Category Archives: Immunology

Immunology | Boston Children’s Hospital

The Division of Immunology at Boston Childrens Hospital provides evaluation and treatment for patients with asthma, allergies, immune system disorders, skin diseases and rheumatologic and inflammatory conditions.Our approach to patient care

Our experienced allergists, immunologists, dermatologists, and rheumatologists are all appointed to the Harvard Medical School faculty. They treat more than 30,000 patients each year both on our inpatient services at Boston Childrens Hospital and in our outpatient clinics located at seven sites in the greater Boston area and beyond.

In addition to our specialized physicians, our programs include a range of experienced ancillary providers, such as psychologists and nutritionists, and we work closely with subspecialists in a number of other Boston Childrens Hospital programs to provide coordinated care for our patients. Several multidisciplinary clinics are offered including the FACETS food allergy clinic as well as specialized programs for severe asthma, atopic dermatitis, multiple autoimmune diseases and dermatology and autoimmunity.

Our clinical programs are widely recognized. We are a founding site of the International Consortium for Immunodeficiency, an international referral center for children with immune system disorders and have achieved national designations as a Food Allergy Research & Education (FARE) Center of Excellence, Federation of Clinical Immunology Societies (FOCIS) Center of Excellence for immunodeficiency and a Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry site for autoimmune disorders.

The Division is a major site of NIH-funded research and is widely recognized as the leading center for clinical and basic investigation in pediatric immunology, allergy and rheumatology. We host the most sought-after Harvard Medical School-affiliated fellowship training programs for young physicians specializing in Allergy & Immunology, Pediatric Rheumatology and Pediatric Dermatology.

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Immunology | Boston Children's Hospital

Immunology – 8th Edition

Preface vii

List of Contributors ix

SECTION 1

Components of the Immune System 1

1 Introduction to the Immune System 3

David Male

2 Cells, Tissues, and Organs of the

Immune System 17

Peter M Lydyard and Nino Porakishvili

3 Antibodies 51

Roy Jefferis

4 Complement 71

B Paul Morgan

5 T Cell Receptors and MHC Molecules 89

David B Roth

SECTION 2

Modes of Immune Response 107

6 Mechanisms of Innate Immunity 109

David Male

7 Mononuclear Phagocytes in Immune

Defense 125

Luisa Martinez-Pomares and

Siamon Gordon

8 Antigen Presentation 143

David Male

9 Cell Cooperation in the Antibody

Response 157

Joseph C Marini and Kalpit A Vora

10 Cell-mediated Cytotoxicity 171

Victoria Male

11 Regulation of the Immune Response 183

David Bending

12 Immune Responses in Tissues 199

David Male

SECTION 3

Defense Against Infectious Agents 209

13 Immunity to Viruses 211

Persephone Borrow and Anthony A Nash

14 Immunity to Bacteria and Fungi 223

Gregory J Bancroft

15 Immunity to Protozoa and Worms 243

Richard J Pleass

16 Primary Immunodeficiencies 263

Luigi D Notarangelo

17 AIDS, Secondary Immunodeficiency

and Immunosuppression 277

Dean H Kedes and Lisa A Nichols

18 Vaccination 289

Colin Casimir

SECTION 4

Immune Responses Against Tissues 305

19 Immunological Tolerance 307

Thomas Kamradt

20 Autoimmunity and Autoimmune

Disease 323

James E Peters and David A Isenberg

21 Transplantation and Rejection 341

Andrew J T George

22 Immunity to Cancers 355

Pramod K Srivastava

V

SECTION 5

Hypersensitivity 369

23 Immediate Hypersensitivity (Type I) 371

Thomas A E Platts-Mills

24 Hypersensitivity (Type II) 393

David Male

25 Hypersensitivity (Type III) 405

David P DCruz

26 Hypersensitivity (Type IV) 419

Warwick J Britton

Appendices online

1. Major Histocompatibility Complex

2. CD System

3. The Major Cytokines

4. Human Chemokines and Their Receptors

Critical thinking: Explanations 433

Glossary 445

Index 455

vi

Contents

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Immunology - 8th Edition

Home – CAS – Undergraduate Immunology Program | UAB

Immunology at UAB is an interdisciplinary program between the Department of Microbiology in the School of Medicine and the Department of Biology in the College of Arts and Sciences. It provides an immunology-focused curriculum in addition to a broad-based education in the fundamental aspects of biology, microbiology, chemistry, physics, and mathematics. This curriculum will satisfy most pre-medical and pre-health requirements, making it an ideal choice for those students who have an interest in pursuing careers in:

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Home - CAS - Undergraduate Immunology Program | UAB

Home [immunology.ucsd.edu]

UC San Diego and the La Jolla Institute's unique partnership fosters shared research interests, collaboration, and the application of young scientists to all aspects of host immunity, with the goal of advancing immunological research and further distinguishing the San Diego region as a leader in the field.

The Program converges diverse individual and departmental research efforts from 86 laboratories at UC San Diego's Division of Biological Sciences and School of Medicine and the La Jolla Institute, to cultivate interdisciplinary alliances and effect clinical translation of Immunology research. Our collaboration encompasses a nascent Graduate Program, a Seminar Series, andCollaborative Pilot Grants for joint research projects between UC San Diego and the La Jolla Institute, and applications for postdoctoral and predoctoral training grants.

The Program in Immunology is a collaborative effort joining the resources, faculty, and laboratories of the La Jolla Institute and UC San Diego.

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Home [immunology.ucsd.edu]

Immunology and Microbiology Concentration Graduate …

NOTE: This page is for detailed information about the Immunology & Microbiology Advanced Concentration only. All inquiries concerning admission to the BMS must be directed to the BMS Admissions office at biomed@med.ufl.edu. More information on admissions is also available on the Admissions Page.Overview

The Advanced Concentration in Immunology and Microbiology is one of eight advanced concentrations leading to the Ph.D. degree under the auspices of the Graduate Program (BMS) in Biomedical Sciences at the University of Florida College of Medicine.

The Immunology and Microbiology program offers graduate training in cellular and molecular immunology including immunopathology, immunogenetics, and autoimmunity and in microbiology, including virology, bacteriology, microbial genetics, and microbial pathogenesis.

The program is designed for maximum flexibility in the educational experience of the individual student and provides broad opportunities for training in immunology and microbiology, emphasizing both the cellular and molecular aspects. Following admission, students complete a year of common interdisciplinary core curriculum of classroom studies. In addition, the students participate in seminars, journal clubs, and research rotations. At the end of the first year students choose a research advisor from approximately 200 faculty members belonging to the basic science departments of the College of Medicine and the College of Dentistry.

The faculty members of the Immunology & Microbiology advanced concentration occupy research space in the College of Medicine, College of Dentistry, and Veterans Administration Medical Center in Gainesville.

Learn about David Bloom, Ph.D.s work on novel therapy development for Herpes Simplex Virus (HSV).

Dr. Bloom has one of the College of Medicines training grants for Basic Microbiology and Infectious Disease (T32AI007110-32).

Students interested in pursuing bacteriology, virology or immunology research as a student in the Immunology & Microbiology advanced program are strongly encouraged to register in the spring semester of their first year for two, semester-long courses: Infectious Diseases (GMS 6121 3 credits) and Principles of Immunology (GMS 6140 4 credits). A major impetus for students to participate in both courses simultaneously is the significant integration between the classes that will be included in the twice weekly discussion sessions. It is our goal that these courses will provide the foundation for each aspect of our advanced curriculum. We expect students in the advanced courses of all MSI three tracks (Bacteriology, Immunology, and Virology) to have the knowledge obtained from these two courses.

First-year students with very strong backgrounds in immunology and/or microbiology may begin taking advanced courses after discussing their educational background and goals with an Advanced Concentration Co-Coordinator the Associate Dean for Graduate Education. Instructors consent must be obtained before registering for courses.

Suggested Courses for Advanced Students: Most Immunology & Microbiology students are expected to take about four of the six minimum required credits of advanced coursework within the Immunology & Microbiology concentration offerings, but the final selection is determined by the student and approved by the students supervisory committee. Advanced graduate courses are organized by the Immunology & Microbiology advanced concentration and may be taken to fulfill the minimum advanced course requirement of at least 6 credits beyond the first year are listed at the following two web pages:

Fall Semester Advanced Courses | Spring Semester Advanced Courses

GMS 6038, Bacterial Genetics & Physiology (1 credit) is offered in the Fall. GMS 6121, Infectious Diseases (3 credits), a comprehensive introduction to bacteriology and bacterial pathogenesis including a week each of virology and mycology, is offered in the Spring and Fall.

The Pathobiology Department at the College of Veterinary Medicine offers a three pack of advanced modules focused on the molecular pathogenesis of specific parasitic or bacterial diseases (see VME 6464 & VME 6934) in the Spring. Additional Spring courses include GMS 6040, Host-Pathogen Interactions (1 credit) and GMS 6169, Special Topics Antimicrobial Strategies (1 credit).

A three pack of advanced modules is offered in the Spring (GMS 6034, GMS 6035, GMS 6036). Fall semester advanced modules will include: GMS 6382, Special Topics in Immunology; VME 6505, Autoimmunity; and GMS 6040, Host-Pathogen Interactions.

Journal Club: The Immunology & Microbiology journal club meets each Thursday at 12:00-1:00 p.m. during the Fall semester. All Immunology & Microbiology students are required to register for the Immunology & Microbiology journal club (GMS 6921, Immunology/Microbiology Journal Colloquy) each Fall semester beginning in their second year. Most Fall semester journal club presentations are usually based on a general theme, e.g. vaccines, immune response to infection, emerging pathogens.Immunology & Microbiology students must also register for a journal club in the Spring semester, but they may register for the specialty journal club of their choice, e.g. immunology, bacteriology, virology, HIV, etc.

Meet David Ostrov, Ph.D. and learn about his research on proteins and the identification of druggable targets:

For a list of faculty members currently recruiting graduate students in the Immunology & Microbiology advanced program for 2017-2018, please click here.

For a list of faculty all members in the Immunology & Microbiology advanced program, please click here.

Co-Coordinators, Immunology & Microbiology Advanced Concentration

Scott Tibbets, Ph.D.Graduate CoordinatorDepartment of Molecular Genetics and MicrobiologyPhone: (352) 273-5628 | Email: stibbe@ufl.edu

Clayton E. Mathews, Ph.D.Graduate CoordinatorDepartment of Pathology, Immunology and Laboratory MedicinePhone: (352) 273-9269 | Email: cxm@ulf.edu

Mary-Ellen Davey, Ph.D.Graduate CoordinatorDepartment of Oral BiologyPhone: (352) 273-8858 | Email: MDavey@dental.ufl.edu

Kristyn MinkoffGraduate AdministratorPhone: (352) 273-6380 | Email: MGM-GradEd@mgm.ufl.edu

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Immunology and Microbiology Concentration Graduate ...

S2 Genomics and the RIKEN Center for Integrative Medical Sciences Collaborate on Single-Cell Genomics on Solid Tissues – Financialbuzz.com

S2 Genomics, a manufacturer and provider of automated tissue sample preparation systems, and the RIKEN Center for Integrative Medical Sciences (IMS), a leading genomics research institute, today announced that RIKEN IMS has joined the S2 Genomics Early Technology Access Program to evaluate and further develop single cell sequencing applications on the S2 Genomics Singulator tissue preparation system.

Achieving high-quality single cell data from solid tissues relies upon consistent and reproducible cell or nuclei dissociation procedures. To overcome the challenges often seen with manual cell dissociation methods, S2 Genomics has developed the automated Singulator system to process solid tissue samples into suspensions of cells or nuclei for single-cell analysis.

Current methods of cell isolation are a significant bottleneck for researchers and can lead to inconsistencies in their data. The Singulator automates and standardizes the dissociation of solid tissues and can improve the quality of single-cell and single-nuclei data from a variety of solid tissue types, said Dr. Stevan Jovanovich, President and CEO of S2 Genomics. We are excited to work with the RIKEN IMS to evaluate the performance of the system and to develop new applications for the Singulator platform.

Dr. Aki Minoda, Unit Leader of the Epigenome Technology Exploration Unit, commented on the collaboration: We are delighted to collaborate with S2 Genomics and incorporate the Singulator into our workflow for single-cell analyses.

About S2 Genomics, Inc.

S2 Genomics, founded in 2016, is a leading developer of laboratory automation solutions to process solid tissue for life science applications. S2 Genomics technology platforms integrate advanced fluidics, optics, and biochemistry capabilities to produce sample preparation solutions for the next generation sequencing (NGS) and cell biology markets. For more information, visit http://www.s2genomics.com.

S2 Genomics, the S2 Genomics logo, and Singulator are trademarks of S2 Genomics, Inc.

About the RIKEN Center for Integrative Medical Sciences

The RIKEN IMS aims to elucidate the pathogenesis of human diseases and establish new therapeutic methodologies by conducting cutting-edge research on human genome and immune function. To that end, we have established four Divisions: (1) Division of Genomic Medicine, (2) Division of Human Immunology, (3) Division of Disease Systems Biology, and (4) Division of Next Generation Cancer Immunology. These groups work together to promote state-of-the-art research.

For more information, visit https://www.riken.jp/en/research/labs/ims/index.html.

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S2 Genomics and the RIKEN Center for Integrative Medical Sciences Collaborate on Single-Cell Genomics on Solid Tissues - Financialbuzz.com

Make sure to get the Flu Shot even if you’ve already had the Flu – WFMYNews2.com

GREENSBORO, N.C. If you skipped this years flu shot and then came down with the virus, you may think theres no point in getting the vaccine now.

But youd be wrong.

There are good reasons to get a flu shot, even if youve already been sick this season, says David Topham, Ph.D., a professor of microbiology and immunology at the University of Rochester and director of the New York Influenza Center of Excellence.

Two types commonly make people ill: type A and type B. In the beginning of this flu season, most cases of flu in the U.S. were type B (an unusual development, because type A usually predominates in the early months of a season).

Now, it looks liketype B flu may be beginning to wane while influenza A may be on the rise. And were probably far from done with flu season. According tothe Centers for Disease Control and Preventions latest data, doctors visits due to flu-like illness are still on the rise, though the pace may be slowing. For the first week of February, flu illnesses jumped from 6.7 percent to 6.8 percent of all doctors visits, while in the last week of January, flu illnesses shot up from 5.7 percent to 6.7 percent of all doctors visits.

Flu season looks like it may be starting to level off, but its still going up for the country as a whole, says Lynnette Brammer, M.P.H., an epidemiologist with the CDCs influenza division.

Getting the flu a second time can make you just as miserable as it did the first time around. And the potential for complications with the second infection is just as great as it was with the first.

Those complications can be serious, such as pneumonia and even sepsis, a potentially deadly reaction your body can have to infection.

Flu can also harm your heart. A study published in 2018 in the New England Journal of Medicine found that an individuals heart attack risk was six times higher than usual in the seven days following a positive test for influenza.

This may be of most concern to older adults, especially those with heart disease or who are at higher risk for heart disease because of smoking, diabetes, or other factors, says Jeff Kwong, M.D., lead author of the study and a scientist at the Institute for Clinical Evaluative Sciences in Ontario.

The bottom line: If you havent had one yet,get a flu shot even if you already had the flu (or a bug you think might have been the flu). Although the vaccine doesnt guarantee that youll avoid a second case of the flu, it will reduce the likelihood of it and its complications.

If you did get the vaccine this season, theres no need to get a second one. Scientists believe the protection usually lasts for the whole season.

But if youre still getting over a respiratory illnessor any kind of bugwait until youre fully recovered before going for the flu shot, says Topham at the University of Rochester. When you have another illness, he says, your immune system is focused on the infection that you have and doesnt respond as well to a vaccine.

And keep in mind that if youre starting to recover from the flu and symptoms worsen again, this could signal a secondary infectionsuch as pneumonia,and you should call your doctor right away.

Your hygiene habits can also help stop the spread of flu. Remember to be diligent about washing your hands and covering any coughs or sneezes. Avoid touching your eyes and mouth to keep from transferring any germs that may be on your hands. Keeping air at 30 percent to 50 percent humidity by using a humidifier can help, too; dry air helps the flu virus live longer.

If you do get sick again, stay home to avoid infecting anyone else.

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The way your immune system sees them is very different, Topham says.

Two types commonly make people ill: type A and type B. In the beginning of this flu season, most cases of flu in the U.S. were type B (an unusual development, because type A usually predominates in the early months of a season).

Now, it looks like type B flu may be beginning to wane while influenza A may be on the rise. And were probably far from done with flu season. According to the Centers for Disease Control and Preventions latest data, doctors visits due to flu-like illness are still on the rise, though the pace may be slowing. For the first week of February, flu illnesses jumped from 6.7 percent to 6.8 percent of all doctors visits, while in the last week of January, flu illnesses shot up from 5.7 percent to 6.7 percent of all doctors visits.

Flu season looks like it may be starting to level off, but its still going up for the country as a whole, says Lynnette Brammer, M.P.H., an epidemiologist with the CDCs influenza division.

Getting the flu a second time can make you just as miserable as it did the first time around. And the potential for complications with the second infection is just as great as it was with the first.

Those complications can be serious, such as pneumonia and even sepsis, a potentially deadly reaction your body can have to infection.

Flu can also harm your heart. A study published in 2018 in the New England Journal of Medicine found that an individuals heart attack risk was six times higher than usual in the seven days following a positive test for influenza.

This may be of most concern to older adults, especially those with heart disease or who are at higher risk for heart disease because of smoking, diabetes, or other factors, says Jeff Kwong, M.D., lead author of the study and a scientist at the Institute for Clinical Evaluative Sciences in Ontario.

The bottom line: If you havent had one yet, get a flu shot even if you already had the flu (or a bug you think might have been the flu). Although the vaccine doesnt guarantee that youll avoid a second case of the flu, it will reduce the likelihood of it and its complications.

If you did get the vaccine this season, theres no need to get a second one. Scientists believe the protection usually lasts for the whole season.

But if youre still getting over a respiratory illnessor any kind of bugwait until youre fully recovered before going for the flu shot, says Topham at the University of Rochester. When you have another illness, he says, your immune system is focused on the infection that you have and doesnt respond as well to a vaccine.

And keep in mind that if youre starting to recover from the flu and symptoms worsen again, this could signal a secondary infection such as pneumonia,and you should call your doctor right away.

Your hygiene habits can also help stop the spread of flu. Remember to be diligent about washing your hands and covering any coughs or sneezes. Avoid touching your eyes and mouth to keep from transferring any germs that may be on your hands. Keeping air at 30 percent to 50 percent humidity by using a humidifier can help, too; dry air helps the flu virus live longer.

If you do get sick again, stay home to avoid infecting anyone else.

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Make sure to get the Flu Shot even if you've already had the Flu - WFMYNews2.com

Vanishing Twin releasing new EP to help fund upcoming North American tour (stream it) – Brooklyn Vegan

To help fund theirupcoming North Americantour, eclectic London-based band Vanishing Twin are selling a new 7 EP,In Piscina!, featuring four groovy instrumentals of the space age bachelor pad variety, It makes for a nice companion piece to last years fantasticAge of Immunology. Stream the EP and last years album below.

Vanishing Twins tour kicks off in Austin for SXSW, and hits Los Angeles, San Francisco, Portland, Seattle, Vancouver, and Philadelphiabefore wrapping up in NYConApril 1 at Berlin. Head below for all dates.

Vanishing Twin 2020 Tour Dates17-20 March, SXSW, Austin, TX22 March, Echoplex, LA23 March Rickshaw Stop, SF25 March, Treefort Music Festival, Boise26 March, Doug Fir Lounge, Portland27 March, High Dive, Seattle28 March, Biltmore Cabaret, Vancouver30 March, Kung Fu Necktie, Philly01 April, Berlin, NYC

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Vanishing Twin releasing new EP to help fund upcoming North American tour (stream it) - Brooklyn Vegan

NIH study supports new approach for treating cerebral malaria – National Institutes of Health

News Release

Tuesday, February 18, 2020

Findings suggest drugs targeting immune cells may help treat deadly disease mainly affecting children.

Researchers at the National Institutes of Health found evidence that specific immune cells may play a key role in the devastating effects of cerebral malaria, a severe form of malaria that mainly affects young children. The results, published in the Journal of Clinical Investigation, suggest that drugs targeting T cells may be effective in treating the disease. The study was supported by the NIH Intramural Research Program.

This is the first study showing that T cells target blood vessels in brains of children with cerebral malaria, said Dorian McGavern, Ph.D., chief of the Viral Immunology and Intravital Imaging Section at the NIHs National Institute of Neurological Disorders and Stroke (NINDS) who co-directed the study with Susan Pierce, Ph.D., chief of the Laboratory of Immunogenetics at the National Institute of Allergy and Infectious Diseases (NIAID). These findings build a bridge between mouse and human cerebral malaria studies by implicating T cells in the development of disease pathology in children. It is well established that T cells cause the brain vasculature injury associated with cerebral malaria in mice, but this was not known in humans.

More than 200 million people worldwide are infected annually with mosquito-borne parasites that cause malaria. In a subset of those patients, mainly young children, the parasites accumulate in brain blood vessels causing cerebral malaria, which leads to increased brain pressure from swelling. Even with available treatment, cerebral malaria still kills up to 25% of those affected resulting in nearly 400,000 deaths annually. Children who survive the infection will often have long-lasting neurological problems such as cognitive impairment.

The researchers, led by Drs. Pierce and McGavern, examined brain tissue from 23 children who died of cerebral malaria and 11 children who died from other causes. The scientists used state-of-the-art microscopy to explore the presence of cytotoxic lymphocytes (CTLs) in the brain tissue samples. CTLs are a type of T cell in our immune system that is responsible for controlling infections throughout the body.

Current treatment strategies for cerebral malaria focus on red blood cells, which are thought to clog blood vessels and create potentially fatal blockages leading to extreme pressure in the brain. However, findings in the mouse model demonstrated that CTLs damage blood vessels, leading to brain swelling and death. The role of CTLs in cerebral malaria in children hasnt been thoroughly investigated prior to this study.

The results of the current study demonstrate an increased accumulation of CTLs along the walls of brain blood vessel in the cerebral malaria tissue samples compared to non-cerebral malaria cases. In addition, the CTLs were shown to contain and release effector molecules, which damage cells, suggesting that CTLs play a critical role in cerebral malaria by damaging the walls of brain blood vessels.

The disease appears to be an immunological accident in which the CTLs are trying to control a parasitic infection but end up injuring brain blood vessels in the process, said Dr. McGavern.

In separate studies we discovered that treatment of mice with a drug that targets T cells rescued over 60% of otherwise fatal cases of experimental cerebral malaria, said Dr. Pierce. Given our findings of T cells in the brain vasculature of children who died of the disease, we are excited by the possibility that this drug may be the first therapy for cerebral malaria.

The impact of HIV coinfection on the risk of developing cerebral malaria is not known. The NIH researchers compared CTL patterns in the cerebral malaria cases that were co-infected with HIV and those that were HIV negative. In the HIV-negative cases, the CTLs were seen lining up against the inside wall of brain blood vessels. In the HIV-positive cases, the CTLs had migrated across the surface to the outside of the vessels. There were also significantly more CTLs present in the HIV-positive cases.

Together these findings suggest that CTLs may play an important role in cerebral malaria and that HIV infection may worsen the disease.

Additional research is needed to uncover the role of T cells in human cerebral malaria. Future studies will also investigate how targeting T cells may help treat the disease. Plans for a clinical trial are underway to test the effects of a specific T cell blocker in cerebral malaria patients in Malawi.

The NINDSis the nations leading funder of research on the brain and nervous system.The mission of NINDS is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

NIAID conducts and supports research at NIH, throughout the United States, and worldwide to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID website.

About the National Institutes of Health (NIH):NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

NIHTurning Discovery Into Health

Riggle et al. CD8+T cells target cerebrovasculature in children with cerebral malaria. Journal of Clinical Investigation.

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NIH study supports new approach for treating cerebral malaria - National Institutes of Health

QIMR Berghofer researcher appointed to help guide childhood nutrition initiative – Mirage News

QIMR Berghofer Associate Professor Severine Navarro has been appointed to the steering committee of the Woolworths Centre for Childhood Nutrition Research.

The centre, which was launched by the Childrens Hospital Foundation in Queensland in 2018, aims to better understand key issues in childhood nutrition and how to tackle them.

Associate Professor Navarro is the head of the Mucosal Immunology Laboratory at QIMR Berghofer Medical Research Institute and her research focuses on the link between gut health and the immune system.

She was the first person to receive funding through the Woolworths Centre for Childhood Nutrition Research for her work into how parasites affect our gut microbiome and how they might help prevent a range of inflammatory conditions from allergies to mental illnesses.

The Centre is also funding Associate Professor Navarro to conduct research into the link between diet and gut health during pregnancy and early childhood.

I am delighted to be appointed to the steering committee for the Woolworths Centre for Childhood Nutrition Research, and to help further important studies into how we can safeguard the health of future generations, Associate Professor Navarro said.

The Centre is advancing important research into child health including the prevention and management of food allergies, diet, childhood eating behaviours and infant feeding, and I am proud to play a part in that.

I am also very grateful to the Centre for supporting my research in this field.

Associate Professor Navarro was also recently appointed the head of the Queensland branch of the Australia and New Zealand Society for Immunology the leading scientific group for immunology research in Australia and New Zealand.

In the last 10 to 15 years, immunology has emerged as a breakthrough field of research, with implications for all aspects of human health including inflammation, mental health and cancer risk and recovery, she said.

There is a lot more to learn, and as the head of the Queensland branch of the ASI, I am very pleased to support and promote this important field of research.

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QIMR Berghofer researcher appointed to help guide childhood nutrition initiative - Mirage News