Category Archives: Biochemistry

Biochemistry

Biochemistry – McGill University

Welcome to Biochemistry

How do cells work? How do dysfunctional molecular interactions result in diseases? And how could we design molecules to cure those diseases? Biochemistry is the science that explains life at a molecular level and finds solutions to complex health disorders. Whether you are looking for a career as laboratory scientist, clinical biochemist, forensic scientist, geneticist, precision medicine consultant, medical liaison manager, or if you simply want to become a top notch researcher recognized worldwide, Biochemistry provides the solid core program and opportunities you were looking for.

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Biochemistry - McGill University

Biochemistry

Companion Animal Diagnostics Market: Competitive Landscape Analysis with Forecast by 2027 – BioSpace

Wilmington, Delaware, United States: Companion animals are used for extrovert display, psychological support, and amusement support. Companion animals include dogs and cats. Companion animal diagnostics is an integral part of management as well as prevention of outbreaks of diseases among companion animals.

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Companion animal diagnostics include clinical biochemistry products, immunodiagnostics, hematology, and others. These are used in the treatment of diseases associated with the immunological system, digestive system, reproductive system, respiratory system, and urinary system of companion animals.

Increase in obesity and various diseases in companion animals, globally, has fueled the need for new diagnostic options. In developed countries such as the U.S., governments strongly emphasize on pet insurance. Clinical biochemistry technology is widely utilized in the diagnosis of veterinary diseases with the help of blood and urine analysis. Companion animal diagnostic products are mostly used in clinical pathology due to increasing demand for diagnostic products in pathology labs and rising number of pathology tests performed on pets. In terms of companion animals, dog are a highly popular companion animals. In terms of competition, IDEXX Laboratories, Inc. and Zoetis, Inc. are major manufacturers of companion animal diagnostic products.

Increase in the demand for advanced products for veterinary disease diagnosis boosts the global companion animal diagnostics market.

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Companion Animal Diagnostics Market: Overview

Increase in companion animal ownership is a major trend being witnessed in the animal healthcare market. Spending capacity on companion animals is also on the rise.

According to the National Pet Owners Survey conducted by the American Pet Products Association (APPA) in 2018, around 68% of households in the U.S own a companion animal or pet.

According to a report published by the Federal Trade Commission (FTC), the U.S. government spent around US$ 72.5 Bn on its pet industry in 2018, which includes food, veterinary care, prescription and OTC medications, and other pet services and products.

Pet obesity is a major issue in the U.S. According to a report by the Association for Pet Obesity Prevention (APOP), in 2018, obesity affected around 55.8% of dogs and 59.5% of cats in the U.S.

Increased longevity of companion animals due to improvements in diagnostics, greater emphasis on wellness and prevention by veterinarians as well as owners, and better nutrition have expanded the use of companion animal diagnostics.

Due to all these factors, the global companion animal diagnostics market is set to expand at a high CAGR of ~9%, to be valued at ~US$ 5 Bn by the year 2027.

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Global Companion Animal Diagnostics Market: Key Segments

In terms of technology, clinical biochemistry is the leading segment in the global companion animal diagnostics market. This is due to major focus of manufacturers on launching new diagnostic products such as chemistry analyzers and glucose monitors. Additionally, extensive application of this technology and increase in the preference for point of care glucose monitoring devices is likely to fuel the segment in the global companion animal diagnostics market.

Clinical pathology is projected to be a highly attractive segment in the global companion animal diagnostics market during the forecast period. Clinical pathology is highly preferred for diagnosis over various companion animal diagnoses, and an increase in the prevalence of various chronic diseases associated with companion animals has led to an increase in the number of diagnosis tests. These factors boost the clinical pathology segment in the global companion animal diagnostics market.

Dogs are extremely popular companion animals all around the world as compared to any other animal. Increasing dog population and high incidence rate of obesity in dogs are projected to boost the segment in the global companion animal diagnostics market during the forecast period. Moreover, increasing pet ownership across the globe is also a major factor driving the segment in the overall companion animal diagnostics market.

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Veterinary Reference Laboratories is a highly preferred end user in the global companion animal diagnostics market. Increase in the number of veterinary reference laboratories across the globe and availability of new diagnostic products in veterinary reference laboratories are expected to propel the retail pharmacies segment in the global companion animal diagnostics market.

Global Companion Animal Diagnostics Market: Major Players

Leading players analyzed in the report on the global companion animal diagnostics market include

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Biochemistry Analyzers Market: Widespread advancements in the medical field have primarily been responsible for driving the global biochemistry analyzers market.

Veterinary Biochemistry Analyzers Market: Increasing incidences of disease outbreak in animals and technological advancements are expected to drive the veterinary biochemistry analyzers market.

Companion Diagnostics Market: The global companion diagnostics market is expected to witness tremendous growth opportunities due to rising incidences of oncology and chronic disorders across the globe.

Companion Animal Drugs Market: Rising number of companion pet adoption centers globally where companion animals need to be kept safe is increasing the demand for companion animal drugs to keep them healthy and safe.

Molecular Diagnostics Market: Rise in demand for personalized health care, and surge in awareness about molecular diagnostics are the key factors projected to drive the global molecular diagnostics market during the forecast period.

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Companion Animal Diagnostics Market: Competitive Landscape Analysis with Forecast by 2027 - BioSpace

Biochemistry

ACS announces 2022 awards – ASBMB Today

In late March, the American Chemical Society announced its awards for 2022. Among the honorees were American Society for Biochemistry and Molecular Biology members Karen Allen, Benjamin Cravatt, Kimberly Jackson and Carlito Lebrilla.

Karen Allen

Karen Allen, a professor and chair of the chemistry department at Boston University, won the 2022 Abeles and Jencks Award for the Chemistry of Biological Processes. Allen's lab studies the structure, function and mechanisms of phosphatases, phosphoglycosyltransferases and decarboxylases, working to understand both reaction mechanisms and enzyme evolution. Allen is a co-organizer of the 2023 ASBMB Annual Meeting. She is the inaugural recipient of this award, which was named for the late enzymologists William Jencks and Robert Abeles, who taught and studied mechanistic enzymology at Brandeis University. Given by the ACS division of biological chemistry, the award celebrates "outstanding contributions to the understanding of the chemistry of biological processes."

Benjamin Cravatt

Benjamin Cravatt, a professor of chemistry and chair of chemical biology at Scripps Research, received the Alfred Bader Award for outstanding contributions in bioinorganic or bioorganic chemistry. Cravatt's lab developed a technique to use chemical probes that bind to and tag enzymes active sites, enabling researchers to read out enzyme activity at proteome scale. They have used the technique to study endocannabinoid signaling, cancer and neurological disorders. Researchers in the lab have also extended their methods to globally map small moleculeprotein interactions and discover chemical probes for historically undruggable proteins. Cravatt was also one of three recipients of the 2022 Wolf Prize in Chemistry, and he won the ASBMBMerck Award in 2014. The late Alfred Bader, a Canadian chemist, businessman and philanthropist, and his family established this award in 1986.

Kimberly Jackson

Kimberly Jackson, a professor and chair of the department of chemistry and biochemistry at Spelman College, received the ACS award for Encouraging Disadvantaged Students into Careers in the Chemical Sciences. Jackson is director of the food studies program at Spelman, a historically black college. Her lab studies potential therapeutic molecules for advanced prostate cancer, and many of the undergraduates who have trained with her later earned Ph.D.s or medical degrees. The award includes a prize of $10,000, which Jackson directed to an Atlanta-based nonprofit called PinkSTEM that aims to empower girls to succeed in science, technology, engineering and mathematics.

Carlito Lebrilla

Carlito Lebrilla, a distinguished professor and former chair of the chemistry department at the University of California, Davis, received the Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry. Known for his glycoproteomics work, Lebrilla studies disease biomarkers in cancer and Alzheimers disease, along with bioactive compounds breast milk and how milk glycoproteins affect infant microbiomes. Lebrilla is a member of the editorial advisory board of Molecular & Cellular Proteomics. This ACS award, sponsored by the Waters Corporation, is named for two noted mass spectrometrists; Field worked in developing chemical ionization, and Franklin studied the chemistry of ion molecules.

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ACS announces 2022 awards - ASBMB Today

Biochemistry

Masters in Biochemistry and Molecular Biology | Georgetown University

The Master of Science in Biochemistry & Molecular Biology at Georgetown University is a basic science program that infuses core concepts of biochemistry and molecular biology as applied to biomedical sciences and biotechnology, providing students with a rigorous and challenging curriculum. Graduates from the program excel in various career paths with government agencies, academic institutions, research laboratories, and biotechnology companies. Alumni have also continued their education by pursuing doctoral, medical, and law degrees, using the skills and training at Georgetown University to propel their future academic and research careers.

Core concepts and skills are taught through required core courses, advanced electives, special topics courses, and a 4 credit internship. At least 30 graduate credits with a cumulative GPA of 3.0 or greater are required for the M.S. degree. Our courses expose students to advanced methods in biochemistry, molecular biology, and cell biology, laboratory research, and literature-based research and include a significant number of hands-on lab-based courses that develop research expertise.

Our program offers a well-organized, intensive capstone internship program that culminates in students presenting their research at tri-annual poster presentation sessions. The internships are done with research mentors in various GUMC laboratories on-campus, or off-campus in government agencies such as NIH and FDA or biotechnology companies.

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Masters in Biochemistry and Molecular Biology | Georgetown University

Biochemistry

‘Molecular LEGO’ Study Analyzes Building Blocks of Partially Disordered Protein | Newsroom – University of California, Merced

Bioengineering Professor Victor Muoz and his lab have created a new way to solve some of the mysteries among an increasingly important class of proteins that dont appear to have any specific structures but serve very important functions, including the complex genetic processes that separate high-order organisms from single-cell bacteria.

They call it molecular LEGO, pulling the proteins apart and rebuilding them, segment by segment.

This new method could dramatically affect a relatively young and exploding field within biochemistry and biomolecular sciences for researchers worldwide.

Molecular LEGO is detailed in a new paper entitled A Modular Approach to Map Out the Conformational Landscapes of Unbound Intrinsically Disordered Proteins in the Proceedings of the National Academies of Science, out now.

For the past four decades, biochemists and biomolecular engineers have used techniques such as X-ray crystallography, NMR and cryo-electron microscopy to study proteins that fold into defined structures that dictate how they work like the tiny machines they are.

Scientists have also traditionally used a method to help understand what makes these proteins behave as they do. They create mutations in the protein, changing single amino acids, and studying how much that change affects the proteins structure, stability, and the rates of folding and unfolding.

Its the only experimental technique we have for studying what makes a particular amino acid sequence special to fold into one particular structure and serve one particular function, Muoz said.

Intrinsically disordered proteins (IDPs), discovered in the past 20 years, dont have apparent structures at least none that current techniques can discern. They change shapes based on their environments and conditions and tend to fold into structures when they bind specific partner molecules. They have the unique ability to morph in response to multiple partners and can process sophisticated inputs and outputs.

But its a mystery whether their response is passive entirely determined by the partner or controlled via an internal folding mechanism that has yet to be revealed.

That is the question Muoz and his group are trying to answer as they experiment with and model a partially disordered protein called NCBD to uncover clues as to how it performs its sophisticated biological function. They take this disordered protein and make it even more disordered by breaking NCBD into pieces and studying each one separately.

Thats the most disordered thing you can have because youve removed all the connections, Muoz said. But those are the LEGO building blocks. They give us a reference point.

Then the researchers recombine the segments in order, one at a time, to see how each restored, larger segment behaves.

Is it just the sum of its parts or some cooperation between the connected parts? he said.

Ordered proteins behave as if they have on and off switches, while IDPs seem to work more like rheostats, changing gradually.

It could turn out that IDPs only appear disordered because scientists are looking at them using techniques that dont give them the whole picture. The IDPs must have some structure because they are able to select specific partners, change shape when bound to those partners and complete complicated actions in very specific ways, Muoz explained.

Muoz wrote the paper with graduate students Thinh D.N. Luong, in the Chemistry and Chemical Biology program and Suhani Nagpal, in the Bioengineering program, as well as Mourad Sadqi, a project scientist with the NSF-CREST Center for Cellular and Biomolecular Machines (CCBM), for which Muoz serves as director.

More IDPs are being discovered and are quickly becoming a very important class of proteins. They are more commonly found in high-order organisms, such as humans.

It seems like the paradigm that is emerging is that all these proteins are key in regulation and responsible for all the complexity that is emerging in high-order organisms without having to vastly increase the number of genes, Muoz said.

For example, an E. coli bacterium has about 5,000 genes, while a human has about 30,000.

So, you can see that we definitely have to do something special with those 30,000 genes to make us, compared with a bacterium, a very simple thing, Muoz said. The thought is that this is achieved by sophisticated regulation, networks and other complicated processes, and it seems like the key players in all this are these IDPs. They are often found at the hubs in these networks.

The next steps for this work will be to apply the new technique to other proteins and to recombine the proteins outside the segment order defined by the gene sequence to see how that affects the segments and function.

This connects with a lot of our engineering work in which were trying to build biosensors and new methods for diagnostics, Muoz said. We can use these proteins as the scaffolds to make responsive systems on the molecular level.

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'Molecular LEGO' Study Analyzes Building Blocks of Partially Disordered Protein | Newsroom - University of California, Merced

Biochemistry

Senior Lecturer or Associate Professor in Biochemistry and Pharmacology job with UNIVERSITY OF MELBOURNE | 295930 – Times Higher Education

Location: ParkvilleRole type: Full time /ContinuingFaculty: Faculty of Medicine, Dentistry and Health SciencesDepartment/School:Department of Biochemistry and PharmacologySalary: Level C ($135, 032 - $155,698) OR Level D ($162,590 - $179,123) p.a. plus 17% super

Founded in 1853, the University of Melbourne is Australias #1 university and is consistently ranked amongst the leading universities in the world. We are proud of our people, our commitment to research and teaching excellence, and our global engagement.

About theDepartment of Biochemistry and Pharmacology

The Department of Biochemistry and Pharmacology is committed to developing the careers and wellbeing of our students and staff, fostering a culture that supports us all to do our best work. We are guided by our values in our pursuit of excellence.The Department of Biochemistry and Pharmacology has critical mass, interdisciplinary teaching and a remarkable breadth and depth in research expertise that underpin our key themes of molecular understanding of biology and disease, translational research, drug discovery and development. Our researchers are strongly committed to high-impact discovery research and in translating breakthroughs to societal outcomes when the opportunity arises.

The Department of Biochemistry and Pharmacology is strongly committed to supporting diversity and the representation of women. In line with the special measure H103/2014 provided for under section 12 of the Equal Opportunity Act 2010 (VIC), the Department of Biochemistry and Pharmacology strongly encourages applications from suitably qualified female candidates. We intend that at least one of the two appointees will be a female.

About the Role

We have two positions available as a Senior Lecturer or Associate Professor, who will develop and maintain a high-level research program in a field of pharmacology that is complementary to existing areas of research strength in the Department. You will be encouraged to contribute to interdisciplinary research within the School of Biomedical Science and Faculty of Medicine, Dentistry and Health Sciences and the wider academic community. You will also join a successful team in delivering and supporting teaching and learning in pharmacology and therapeutics within the Department and the broader School of Biomedical Sciences.

In a typical week at work, you may:

About You

You are a confident communicatorwith a demonstratable proactive reflective teaching practice. Your highly-developed interpersonal skills allow you to work collaboratively with internal and external colleagues, and you are passionate about mentoring and guiding junior research staff in their academic trajectory.

Ideally, you will further have:

Benefits of Working with Us

In addition to having the opportunity to grow and be challenged, and to be part of a vibrant campus life, our people enjoy a range of rewarding benefits:

To find out more, please visithttps://about.unimelb.edu.au/careers/staff-benefits.

Be Yourself

At UoM, we value the unique backgrounds, experiences and contributions that each person brings to our community, and we encourage and celebrate diversity. Indigenous Australians, those identifying as LGBTQIA+, females, people of all ages, with disabilities or culturally diverse backgrounds are encouraged to apply for our roles. Our aim is to create a workforce that reflects the community in which we live.

Join Us!

If you feel this role is right for you, please submit your application including a brief cover letter, your resume and your responses against the selection criteria^ (found in the Position Description) for the role.

^For information to help you with compiling short statements to answer the selection criteria and competencies, please go tohttp://about.unimelb.edu.au/careers/selection-criteria

Should you require any reasonable adjustments with the recruitment process, please contact the Talent Acquisition team athr-talent@unimelb.edu.au.

Due to the impacts of COVID-19, we are currently prioritising applications with current valid working rights in Australia and candidates who are not affected by travel restrictions. Please see the latest updates to Australia's immigration and border arrangements: https://covid19.homeaffairs.gov.au/

The University of Melbourne is required to comply with applicable health guidance and directions issued from the Victoria Health Minister. The University of Melbourne requires all University of Melbourne employees to be fully vaccinated against COVID-19, unless an exemption order applies. All applicants therefore must meet this requirement when submitting an application.

Position description:Senior Lecturer, Associate Professor PD.docx

Applications close:30 JUNE 2022 11:55 PMAUS Eastern Standard Time

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Senior Lecturer or Associate Professor in Biochemistry and Pharmacology job with UNIVERSITY OF MELBOURNE | 295930 - Times Higher Education

Biochemistry

Four Faculty Members, Five Alums Elected to National Academy of Sciences – Caltech

Four members of the Caltech faculty have been elected to the National Academy of Sciences (NAS) this year. Election to the academy is considered one of the highest professional honors that can be bestowed upon a scientist.

The faculty members elected to the NAS this year are Bil Clemons, the Arthur and Marian Hanisch Memorial Professor of Biochemistry; Linda Hsieh-Wilson, the Milton and Rosalind Chang Professor of Chemistry; Michael Elowitz, professor of biology and bioengineering and Howard Hughes Medical Institute Investigator; and Nicholas Scoville, the Francis L. Moseley Professor of Astronomy, Emeritus.

Bil Clemons uses the tools of biochemistry to explore the molecular building blocks of life. The structural biologists in the Clemons lab work on problems related to how membrane proteins are made and inserted into cell membranes and the chemistry of enzymes that catalyze the transfer of sugars onto lipids. The work aims toward basic biological understanding that may lead to the development of novel therapeutics. He joined the Caltech faculty in 2005.

Linda Hsieh-Wilson studies the molecular bases of fundamental processes in the brain using organic synthesis, biochemistry, molecular and cellular biology, and neurobiology. Her research aims to better understand how proteins and carbohydrate molecules are involved in the development of neurons and communication between neurons, and how these processes contribute to neuroplasticity and neurological disorders. She joined the Caltech faculty in 2000.

Michael Elowitz works in the fields of synthetic and systems biology. His research aims to enable the programming of new biological functions with molecular circuits of interacting genes and proteins. His lab's main strategy is to design and engineer synthetic circuits that allow cells to process, remember, and communicate information, often in unexpected ways. By designing synthetic circuits, his group is discovering fundamental principles of natural biological circuit design and providing foundations for new kinds of biomedical therapies. He joined the Caltech faculty in 2003.

Nicholas Scoville founded the Cosmic Evolution Survey (COSMOS), which probes the formation and evolution of galaxies as well as black holes, in 2003. He led the survey for its first 10 years. He also served as the director of the Owens Valley Radio Observatory (OVRO) from 1986 to 1996. More recently, he used Atacama Large Millimeter/submillimeter Array (ALMA) in Chile to study the evolution of more than 700 galaxies within the COSMOS survey field. He joined the Caltech faculty in 1984.

Additionally, five Caltech alumni were elected to the academy. They are France Crdova (PhD '79), former president of the National Science Foundation, current president of Science Philanthropy Alliance, member of the Caltech Board of Trustees, and 2007 recipient of Caltech's Distinguished Alumni Award; Lance Dixon (BS '82), professor at the SLAC National Accelerator Laboratory; Leonidas Guibas (BS '71, MS '71), Paul Pigott Professor of Computer Science and Electrical Engineering in the School of Engineering at Stanford University; William Jones (PhD '79), the Charles F. Houghton Professor of Chemistry at the University of Rochester; and Kate Scholberg (MS '91, PhD '97), the Arts & Sciences Distinguished Professor of Physics and Bass Fellow at Duke University.

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Four Faculty Members, Five Alums Elected to National Academy of Sciences - Caltech

Biochemistry

Research Fellow, Cancer Biology and Biochemistry job with UNIVERSITY OF MELBOURNE | 296107 – Times Higher Education

Location: ParkvilleRole type: Full time/Fixed-termfor 12 monthsFaculty: School of Biomedical SciencesDepartment/School: Department of Biochemistry and PharmacologySalary: Level A $77,171 - $104,717 (pro rata for part-time) p.a. plus 17% super

Founded in 1853, the University of Melbourne is Australias #1 university and is consistently ranked amongst the leading universities in the world. We are proud of our people, our commitment to research and teaching excellence, and our global engagement.

About theDepartment of Biochemistry and Pharmacology

The Department of Biochemistry and Pharmacology has critical mass, interdisciplinary teaching and a remarkable breadth and depth in research expertise that underpin our key themes of molecular understanding of biology and disease, translational research, drug discovery and development.

It is envisaged to consolidate the research activities of the new Department. With respect to teaching, the departments offerings are complementary, and we are looking forward to developing new courses across our joint areas of expertise.

About the Role

A highly motivated early career researcher is sought to join the Department of Biochemistry & Pharmacology, Faculty of Medicine, Dentistry & Health Sciences in the University of Melbourne. The successful applicant will drive the in vivo projects taking place in the lab, thus extensive experience with small animal handling and animal models of disease (preferably cancer) is essential.

In a typical week at work, you may:

About You

You are a confident communicator with an ability to be proactive and to use initiative to solve problems quickly and efficiently. Your highly developed organisational skills and record keeping capabilitieswill enable you toprioritise a range of tasks, manage time effectively and meet deadlines in a busy environment.

Ideally, you will further have:

Benefits of Working with Us

In addition to having the opportunity to grow and be challenged, and to be part of a vibrant campus life, our people enjoy a range of rewarding benefits:

To find out more, please visithttps://about.unimelb.edu.au/careers/staff-benefits.

Be Yourself

At UoM, we value the unique backgrounds, experiences and contributions that each person brings to our community, and we encourage and celebrate diversity. Indigenous Australians, those identifying as LGBTQIA+, females, people of all ages, with disabilities or culturally diverse backgrounds are encouraged to apply for our roles. Our aim is to create a workforce that reflects the community in which we live.

Join Us!

If you feel this role is right for you, please submit your application including a brief cover letter, your resume and your responses against the selection criteria^ (found in the Position Description) for the role.

^For information to help you with compiling short statements to answer the selection criteria and competencies, please go tohttp://about.unimelb.edu.au/careers/selection-criteria

Should you require any reasonable adjustments with the recruitment process, please contact the Talent Acquisition team athr-talent@unimelb.edu.au.

Due to the impacts of COVID-19, we are currently prioritising applications with current valid working rights in Australia and candidates who are not affected by travel restrictions. Please see the latest updates to Australia's immigration and border arrangements: https://covid19.homeaffairs.gov.au/

The University of Melbourne is required to comply with applicable health guidance and directions issued from the Victoria Health Minister. The University of Melbourne requires all University of Melbourne employees to be fully vaccinated against COVID-19, unless an exemption order applies. All applicants therefore must meet this requirement when submitting an application.

Position description:Research Fellow (Cancer Biology and Biochemistry) PD.doc

Applications close:1 JULY 2022 11:55 PMAUS Eastern Standard Time

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Research Fellow, Cancer Biology and Biochemistry job with UNIVERSITY OF MELBOURNE | 296107 - Times Higher Education

Biochemistry

Assistant Professor, Department of Biochemistry job with NATIONAL UNIVERSITY OF SINGAPORE | 296136 – Times Higher Education

Job Description

The National University of Singapore invites applications for an Assistant Professor for the Department of Biochemistry, Yong Loo Lin School of Medicine with an affiliation to the Healthy Longevity Translational Research Programme.

The successful candidate will be expected to:

Job Requirements

At NUS, the health and safety of our staff and students are one of our utmost priorities, and COVID-vaccination supports our commitment to ensure the safety of our community and to make NUS as safe and welcoming as possible. Many of our roles require a significant amount of physical interactions with students/staff/public members. Even for job roles that may be performed remotely, there will be instances where on-campus presence is required. Taking into consideration the health and well-being of our staff and students and to better protect everyone in the campus, applicants are strongly encouraged to have themselves fully COVID-19 vaccinated to secure successful employment with NUS.

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Assistant Professor, Department of Biochemistry job with NATIONAL UNIVERSITY OF SINGAPORE | 296136 - Times Higher Education

Biochemistry

5 For The Fight announces new cancer research fellows – Utah Business – Utah Business

Provo5 For The Fight, a nonprofit started by Qualtrics and fueled by thousands of private donors, announced today that seven new cancer researchers will get a boost for their work thanks to $1.1 million in grants.

The five women and two men, who are part of the multi-year 5 For The Fight Cancer Research Fellows program, were vetted and chosen in part for their pledge to focus on research designed to:

What these cancer researchers have in common is grit and innovation, says Mike Maughan, 5 For The Fight co-founder. Their important work along with the work of other fellows in the program brings us one step closer to our goal to eradicate cancer. We are excited to fuel their progress and help give them a real chance to advance the field and help mentor those that come after them.

This is the third class of 5 For The Fight Cancer Research Fellows, which now totals over 30 researchers. Each researcher receives funding for three years and provides updates on findings annually. 5 For The Fight also has 15 cancer centers through other grants. Past 5 For The Fight Fellows have reported progress on research in colon cancer screenings for Black and Indigenous men, the study of how and why melanomas form, and the role of B cells in solid tumors, among other achievements. To date, 5 For The Fight has raised nearly $30 million to help eradicate cancer with 100 percent of those funds donated directly to the worlds leading cancer researchers.

All seven of the new fellowship recipients are located at Huntsman Cancer Institute at the University of Utah. For information on how to donate to support future fellows as well as other cancer researchers, please visitwww.5forthefight.org

About 5 For The Fight

5 For The Fight, a nonprofit started byQualtricsin 2017, is a global campaign inviting everyone to donate $5 to the fight against cancer. Each donation is made in honor of someone who is battling or has been touched by the disease. 5 For The Fight is featured on the Utah Jazz jersey patch and is the only cause-related jersey patch in the NBA. To join the fight, please visitwww.5forthefight.org.

2022-2025

5 For The Fight Cancer Research Fellows

Robert L. Dood, MD, MSCEis fighting to improve survival rates in people with gynecologic cancers. A surgeon-scientist specializing in gynecologic cancer and an assistant professor of obstetrics and gynecology at the University of Utah, Dood will pursue research to better understand specific tumor traits, and use these findings to advance insights into more effective treatment approaches. Dood completed his medical degree and a master of epidemiology at the University of Pennsylvania, followed by fellowship training in gynecologic oncology at the University of Texas M.D. Anderson Cancer Center.

Shreya Goel, PhDis fighting to improve imaging in pediatric cancer patients. Imaging is a tool used by doctors to assess whether a patient is responding to treatment. A pediatric cancer researcher and an assistant professor of pharmaceutics and pharmaceutical chemistry, Goel will advance study of new methods of imaging for pediatric cancers. She completed her PhD in materials science at the University of Wisconsin, followed by postdoctoral training in nanomedicine and cancer systems imaging at the University of Texas M.D. Anderson Cancer Center.

Crystal Lumpkins, PhD, MAis fighting to prevent cancers and improve outcomes in African American and Black immigrant populations through genetic testing and more effective communication. A cancer population scientist and associate professor of communication, Lumpkins will test new tools to improve communication about reducing cancer risk in minority populations. Lumpkins received her doctorate from the University of Missouri-Columbia and holds masters degrees in media communications and management from Webster University in St. Louis, Missouri.

Matt Miller, PhDis fighting to understand the underlying cellular changes that can lead to cancer and other diseases. A cancer biochemist and assistant professor and assistant professor of biochemistry, Miller is working to answer fundamental questions about how microscopic changes in chromosomes can lead to defects that precipitate the development of diseases like cancer and to use these insights to inform more effective strategies for prevention and treatment. Miller received his PhD in cell biology from the Massachusetts Institute of Technology, followed by postdoctoral training in biochemistry and biophysics at the Fred Hutchinson Cancer Research Center.

Ami Patel, MDis fighting to develop better treatments that will improve outcomes for people with blood cancers. As a physician-scientist and an assistant professor of internal medicine, Patel cares for patients with leukemia and will use the fellowship award to advance development of new clinical trials to assess treatments that will target leukemia cells. She completed medical training and an internal medicine residency at Northwestern University, followed by fellowship training in hematology-oncology at the Salt Lake Veterans Affairs Medical Center and the University of Utah.

Melissa Reeves, PhDis fighting to understand how certain tumor characteristics resist treatments. Reeves oversees a cancer research laboratory and is an assistant of pathology at the University of Utah. Reeves studies a tumor trait called heterogeneity. Heterogeneous tumors respond poorly to immunotherapy, and are common across many tumor types, including melanoma, lung cancer, bladder cancer, and kidney cancer. Yet they are resistant to all available treatments. Reeves plans to understand the barriers the immune system encounters fighting heterogeneous tumors and develop treatment strategies that will improve outcomes for patients. She completed her PhD in biomedical sciences from University of California San Francisco.

Arabella Young, PhDis a cancer immunologist and assistant professor of pathology who is fighting to understand how to safely deliver immunotherapy treatments for certain types of cancer. Almost all cancers can benefit from immunotherapy treatment meaning treatments that harness a patients own immune system to fight their tumor. Yet some internal systems in the patients immune system can create resistance to treatments. Young aims to engineer strategies that safely amplify the immune response to cancer. She completed a PhD in immunology from the University of Queensland, and postdoctoral training in tumor immunology and autoimmunity from University of California San Francisco.

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5 For The Fight announces new cancer research fellows - Utah Business - Utah Business