bio21 Molecular Science and Biotechnology Institute (Bio21 Institute) which is adjacent to the University of Melbourne campus at Parkville and the University of Melbourne, Medical Building. We use our strengths in research to create high-quality courses for our undergraduate and graduate students in biomedicine, science and medicine.

https://biomedicalsciences.unimelb.edu.au/departments/biochemistry

About the Role

This is an academic position with major responsibility for management and ongoing development of the Biological Optical Microscopy Platform (BOMP), which makes state-of-the art fluorescence microscopy equipment available to the staff and students of the University of Melbourne, as well as the wider community. You will be actively involved in oversight of the maintenance of a suite of instrumentation, as well as training and research projects.

You will provide leadership and direction to all users of the BOMP facilities in a collaborative research and teaching environment and will manage a team of application specialists.

Other responsibilities include:

The Department and the Bio21 Institute provides superb training facilities and environment for students, as well as outstanding career opportunities for staff.

Biological Optical Microscopy Platform (unimelb.edu.au)

About You

You are a collaborative researcher, with excellent time management and the flexibility to manage and respond to changing priorities and deadlines. You can demonstrate your high level problem-solving and well as your effective verbal and written communication skills. Your ability to foster relationships will set you up for success in this role.

You will also have:

To ensure the University continues to provide a safe environment for everyone, this position requires the incumbent to hold a current and valid Working with Children Check.

About the University

The University of Melbourne is consistently ranked amongst the leading universities in the world. We are proud of our people, our commitment to research and teaching excellence, and our global engagement.

Benefits of Working with Us

In addition to having the opportunity to grow and be challenged, and to be part of a vibrant campus life, our people enjoy a range of rewarding benefits:

To find out more, visithttps://about.unimelb.edu.au/careers/staff-benefits.

Be Yourself

We value the unique backgrounds, experiences and contributions that each person brings to our community and encourage and celebrate diversity. First Nations people, those identifying as LGBTQIA+, females, people of all ages, with disabilities and culturally and linguistically diverse people are encouraged to apply. Our aim is to create a workforce that reflects the community in which we live.

Join Us!

If you feel this role is right for you, please submit your application including a brief cover letter, your resume and your responses against the selection criteria^ (found in the Position Description) for the role.

^For information to help you with compiling short statements to answer the selection criteria and competencies, please go tohttp://about.unimelb.edu.au/careers/selection-criteria

We are dedicated to ensuring barrier free and inclusive practices to recruit the most talented candidates. If you require any reasonable adjustments with the recruitment process, please contact us athr-talent@unimelb.edu.au.

The University of Melbourne is required to comply with applicable health guidance and directions issued from the Victorian Health Minister. All University of Melbourne employees are to be fully vaccinated against COVID-19, unless an exemption order applies. Applicants must meet this requirement when submitting an application.

Position description:PD_BOMP Platform Manager.pdf

Applications close: 24 AUGUST2022 11:55 PMAUS Eastern Standard Time

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Biological Optical Microscopy Platform Manager job with UNIVERSITY OF MELBOURNE | 302639 - Times Higher Education

Researchers Working To Find New Effective Treatments For Tuberculosis – Gilmore Health News

Treatment of Mycobacterium tuberculosis infections is difficult, especially with the emergence of strains that are drug-resistant. Researchers led by University of Oklahoma professor Helen Zgurskaya are now working to find new, more effective drugs for tuberculosis.

Tuberculosis

Read Also: SMARt751 Brings a Solution to Drug Resistance by Tuberculosis Bacteria in Animal Models

Mycobacterium tuberculosis is a pathogenic bacterium that is implicated in the incidence of tuberculosis. Experts say it is the number one cause of infectious disease globally. It affects billions of people worldwide about 25 percent of the worlds population.

Treatment of patients with active symptoms typically involves the use of multiple antibiotics for months. But, as with an increasing number of other bacterial infections these days, this infectious disease is becoming more drug-resistant.

Currently, the treatment requires a combination of antibiotics taken by patients for six months, but now imagine that the disease does not respond to the treatment, stated Zgurskaya, who is the studys corresponding author and a George Lynn Cross Research Professor in the Department of Chemistry and Biochemistry in the Dodge Family College of Arts and Sciences.

We are out of therapeutic options for this infection, and we need new drugs. The paper we published is focused on understanding how recently discovered new inhibitors kill the pathogen, she added.

Read Also: Antibiotics: Two Antibacterial Compounds Effective Against Resistant Tuberculosis Discovered

The new paper appeared in Proceedings of the National Academy of Sciences. Aside from OU scientists, its authors included researchers from Colorado State University, Creighton University, and the Georgia Institute of Technology.

In this study, researchers investigated the mycobacterial membrane protein Large 3 (MmpL3) transporter and its analogs. This inner membrane protein is very critical for coming up with new drugs for tuberculosis.

MmpL3 transporters are vital for shuttling materials that are needed to build the outer membrane of Mycobacterium tuberculosis. They are, thus, essential for bacteria growth and building antibiotic resistance.

Zgurskaya and her colleague isolated MmpL3 from bacterial cells and purified it. Next, they reconstituted this major target for anti-tuberculosis discovery and its analogs in artificial membranes.

The team went further to make a range of substrate mimics and transporter-specific inhibitors. It also examined the activities and properties of these molecules.

Findings showed that all reconstituted proteins aided proton transfer across membranes. However, striking differences were observed in the responses of MmpL3 analogs to pH and their interactions with substrate mimics and indole-2-carboxamide inhibitors.

Read Also: The BCG a Tuberculosis Vaccine Boosts Immune Cells and Reduces Risk of Other Infections

This new paper suggests that certain inhibitors stop the transport activity of MmpL3, together with its analogs, by blocking proton translocation.

This study creates a potent method for characterizing and making new drugs for tuberculosis.

The research lays the groundwork for working out the mechanism of MmpL3 transporters. It also provides a biochemical basis for grasping the inhibition of these transporters by tiny molecule compounds. This will hopefully prove crucial for developing new effective antibiotics for tuberculosis treatment.

The expected next step following the publication of this paper would be to use the developed methods to study other inhibitors, said Zgurskaya. This will help to know which ones are most effective for possible evaluation in clinical trials.

Read Also: Vitamin D Can Help Treat Multi-Drug Resistant Tuberculosis

Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors

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Researchers Working To Find New Effective Treatments For Tuberculosis - Gilmore Health News

Assistant Professor, Associate Professor, and Professor, Bio Sciences and Technology job with VELLORE INSTITUTE OF TECHNOLOGY | 302478 – Times Higher…

Job Description:

Designations Available:

Assistant Professor, Associate Professor, and Professor

Desired Skillset:

Preferred Qualifications:

Ph.D. in Life Sciences / Biotechnology/Molecular Biology/ Biochemistry/ Chemical Engineering

Areas of Specializations:

Responsibilities:

Academics:

Research Consultancy:

Academic / Administration:

Apart from the above duties, any other relevant work is assigned by the Dean of the respective schools.

Department:School of Bio Sciences & Technology (SBST)Location:Vellore, Tamil Nadu, IndiaPosted On:19-Jul-2022Years Of Exp:0 to 20 Years

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Assistant Professor, Associate Professor, and Professor, Bio Sciences and Technology job with VELLORE INSTITUTE OF TECHNOLOGY | 302478 - Times Higher...

Phage therapeutics can be used to fight multidrug-resistant pathogens – News-Medical.Net

Scientists with the Texas A&M College of Agriculture and Life Sciences were among those providing the biochemical tools needed to help save a man's life through a unique emergency intervention in 2016.

Now those Center for Phage Technology scientists in the Texas A&M Department of Biochemistry and Biophysics, Bryan-College Station, have completed a study about that treatment as well as other opportunities for phage therapy.

Their study, "Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy," was published recently in the scientific journal Nature Communications.

The threat of antimicrobial resistance has become a worldwide concern, with the World Health Organization estimating at least 50 million people per year worldwide could die from it by 2050. Center for Phage Technology scientists believe phage therapeutics can be used to fight these resistant bacterial infections.

The premiere case involved phage center scientists working in collaboration with other scientists and physicians at University of California San Diego, UC San Diego, School of Medicine and the U.S. Navy Medical Research Center Biological Defense Research Directorate. Together, they worked to identify phages and determine a treatment plan for Tom Patterson, a professor of psychiatry at the UC San Diego School of Medicine, who was infected by a deadly pathogen while vacationing in Egypt.

Bacteriophages, or phages, are viruses that can infect and kill bacteria without having a negative effect on human or animal cells. Phages can be used alone or in combination with antibiotics or other drugs to treat bacterial infections.

Bacteriophage therapy is an emerging field that many researchers think could yield novel ways to fight antimicrobial-resistant bacteria. At the center, we are interested in the applications of phage therapeutics to fight multidrug-resistant bacterial infections."

Mei Liu, Ph.D., program director at the Center for Phage Technology and a primary investigator for the study

She said the center's work is aided by the team's deep knowledge of phage biology, particularly in the areas of phage lysis and phage genomics.

In 2015, while on vacation in Egypt during the Thanksgiving holiday, Patterson began to experience severe abdominal pain, nausea and vomiting. Local doctors diagnosed him with pancreatitis and treated him accordingly, but the treatments didn't work and his condition worsened.

He was later transported to Germany, where doctors found fluid around his pancreas and took cultures from the fluid's contents. The cultures showed he had been infected with a multidrug-resistant strain of Acinetobacter baumannii, an often-deadly pathogen found in hospital settings and in the Middle East. The same pathogen was also identified in many injured U.S. military members returning home after serving in that part of the world.

In Germany, Patterson was treated with a combination of antibiotics, and his condition improved to a degree where he could be airlifted to the intensive care unit at Thornton Hospital in the UC San Diego Health academic health system. There, however, the medical team discovered that the bacteria had become resistant to antibiotics.

Tom Patterson, in hospital bed, received phage therapy from Robert "Chip" Schooley, MD, left, of UC San Diego Health. (Courtesy photo used with permission of Dr. Tom Patterson)

A "compassionate use" exemption for phage therapy was requested by Dr. Robert "Chip" Schooley, the UC San Diego physician treating Patterson. He was given rapid approval from the U.S. Food and Drug Administration, FDA, to proceed.

Shortly after the phage treatment began, Patterson awakened from a months-long coma. After a long recovery, his health improved greatly, and he was able to return to life as it was before the infection.

Acinetobacter baumannii is recognized as a significant bacterial pathogen in health care-associated infections. A Centers for Disease Control and Prevention report from 2019 stated that antibiotic-resistant pathogens cause more than 2.8 million infections and more than 35,000 deaths annually in the U.S.

Several characteristics of the pathogen that infected Patterson impacted the treatment regimens and outcomes, said Ry Young, Ph.D., director of the Center for Phage Technology.

Patterson's wife, Steffanie Strathdee, Ph.D., associate dean of global health sciences with UC San Diego School of Medicine and an infectious disease epidemiologist, had contacted Young to seek his help in finding a treatment for her husband once she became aware of Young's extensive work with phages.

Young and his lab team took up the challenge and worked almost nonstop for three months to help find a solution.

Phages are viruses that can infect and kill bacteria without affecting human or animal cells. Phage therapy was used extensively in the early 20th century prior to the use of antibiotics. (Stock illustration)

"Cases of resistant infections are becoming more prevalent and very few new antibiotics are available, so the use of bacteriophages to treat or control multidrug-resistant infections is being reconsidered as an alternative strategy," Young said. "Phage therapy is actually a very old concept, having been used extensively in the early 20th century during the pre-antibiotic era."

Phage treatment also has been successful in several more recent case studies involving multidrug-resistant strains of P. aeruginosa, Staphylococcus aureus and Escherichia coli bacteria.

"Phages had been sidelined as a potential treatment for bacterial infections when antibiotics came into wide use in the U.S.," Liu said. "But in other areas of the world, particularly where antibiotics were not immediately available, researchers and doctors have continued developing and practicing phage therapy. Now we are seeing more instances of how phage therapy can be used when antibiotics alone are not sufficient to treat bacterial infections."

Jason Gill, Ph.D., professor in the Texas A&M Department of Animal Science and associate director of the Center for Phage Technology, said while the Patterson case and similar case studies treating multidrug-resistant bacteria have been encouraging in terms of clinical outcome, a more in-depth examination of the phage-host interaction during treatment and its implications is needed.

"The recent study showed that resistance to the therapeutic phages emerged early, and the acquisition of new mobile elements by the bacteria can occur during treatment," said Gill, a corresponding author of the study. "It is important to have a thorough genomic analysis of phages prior to phage treatment in order to maximize treatment success and minimize both effort and resources. There is also a need for conventional experimental testing for phage host range and growth characteristics."

Gill also noted the use of well-characterized phages in a phage cocktail can avoid redundancy and significantly save time and effort in phage production and purification. Eight of the nine phages used for treatment in the Patterson case turned out to be closely related, and this knowledge could have been used to streamline the process if the investigators had known this when assembling the treatment.

"The Patterson case has done a lot to increase awareness of phage therapy and its effectiveness as an alternative therapy for multidrug-resistant pathogenic strains," Liu said. "The success of phage therapy in that case and other cases has brought wider attention to its use and efficacy."

Liu added that the Center for Phage Technology is focusing on developing the technology, standardizing optimal delivery procedures and securing necessary approvals from regulatory agencies to make phage treatment available to patients in the U.S.

"Much of what we did in the Patterson case was unconventional due to the context of phage therapy at that time," Liu said. "But there have been many advances in genomic sequencing and other technologies since then. Today, it would be a much quicker and more efficient process to develop and implement phage therapy if there was another case similar to Patterson's."

Source:

Journal reference:

Liu, M., et al. (2022) Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy. Nature Communications. doi.org/10.1038/s41467-022-31455-5.

Originally posted here:
Phage therapeutics can be used to fight multidrug-resistant pathogens - News-Medical.Net

Postdoctoral Researcher, Seaweed Molecular Biology, Physiology and Genetics, Ryan Institute, School job with NATIONAL UNIVERSITY OF IRELAND, GALWAY |…

Postdoctoral Researcher Seaweed Molecular Biology, Physiology and Genetics, Ryan Institute, School of Natural Sciences.NUIG RES 192-22Applications are invited from suitably qualified candidates for a full time position as a Postdoctoral Researcher (Plant Molecular Biology & Metabolism) in the Plant Systems Biology research group of Dr. Ronan Sulpice at the National University of Ireland, Galway.This 24 months position is funded by the Marine Institute and is available from September 2022 to end date of August 2024.

Job Description:The successful candidate will combine advanced knowledge of molecular genetics research with large-scale metabolic and phenotypic screening of algae. The experiments will consist of large scale metabolic analyses and growth phenotyping screens, whole genome sequencing of Palmaria strains, and data will be aggregated in a built for purpose database. Traits of focus in the project will include identification of genetic markers to identify best performing strains, both for biomass quality and growth performance.Thus experimental approaches employed in the project will include DNAseq, biochemical assays, phenotyping, and extensive field- and lab-level screening.In addition to the experimental aspect of the project, the successful candidate is expected to contribute to the dissemination of the results, help to report the results, and participate in the daily life of the laboratory.

Duties: What the successful candidate will do attached to the specific post (list /bulletpoint)-Sample seaweeds-Extract DNA, and analyse NGS data generated-perform large throughput metabolic and growth analyses-collaborate with the laboratory team technically and scientifically-write papers/reports-interact with stakeholders-participate to report progress to grant agency-participate in dissemination activities-participate in lab management and co-supervision of students-may act as mentor to co-supervisor of students and have limited teaching hours

Qualifications/Skills required:

Essential Requirements:Track record in molecular biology, ideally with a background on micro- or macro-algae.PhD in Plant or seaweed biology and a good research track record that demonstrates strong capabilities and outputs.knowledge of R for analysis of large datasetsStrong proven (via publications, patents and other research outputs) research recordOrganisational, writing and report/paper drafting skills.Driving licenseSkills in biochemistry (metabolic analyses)

Desirable Requirements:Previous experience in a laboratory from the private sectorHave experience in grant writingEvidence for team working (including supervision and/or lab management experience)

Salary: 39,523- 45,609 per annum pro rata for shorter and/or part-time contracts (public sector pay policy rules pertaining to new entrants will apply).Start date: Position is available from 01/09/2022

Continuing Professional Development/Training:Researchers at NUI Galway are encouraged to avail of a range of training and development opportunities designed to support their personal career development plans.

Further information on research and working at NUI Galway is available on Research at NUI Galway

For information on moving to Ireland please see http://www.euraxess.ie

Further information about the laboratory is available at https://sulpice-lab.com/

Informal enquiries concerning the post may be made to Dr. Ronan Sulpice ronan.sulpice@nuigalway.ie

To Apply:Applications to include a covering letter, CV, and the contact details of three referees should be sent, via e-mail (in word or PDF only) to Dr. Ronan Sulpice ronan.sulpice@nuigalway.ie

Please put reference number NUIG RES 192-22 in subject line of e-mail application.

Closing date for receipt of applications is 5.00 pm 15/08/2022

We reserve the right to re-advertise or extend the closing date for this post.

National University of Ireland, Galway is an equal opportunities employer. All positions are recruited in line with Open, Transparent, Merit (OTM) and Competency based recruitment

'NUI Galway provides continuing professional development supports for all researchers seeking to build their own career pathways either within or beyond academia. Researchers are encouraged to engage with our Researcher Development Centre (RDC) upon commencing employment - see http://www.nuigalway.ie/rdc for further information.

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Postdoctoral Researcher, Seaweed Molecular Biology, Physiology and Genetics, Ryan Institute, School job with NATIONAL UNIVERSITY OF IRELAND, GALWAY |...

Seeing the molecular beauty of life – ASBMB Today

When Collins Maina was in secondary school in Kenya, a genetics class piqued his interest in science. He found especially fascinating how certain mutations can be disastrous to the well-being of organisms. And when he took his national exams, he was placed into a biochemistry program, which coincidentally turned out to be a good move for him.

Collins Maina

Collins Maina earned his bachelors degree in biochemistry and molecular biologyfrom South Eastern Kenya University in November.

Maina attended South Eastern Kenya University, where he earned his bachelors degree in biochemistry and molecular biology in November. He said two particularly memorable classes were Biochemistry of Tumors and Biochemical Techniques and Instrumentation.

Not only were these classes interesting, he said, but he also was able to apply what he learned to his own life situation. Learning about the molecular and cellular bases of tumors helped him and his family when his grandfather developed prostate cancer.

I remember I was the go-to guy for the family when they wanted to sort of analyze and translate the pathologists reports, he said.

Learning about laboratory techniques in biochemistry was a highlight for Maina because of the physics involved. He was also able to carry and apply some of this knowledge to his career in industry as a medical representative.

In general, Maina said, biochemistry has helped him better understand what life is and how complex it is at the molecular level.

Its really fun knowing very well that beyond what you see in a person, you see there are a couple of three-letter sequences (codons) that determine who you are, determine the personality, determine so many things in your life how a mishap in the placement of an amino acid, how a molecule that lacks the right conformation can have very detrimental effects on an organism, he said. At the basic level they are nothing more than molecules, very beautiful molecules.

Maina values how relatable biochemistry is to real life. If I dont watch my health currently, Im expecting to develop osteoporosis as I get into my 40s, he said. And so, its like reading the future.

While applying to postgraduate programs and reading extensively about various areas of research, Maina has developed a passion for molecular microbiology and is particularly interested in quorum sensing, which involves responding to cell population density via gene regulation. He plans to continue his studies by earning a Master of Science degree, preferably in Canada, the United States, Scotland or New Zealand. He easily excelled in his undergraduate courses, but the high cost of and limited access to good schools make this goal quite difficult. Few research jobs are available in Kenya. Still, he remains hopeful.

Eventually, Maina said, he sees himself completing a Ph.D. program, doing a lot of research and retiring as a lecturer.

I have so many questions I think I need to answer, he said.

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Seeing the molecular beauty of life - ASBMB Today

Post-Doctoral Associate in the Division of Science, Biochemistry, Dr. Azam Gholami job with NEW YORK UNIVERSITY ABU DHABI | 300813 – Times Higher…

Description

Applications are invited for a fully-funded Post-Doctoral Associate position in the newly established multidisciplinary group of Prof. Azam Gholami at New York University Abu Dhabi. The appointed candidate will be expected to work on:

We seek a highly qualified candidate with a strong background in protein production and purification with a focus on trans-membrane proteins. The appointed candidate will be expected to be familiar with bacterial protein expression and chromatographic purification techniques. Expertise in the reconstitution of membrane proteins into lipid vesicles/polymersomes and skills in microfluidics and optical microscopy are highly advantageous.

Applicants must have a Ph.D. in protein biochemistry or a related field and an excellent track record of original research on the relevant topics. For consideration, applicants need to submit a cover letter, curriculum vitae with full publication list, statement of research accomplishments and interests and contact information for at least three references, all in PDF format. If you have any questions, please email Prof. Azam Gholami atag9141@nyu.edu

This position is not located in the United States and the applicant must be willing to relocate to Abu Dhabi, United Arab Emirates.

The terms of employment are very competitive and include housing and educational subsidies for children. Applications will be accepted immediately and candidates will be considered until the position is filled.

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Post-Doctoral Associate in the Division of Science, Biochemistry, Dr. Azam Gholami job with NEW YORK UNIVERSITY ABU DHABI | 300813 - Times Higher...

10 scientists elected leaders of the ASBMB – EurekAlert

Members of the American Society for Biochemistry and Molecular Biology have elected several new leaders. Three members of the governingCouncilwere re-elected. Theres a new secretary. And both theNominating Committeeand the Publications Committeehave new members.

Council

TheASBMB Councilserves as an advisory board to the president and the executive director for setting priorities and strategic directions, overseeing resource allocations, and ensuring that all activities align with the mission of the society. Councilors are elected for three-year terms and can be re-elected or reappointed to serve one additional term. Three incumbents were re-elected to the Council.

Suzanne Barbourisa professor anddean of the Graduate School at theUniversity of North Carolina at Chapel Hill. She wrote in her candidate statement: During my first term, I have learned more about our society, its challenges and opportunities. I am particularly intrigued by an opportunity that was discussed at a recent Council meeting: pursuing philanthropic support for the ASBMB. My experience as a dean, working with alumni, friends and prospective donors, will be helpful for this effort. Barbour is a former member ofthe Minority Affairs Committee (now the Maximizing Access Committee), has organizedannual meeting symposiaand was honored as a member ofthefirst class of ASBMB fellowsin 2021.Read herfull candidate profile.

Joan Broderickis a professor and department head atMontana State University. In 2022, she becamean elected member of the National Academy of Sciences. Broderick has been at Montana State since 2005; before that she was on the faculty ofa small liberal arts college and a research-intensive state university. This range of experiences has given me a broad perspective on science education and academic research and the intersection of the two, she wrote.Read herfull candidate profile.

Matthew Gentryis a professor at theUniversity of Kentucky. He has served on the societys Membership Committee, Public Affairs Advisory Committee andJournal of Biological Chemistry editorial board. For this term on the Council,he has prioritized sharing with members how to utilize their passions to serve on an ASBMB committee, recruiting the societys next executive director; serving as a resource and adviser to PresidentAnn Stock, who was elected in 2021, and headquarters leaders; and spreading the word about how the ASBMB can help biochemists at all career stages.Read hisfull candidate profile.

Nominating Committee

TheASBMB Nominating Committeenominates regular members of the society to stand for election for president, the Council, the Publications Committee and the Nominating Committee.Committee members are elected for three-year terms and can be re-elected or reappointed to serve one additional term. ASBMB members elected two new committee members this year.

Juan L. Mendozais an assistant professor at theUniversity of Chicago. He twice has co-chaired the Enzyme Interest Group at the ASBMB annual meeting and is an active advocate for diversity and inclusion. I am passionate about making education in STEM accessible to everyone and inspiring future generations of scientists. For me, this includes active participation in community outreach and societies such as the ASBMB, he wrote.Read hisfull candidate profile.

Jeremy Thorneris a distinguished professor emeritus at theUniversity of California, Berkeley. He won the ASBMBsHerb Tabor Research Award in 2019. The many activities of ASBMB are best achieved by ensuring gender equity and diversity in its advisory bodies and leadership, as well as in its general membership, he wrote. To thrive, our organization needs to be inclusive, and to hear from and recruit diverse voices. Hence, the most important function of the Nominating Committee is to make certain we draw on the rich pool of our membership and secure the participation of individuals from all quarters of the biochemical sciences.Read the full candidate profile.

Secretary

The secretary is responsible for reviewing the minutes of the society, serving on the Nominating Committee and the Audit Committee, and completing other duties as assigned by the Council, which may include certifying Council resolutions to support the operations of the society.The secretary is a voting member of Council and participates in the governance of the society. The secretary serves a three-year term.

George Carmanis a distinguished professor atRutgers Universityand director of theRutgers Center for Lipid Research. He won the ASBMBsAvanti Award in Lipids in 2012,has beenan associate editorfor the societys Journal of Lipid Research and Journal of Biological Chemistry, and has served on the Council and several committees. He co-directs the societysLipid Research Division. The ASBMB has been a large part of my professional life since I joined the society in 1980, he wrote. Throughout my career, I have profited from formal and informal mentors, and I am obliged to pay forward my knowledge and experiences to early-career scientists including undergraduate and graduate students, and postdoctoral associates. Carman was a member of the societysinaugural class of fellowsin 2021.Read hisfull candidate profile.

Publications Committee

TheASBMB Publications Committeeoversees the societys scholarly publishing activities, advises the Council on policy and ethical issues that may arise, and advises journal editors about editorial matters, including the approval of associate editor appointments. Committee members are elected for five-year terms and can be re-elected or reappointed to serve one additional term. ASBMB members elected four new committee members.

Walid Houryis a professor at theUniversity of Toronto. Hes been a member of the Journal of Biological Chemistry editorial board since 2017. During his term on the committee, he intends to advocate for innovative article review and publication formats. He wrote: I find this to be especially important given the new and different article reviewing and publishing approaches being used by other journals. Hence, a clear policy needs to be established to address how ASBMB journals will interact with open-access preprint repositories such as bioRxiv and what value will be placed on reviews provided by journal-independent peer-review platforms such as the Review Commons.Read hisfull candidate profile.

Marcelo Kazanietzis a professor at theUniversity of Pennsylvania. He has been an editorial board member for the Journal of Biological Chemistry and several other peer-reviewed publications. I understand emerging challenges to keep disseminating our scientific discoveries in a highly competitive environment.I aim to support efforts toward facilitating communication between editors, authors and readers, with the ultimate goal of promoting high-impact science while affirming strong ethical publishing values, he wrote.Read hisfull candidate profile.

Daniel Leahyis a professor atUniversity of Texas at Austin. He served on the ASBMB Council from 2012 to 2015, has helpedorganize meeting themes and other society events,and is a member of the societys2022 class of fellows. Chief among the jewels in the ASBMB crown are its publications, which are run by scientists for scientists, and I am delighted at the opportunity to help continue the ASBMBs tradition of excellent publications as modes of scientific communication continue to evolve, he wrote.Read hisfull candidate profile.

Anne-Frances Milleris a distinguished professor at theUniversity of Kentucky. She has been a member of the Journal of Biological Chemistry editorial board and a member of the Publications Committee before. I understand that publications are central to both the professional conduct of science and also its social fabric, she wrote. I am a big admirer of how ASBMBs publications have spanned both spheres via the several journals the society produces. ASBMB Today nurtures networks of people and interest and keeps the science fun, engaging us all beyond the boundaries of our own specializations and keeping the best of our humanity connected to the best of our science. Meanwhile, ASBMBs established research journals provide critical channels for sharing high-quality scientific progress, complete with the assurances of expert peer review.Read herfull candidate profile.

About the American Society for Biochemistry and Molecular Biology (ASBMB)

The ASBMB is a nonprofit scientific and educational organization with more than 12,000 members worldwide. Founded in 1906 to advance the science of biochemistry and molecular biology, the society publishes three peer-reviewed journals, advocates for funding of basic research and education, supports science education at all levels, and promotes the diversity of individuals entering the scientific workforce. For more information about the ASBMB, visitwww.asbmb.org.

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10 scientists elected leaders of the ASBMB - EurekAlert