Category Archives: Physiology

Physiology

Research Associate in Design Analytics and Music Physiology job with KINGS COLLEGE LONDON | 304739 – Times Higher Education

Job description

This is an exciting opportunity for a data scientist with strong musical sensibilities to play a key role in the development of computational tools for remodelling music expressivity to achieve specific cardiovascular (autonomic) aims. The objectives will be to design and implement techniques to morph expressive music parameters in ways that powerfully impact listener perception and physiology in targeted ways, to evaluate these strategies and their effectiveness, and to develop algorithms to analyse users design decisions to learn from their choices.

The work will be carried out in the context of the ERC project COSMOS (Computational Shaping and Modeling of Musical Structures), augmented by the Proof-of-Concept project HEART.FM (Maximizing the Therapeutic Potential of Music through Tailored Therapy with Physiological Feedback in Cardiovascular Disease), on citizen/data science approaches to studying music expressivity and on autonomic modulation through music. See https://doi.org/10.3389/fpsyg.2022.527539.

The remodelled expressions will be rendered synthetically or through the projects reproducing piano. Effectiveness of the expression remodelling at achieving the physiological aims will be tested on listeners, for example, through the HEART.FM mobile app tracking their physiology whilst they listen to the remodelled music. Successful transformations will be integrated into CosmoNote (https://cosmonote.ircam.fr), the web-based citizen science portal of COSMOS, or a sister web application for widespread public deployment. Collaborative designs may be explored.

The successful candidate will make major contributions to, and be involved in, all aspects of the computational modelling, interaction design, and software development; testing and validation, including on listeners (healthy volunteers or patients); and, development of algorithms for the design analytics, liaising with other research team members, and with collaborators across multiple domains, and be able to prioritise and organise their own work to deliver research results.

The successful candidate will have a PhD in computer science or a closely-related field, ideally with experience in human-computer interaction, sound and music computing (including programming with MIDI), or web programming (Javascript: D3.js). They should demonstrate a strong ability to design and implement computational algorithms to solve problems with objectives and constraints, and possess sound musical judgement.

They should be highly motivated, and have strong communication skills and a good track record of scientific publication. Personal integrity, a strong work ethic, and a commitment to uphold the highest standards in research are essential attributes.

The project is hosted by the Department of Engineering in the Faculty of Natural, Mathematical & Engineering Sciences and the School of Biomedical Engineering & Imaging Sciences (BMEIS) in the Faculty of Life Sciences & Medicine (FoLSM) at Kings College London. KCL was ranked 6th nationally in the recent Research Excellence Framework exercise. FoLSM was ranked 1st and Engineering was ranked 12th for quality of research.

The research will take place in BMEIS at St Thomas Hospital and Becket House, on the south bank of the River Thames, overlooking the Houses of Parliament and Big Ben in London.

This post will be offered on a fixed-term contract for 12 months (renewable to 31 May 2025)

This is a full-time post

Key responsibilities

Key responsibilities and outcomes

Designing and developing computational algorithms and sandbox environments to remodel musical expressivity with targeted physiological outcomes

Evaluating and validating the proposed methodologies and assessing their effectiveness and potential for clinical translation

Integrating the expression transformation tools into sandbox environments for the web in collaboration with other software programmer(s)

Following the principles of good software design, development, and documentation practices

Preparing high-quality manuscripts for publication, writing clearly about the computational techniques, outcomes, and design analytics

Presenting key findings at scientific conferences and public engagement events

Maintaining suitable performance levels for the software, following good software design, development, and documentation practices

General

Demonstrate collaborative approach to research and software development

Liaise directly with internal / external colleagues in an independent manner

Use initiative, discretion, knowledge and experience in planning, coordination and problem-solving

Demonstrate ownership of tasks and development of solutions to problems

Governance

Maintain an awareness and observation of ethical rules and legislation governing the storage of projected data

Maintain an awareness and observation of confidentiality agreements with collaborators and external organisations

Maintain an awareness and observation of appropriate procedures for the disclosure and protection of inventions and other intellectual property generated as part of the post holders activities and other team members working within the project

Development

To attend regular project meetings and training courses for professional and personal development as required

Communication & Networking

Develop and maintain effective working relationships with staff within the School as well as externally

Regularly communicate information in a clear and precise way

Decision Making, Planning & Problem Solving

Lead in decisions that have a significant impact on their own work, that of others and be party to collaborative decisions

Manage own workload, prioritising these in order to achieve their objectives

Communicate to management any difficulties associated with carrying out work tasks

Resolve problems where the solution may not be immediately apparent and where there is a need to use judgement to achieve resolution

Plan in advance for heavy workload

Use own initiative and creativity to solve problems

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Skills, knowledge, and experience

Essential criteria

1. PhD in operations research, statistics, computer science, music computing, or a related field

2. Experience designing/adapting computational algorithms to solve problems with objectives and constraints

3. Strong musical sensibilities, adaptable, willingness to learn, motivated to work with real-world music and physiological data

4. Good knowledge of software design principles and code management on Git

5. Excellent written and oral communication skills

6. Track record of high-quality, peer-reviewed scientific publications

7. Ability to work with people from diverse backgrounds and specialties

Desirable criteria

1. Experience with music software and related file formats and protocols

2. Experience programming graphical user interfaces to alter music properties

3. Hands on experience working with sound and music

Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

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Research Associate in Design Analytics and Music Physiology job with KINGS COLLEGE LONDON | 304739 - Times Higher Education

Physiology

Pioneering Engineer-Researcher to Receive 2022 Szent-Gyrgyi Prize for Progress in Cancer Research – Business Wire

ROCKVILLE, Md.--(BUSINESS WIRE)--The National Foundation for Cancer Research (NFCR) announced today that Rakesh K. Jain, Ph.D., has been selected to receive the 2022 Szent-Gyrgyi Prize for Progress in Cancer Research. The blue-ribbon Prize selection committee, consisting of renowned leaders in cancer research, elected Dr. Jain for his pioneering research and breakthrough discoveries on overcoming barriers posed by the tumor microenvironment (TME) which led to the improved delivery and efficacy of anti-cancer medicines. His groundbreaking and innovative research has fundamentally transformed the understanding of tumor biology and directly informed the development and approval of new drug-combinations to treat cancer patients.

Rakesh K. Jain, Ph.D., will be honored at the Szent-Gyrgyi Prize award ceremony on October 22, 2022, at The National Press Club in Washington, D.C.

Dr. Jain is the director of the Edwin L. Steele Laboratories for Tumor Biology at the Massachusetts General Hospital and the Andrew Werk Cook Professor of Radiation Oncology at Harvard Medical School. In four decades of pioneering work Dr. Jain, an engineer by training continues to combine physical sciences, engineering, mathematical modeling, physiology, biology, and immunology at the laboratory bench and patients bedside to develop and support his seminal hypotheses on how the abnormal TME the surrounding blood vessels, immune cells, other cells such as fibroblasts, and the extracellular matrix thwarts the delivery and efficacy of conventional and emerging anticancer medicines and how to overcome this challenge.

By developing innovative imaging technologies and laboratory models, Dr. Jain has demonstrated in real-time that tumors have structurally and functionally abnormal blood vessels in addition to impaired lymphatics. These vascular abnormalities lead to high interstitial fluid pressure and poor blood flow that impair the delivery of antitumor therapeutics and immune cells. Moreover, the resulting abnormal TME compromises the efficacy of drugs and immune cells even after they accrue in tumors.

In light of these findings, Dr. Jain proposed the groundbreaking concept that normalizing the abnormal tumor vessels using anti-angiogenic approaches originally developed to inhibit formation of blood vessels can create a window of opportunity or time period thereby allowing better delivery and efficacy of anti-cancer medicines. Dr. Jain and his clinical collaborators demonstrated that anti-angiogenic agents could indeed normalize tumor blood vessels in patients. Indeed, brain, lung, liver, and breast cancer patients survived longer when blood flow or oxygen levels increased in their tumors due to normalization.

Dr. Jain applied his vascular normalization principle to improve the efficacy of the new immunotherapy immune-checkpoint blockade. His seminal pre-clinical work laid the foundation for clinical trials and U.S. Federal Drug Association (FDA) approval of seven combinations of anti-angiogenic drugs with checkpoint blockers to enhance their efficacy in lung, liver, endometrial, and kidney cancer patients.

Rakesh K. Jain, Ph.D., has the rare distinction of being elected to all three U.S. National Academies Sciences, Engineering, and Medicine and the National Academy of Inventors. In 2016, he received the 2013 U.S. National Medal of Science (for biological science) from President Obama our nations highest honor for advancing the fields of science.

Dr. Jains ingenious use of new experimental approaches and what they have told us about the fundamental aspects of the TME and how they can be modulated to allow more efficacious therapies for cancer are just stunning to me as an immunologist, said Mark M. Davis, Ph.D., Chair of the 2022 Prize selection committee and co-winner of the 2021 Szent-Gyrgyi Prize. His work is both deeply impactful and elegant.

Co-Chair of the 2022 selection committee and 2021 Prize co-winner, Tak W. Mak, Ph.D., remarked, The basic discoveries by Dr. Jain of the abnormal vasculature and matrix and their effects on immune cell modulation have facilitated the development of life-extending therapies. I look forward to future combinations of therapies stemming from the fruits of his incredible accomplishments.

Dr. Rakesh Jains seminal discoveries in basic and translational research have guided numerous fields in cancer research with the promise of saving lives. These are the pillars of the Szent-Gyrgyi Prize, said Sujuan Ba, Ph.D., co-chair of the 2022 Prize selection committee and President and CEO of NFCR. Incidentally, Dr. Jain has been continuously funded by the NFCR since 1998. We are delighted and proud that he is receiving the 2022 Szent-Gyrgyi Prize.

I am enormously honored and pleased to be selected by the committee for the coveted Szent-Gyrgyi Prize, stated Dr. Rakesh Jain. Every scientists dream is that his or her findings will someday translate from bench to bedside. I have been very fortunate to see this happen in my career multiple times. I have had the good fortune to collaborate with so many talented students, clinicians, other world leaders, and of course, patients who participated in the trials. Therefore, being recognized by NFCR for contributions to basic and translational oncology is an enormous honor.

About the National Foundation for Cancer Research

The National Foundation for Cancer Research (NFCR) is a 501(c)(3) non-profit organization that provides scientists in the lab the funding they need to make and apply game-changing discoveries in cancer treatments, detection, prevention and, ultimately, a cure. NFCR has distinguished itself by emphasizing long-term, transformative research often overlooked by other major funding sources and/or deemed too risky. Since its establishment in 1973, NFCR has provided more than $400 million for cancer research and public education. For more information, visit http://www.nfcr.org.

About the Szent-Gyrgyi Prize for Progress in Cancer Research

The Szent-Gyrgyi Prize for Progress in Cancer Research was established by the National Foundation for Cancer Research in honor of its co-founder, Albert Szent-Gyrgyi, M.D., Ph.D., recipient of the 1937 Nobel Prize for Physiology and Medicine. The award recognizes outstanding scientists who have expanded our understanding of cancer and cancer causation; whose vision has moved cancer research in new directions; and whose discoveries have led to advances in cancer prevention, diagnosis or treatment. Its past recipients (and their associated institutions at the time of the award) are:

The Szent-Gyrgyi Prize Dinner and Award Ceremony is part of the daylong Global Summit of Cancer Research and Entrepreneurship. Media and the public are invited and encouraged to attend. Learn more about this event.

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Pioneering Engineer-Researcher to Receive 2022 Szent-Gyrgyi Prize for Progress in Cancer Research - Business Wire

Physiology

Addressing Vitamin D issue – The New Indian Express

By Express News Service

HYDERABAD: Vitamin D is a fat-soluble Vitamin playing a vital role in human physiology. Vitamin D deficiency is prevalent worldwide. This deficiency has many consequences which are still being explored apart from the well-known skeletal complications. With the existing literature on vitamin D in India, we can understand the enormity of the problem. The prevalence of vitamin D deficiency ranged from 40% to 99% with most of the studies reporting a prevalence of 80-90%. It was prevalent in all the age groups and high-risk groups alike. With the consequences of vitamin D deficiency, namely, autoimmune diseases, cardiovascular diseases, cancer and tuberculosis being explored, we can imagine the burden it would cause in our country.

We need to create awareness amongst the public and health care providers about the importance of vitamin D and the consequences of its deficiency. Our Indian diet generally fails to satisfy the daily requirement of vitamin D for a normal adult. This stresses on the need for fortifying various foods with vitamin D, through the national programs.

The silent epidemic should be addressed with concrete public health action. The prevalence of vitamin D deficiency is high in India due to the skin complexion, poor exposure to sunlight, sunscreen cream, dietary habits, lower intake of vitamin D fortified foods. Indians are mostly vegetarians and vitamin D rich food are of animal origin.

All the above mentioned factors can be a cause in urban population. However, the rural population by virtue of their occupation have sufficient sunlight exposure, they too have low vitamin D level. This can be due to the high phytate and low calcium diet they consume. Phytate rich diet is known to reduce the intestinal absorption of calcium.

The way forwardThe following measures can be taken:

Food fortification with vitamin D is the best solution.Educational programmes are a must to create awareness about vitamin D deficiency as it is the most underdiagnosed and undertreated nutritional disease.Vitamin D supplements of good quality should be made available at PHC level for population at risk.School going children should be educated about vitamin D sufficiency, given meals, exposure to sun light and physical exercise.Testing facilities for vitamin D levels should be made affordable & accessible.Government should support research groups to study and monitor the impact of supplementation programmes and fortification strategies.

ENORMITY OF VITAMIN D DEFICIENCY IN INDIAWith the existing literature on vitamin D in India, we can understand the enormity of the problem. The prevalence of vitamin D deficiency ranged from 40% to 99% with most of the studies reporting a prevalence of 80-90%. It was prevalent in all the age groups and high risk groups alike

(The article is written by Addu Kiraannmayye, Project Nutrition Scientist B, UNICEF, National Institute of Nutrition.)

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Addressing Vitamin D issue - The New Indian Express

Physiology

AANA Foundation John F. Garde Researcher of the Year Award Presented to Jane McCarthy – Newswise

Newswise Rosemont, Ill. The American Association of Nurse Anesthesiology (AANA) Foundation presented Certified Registered Nurse Anesthetist (CRNA) Jane McCarthy, PhD, CRNA, FAAN, CAPT/USPHS (Ret.), with the John F. Garde Researcher of the Year Award during the AANA 2022 Annual Congress, August 12-16, in Chicago.

This award, which is named for former AANA Executive Director John Garde, is presented to an individual who has made a significant contribution to the practice of nurse anesthesia through clinical research. Nominees must be CRNAs who currently are or have been active in anesthesia research and can be nominated by any AANA member.

I would like to thank the AANA Foundation for this prestigious recognition of the John Garde Researcher of the Year Award. It is such an honor to be recognized in John Gardes name as he was such a mentor for me in so many ways, McCarthy said.

McCarthy earned a doctorate in physiology from the Uniformed Services University in 1985 followed by a post doctorate National Research Council Fellowship at the Navy Medical Research Institute where she did original research in high-frequency ventilation and pulmonary pathophysiology. She joined the U.S. Public Health Service Commissioned Corps as a regulatory scientist for the Food and Drug Administration (FDA) reviewing respiratory and anesthesia medical device applications for FDA approval. To better meet the anesthesia healthcare needs of the Uniformed Services, she developed the congressionally mandated nurse anesthesia program for the Uniformed Services University (1993-2000), one of the first masters level nurse anesthesia programs, mentoring students in their non-clinical and clinical research. She helped develop the AANA Research in Action program, providing a method for students to have their research peer-reviewed. More recently, she has been mentoring students in evidence-based practice to apply published research results into clinical anesthesia practice.

In 1994, McCarthy was one of the first nurse anesthetists to be recognized as a Fellow in the American Academy of Nursing. She has been a member of the AANA Board of Directors and the past president and member of the Board of Directors of the District of Columbia Association of Nurse Anesthetists (DCANA). She directed the DCANA Annual Anesthesia Safety Conference for 25 years for over 200 CRNAs and students each year from around the country.

Dr. McCarthy is a tireless advocate for professionalism in nurse anesthesia and excellence in patient care, said John Nagelhout, PhD, CRNA, FAAN, in his nomination. She is ethical in all of her responsibilities and an excellent role model for our nurse anesthesia colleagues and students. Dr. McCarthy approaches her duties with thoughtfulness, humor and applies innovative approaches to the many aspects of her academic, clinical and leadership roles.

She currently is a professor at the University of North Florida, where she does primarily online education in Healthcare Policy and Evidence-Based Practice for doctoral nursing students.

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AANA Foundation John F. Garde Researcher of the Year Award Presented to Jane McCarthy - Newswise

Physiology

Op-Ed: Central Bucks should rethink Growth & Development lesson format – The Intelligencer

By Taura Kilroy| The Intelligencer

Last year, the Central Bucks School District offered the following Growth & Development lesson options: girls lesson, boys lesson, private viewing of materials or opt out.

When a transgender or non-binary student asked if they could attend the single-sex lesson of their choosing, they were told that they must learn the lesson that coincides with their physical form and not their gender identity.

This, at its core, isnt necessarily wrong. It is very important to not skip the content that pertains to ones personal organs. There is a strong case to be made that our LGBTQ+ population of students would benefit from receiving both lesson contents. But it is a sensitive topic and needs to be handled with sensitivity. The district needs to take a closer look at its policy and offerings. The way we approach this lesson needs an update to fit our ever-changing student body population.

I believe that our children should be given the option to choose the safest and most comfortable learning environment for their personal needs. What we need to do is ensure that there are enough options to accomplish the learning objective and also respect each choice.

So if a female-born student says they prefer a girls-only lesson, we need to respect that and give them a lesson with only students with the same physiology. Now if one of those students is born female and identifies as a male and this is common knowledge, they belong there. They are 100% welcome and included. And I will go far out of my way to make it known that we accept them and they deserve to be here just as much as the other female organ students in the room. The way I approach this encourages acceptance of differences.

So let's look at a more reasonable list of offerings. I would suggest:

Coed viewing of the educational video and then break-out groups for Q&A. For the breakout groups offer a coed option with one male and one female instructor, plus female only and male only options.

Private viewing of the video followed by a Q&A with a safe adult.

An opt-out option with a parent's signature that clearly states that the parent is expected to cover the topic in some form. This form would include checkboxes with reasoning for opting out and their intended method of delivery of information.

For the opt-out version, I suggest parents can check two different boxes.

1.) They can handle this topic privately at home and use a packet provided by the school as an educational guide. I would consider a follow-up call to check in and ask how it went. Ask if there was anything that they felt they didnt know how to answer that you could offer assistance with. This shows that you care and that you are holding them to their promise. It is protecting the childs right to information and promoting an encouraging environment.

2.) They can speak with a medical professional to better address specific physical needs. This option is not just reasonable for trans students but also for disabled students, students with other 504 MDE needs, or students with underlying health issues that none of us is aware of in their private life. Recognizing that some cases are very specific and may be better handled outside of the school with a professional specialist is also important.

The form should be set up with a space for the student to select their preferred lesson style first and then sent home for the parent to view and discuss which option the parent would prefer. They can change their choice at home but I believe the child's choice should be selected first so that they feel heard. The parent then signs off and returns the permission slip.

These options cover a wider variety of individual needs. The companies that produce these educational materials provide three versions of the material. They always produce both single-sex videos and a coed video of age appropriate material.

By ensuring that all students view the coed video we are sure they are all getting the same basic content. Allowing the students to choose their peer group for the Q&A is protecting their rights to privacy and providing them with options for a safe and caring environment that fits their needs.

I think these offerings protect our students' right to privacy and create a more conducive environment for learning, acceptance, sensitivity, and safety.

Taura Kilroy lives in Chalfont and is the mother of two elementary school students in the Central Bucks School District. She also 12 years experience as an Elementary Health & PE Teacher in Great Valley School District in Delaware County.

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Op-Ed: Central Bucks should rethink Growth & Development lesson format - The Intelligencer

Physiology

Scientists Finally Revealed the Heartbeat of the Largest Animal in the World – Nature World News

One of the tiniest mammals in the world, the Etruscan shrew, has a heartbeat that may reach 1,500 beats per minute or 25 beats per second.

In contrast, the human heart beats slowly, only 60 to 100 times per minute.

The largest mammal to have ever lived, the blue whale, also had its heartbeat examined.

These marine monsters can reach lengths greater than two school buses, and their hearts, which weigh more than 1,000 pounds and are about the size of a couch, beat as little as twice every minute.

(Photo : Thomas Kelley/Unsplash)

When the animal dove, its heartbeat was gentle, but when it surfaced to breathe, the rate suddenly increased and reached as high as 37 beats per minute, as per Vox.

Scientists have developed a method to hear the heartbeats of wild whales in recent years.

They aren't particularly interested in monitoring these animals' health; rather, they are attempting to provide an answer to one of biology's most fundamental questions: how big can an animal grow on Earth?

The larger-than-dinosaur blue whales' heart rates suggest that heart size may be a limiting factor for body growth.

And with more sophisticated monitoring equipment, could also assist researchers in defending these marine giants from one of the ocean's most enigmatic dangers.

Larger hearts beat more slowly and replace the body's oxygen supply more slowly.

As a result, whales must spend more time at the surface to catch their breath, taking away from the limited time they have to consume a seasonal food source like krill.

These behemoths might not have enough time to eat if their hearts are too large.

Theoretically, these organs should be reaching their maximum speed when the whales come up for air if the size of their hearts is restricting them in any way.

When researchers went out to detect a blue whale's heartbeat in 2018, one of their goals was to learn this.

These creatures have two separate heart rates, according to blue whale heart rate statistics.

The whale is diving and trying to preserve oxygen, which is when the heartbeat is slow. The second happens quickly when the whale is back at the surface and its heart begins pumping quickly to resupply oxygen.

Big bodies may cause issues there, on the surface, as researchers had hypothesized.

Also Read: Why Do Dead Whales Explode? Experts Warn People to Run If They See This on the Beach

The use of animal-borne devices for physio-logging, which records physiological characteristics, is entering a new phase as a result of developments in sensor technology.

Existing datasets, however, gathered with conventional bio-loggers, like accelerometers, nevertheless hold latent eco-physiological data, as per Journals.

While IMU tags are easier and have fewer logistical restrictions, physio-logging tags with cutting-edge biomedical technology are pushing the limits of physiological field research.

These tags also give researchers access to more species and greater sample sizes.

This is crucial for species that cannot be restrained or researched in controlled environments.

In both managed care and the wild, the ballistocardiogram (BCG) has the potential to be used to monitor heart rate with accelerometers.

The sample rate should be carefully considered when reviewing the bio-logging data that has already been collected and when organizing the placement of new tags for BCG analysis.

As a general guideline, the sampling rate for signal processing should be at least twice as frequent as the phenomenon of interest.

The BCG waveform's frequency, not the heart rate, is the one that matters in this situation.

In humans, the IJK complex's power, which is the portion of the BCG waveform used to detect heartbeats, is focused between 4 and 7 Hz.

Due to their often larger bodies, marine mammals' BCG waveforms are unlikely to have a greater frequency than those of humans.

As a result, BCGs may be produced at accelerometer sampling rates as low as 10-15 Hz.

BGC technique may be used to mine existing datasets and better understand how heart rate scales with body size and other biological parameters as accelerometer tags have been used on numerous cetacean species for many decades.

Additionally, it might offer more information for applications in conservation physiology.

BCGs from gliding phases before and after controlled sonar exposure trials, for instance, could measure the body's reaction to anthropogenic disturbance.

Related Article: Rare Sight: Whale Gives Birth to a Calf Off the Coast of South Africa

2022 NatureWorldNews.com All rights reserved. Do not reproduce without permission.

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Scientists Finally Revealed the Heartbeat of the Largest Animal in the World - Nature World News

Physiology

ESIC Recruitment 2022: Check Posts, Eligibility and Walk-in Interview Details Here – StudyCafe

ESIC Recruitment 2022: Check Posts, Eligibility and Walk-in Interview Details Here

ESIC Recruitment 2022: Employees State Insurance Corporation (ESIC), Bengaluru has invited the Candidates with duly complete Applications and other documents Eligible for Appointment to the Posts of Senior Residents/Tutors (Anatomy/Physiology/Pharmacology/Forensic Medicine/Community Medicine) on 03-Years Contractual Basis. The Candidates fulfilling the Eligibility Criteria for the Post of Senior Resident(s) deem themselves Eligible for the Post, may fill up the Applications in the Specimen Application Proforma and report in the ESIC-Medical College Post-Graduate Institute of Medical Science and Research and Medical Hospital to attend Personal Interview and Document Verification. The Candidates may download the Specimen Application Format available on the Website.

There are 15 Vacancies for the Post of Senior Resident under different Branches mentioned in ESIC Recruitment 2022 *Note: Such Candidates who have already served under the Three-Years Senior Residency Scheme are NOT Eligible to reapply. The End Date for appearing in Walk-in Interviews befalls 26th August 2022.

ESIC Interview 2022: The ESIC Medical College PG Institute of Medical Science shall host on 26th August 2022 Walk-in Interviews for the Candidates within the ESIC Complex. The Candidates must carry with them duly completed Applications and other documents. The Candidates should carry with them the essential Documents while appearing for the Walk-in-Interview include, are Xerox of the Certificates and Documents; viz. i) Application Form, ii) 02 Most Recent Passport-size Photographs; iii) Matriculate Certificate (claiming the Date of Birth), iv) Masters (Post Graduation) Degree, PG Diploma; v) KMC/MCI Registration Certificate; vi) Caste-Community Certificate.

Service Tenure: Appointment to the Post of Senior Residents in ESIC Medical College and Post Graduate Institute of Medical Science and Research Bangalore (ESI-PGIMSR) Model College will remain for 03-Years under the Senior Residency Scheme. Such Candidates who have already served under Three-Years Senior Residency Scheme will NOT be considered Eligible for Re-appointment. However, those who already served for One Year will be appointed for only 02 Years.

Check the Details about ESIC Senior Resident/Tutors Recruitment 2022

Name of the Organization: Employees State Insurance Corporation: 15 Vacancies

Name of the Post: Senior Resident (Anatomy/Physiology/Pharmacology/Forensic Medicine/Community Medicine) on Contractual Basis (As On 26.08.2022)

Pay Emolument: Pay Band Level-11 of Rs.67700 Plus Other Allowances As Applicable under the Government of India.

01) Senior Resident (Anatomy): 03 Vacancies

02) Senior Resident (Physiology): 03 Vacancies

03) Senior Resident (Pharmacology): 03 Vacancies

04) Senior Resident (Forensic Medicine): 02 Vacancies

05) Senior Resident (Community Medicine): 04 Vacancies

Upper Age Limit: i) General Category Candidate should not exceed (Maximum) 45 Years.ii) Relaxation in Upper Age Limit for Reserved Community Candidates.

Educational Qualification: The Applicant should have in possession Post-Graduate Diploma/DNB/MD Or M.Sc. (Medical) in the concerned Specialty for Senior Resident.

Selection Process: Selection to the Post of Senior Resident will be based on the Candidates Performance in Walk-in-Interview coupled with Document Verification to the desired Eligibility Benchmark.

Service Tenure: Post-Selection Appointment to Senior Residents Tenure remains 03 Years. The Incumbent will have to deposit Non-Interest Rs. 1.25 Lac in favor of ESIC Fund A/c No.1)

Interview Details:

ESIC Medical College And PG Institute of Medical Science & Research and Model HospitalAcademic Block, Rajajinagar, Bangalore 560 010

1. Visit ESIC-MC PGIMSR Website http://www.esic.nic.in.

2. Download the Specimen Application Proforma and other Annexures. Take a Printout and Fill up the Typewritten Application,

Click Here to Read Employees State Insurance Corporations Official Notification-2022

Disclaimer: The Recruitment Information provided above is for informational purposes only. We do not provide any Recruitment guarantee. Recruitment is to be done as per the official recruitment process of the company or organization posted the recruitment Vacancy. We dont charge any fee for providing this Job Information. Neither the Author nor Studycafe nor its Affiliate(s) accepts any liabilities for any loss or damage of any kind arising out of any information in this article nor for any actions taken in reliance thereon.

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ESIC Recruitment 2022: Check Posts, Eligibility and Walk-in Interview Details Here - StudyCafe

Physiology

Brewing with Hemp: A Budding New Ingredient and a Different Kind of Haze – Craft Beer & Brewing

From esteemed brewing professional Ross Koenigs comes Brewing with Hemp: The Essential Guide, the latest release from Brewers Publications, now available at your favorite book retailers.

Brewing with Hemp by Ross Koenigs, the companion book to Brewing with Cannabis: Using THC and CBD in Beer by Keith Villa Ph.D., explores the Cannabis sativa plant from a brewers perspective, focusing on how hemp (which contains less than 0.3 percent THC), hemp flavors, and cannabinoids play in beer.

Koenigs leads readers through the history, legal considerations, physiology, and ecology of hemp, while helping professional brewers and homebrewers alike understand the science of cannabis and how to best utilize the popular plant in beer.

There are many cannabis consumers who also enjoy craft beer, and Im looking forward to sharing my vision for how hemp can be additive to an already innovative industry, said Koenigs. Through Brewing with Hemp: The Essential Guide, Ill not only take readers through the process and experimentation, but Ill also share recipes and tinctures and my experience of bringing these beers to market.

The second book in the cannabis series is perfect for homebrewers, professional brewers, enthusiasts, and appreciators of the hop plants dank cousin.

Brewing with Hemp is a book for a brewing and beverage industry audience; some hemp ingredients can be added to beer, but marijuana ingredients cannot be legally added. Learn more about the legal limitations, history of cannabis, and more with expertly researched chapters covering:

Order Brewing with Hemp: The Essential Guide directly from the publisher or your favorite independent bookseller.

Ross Koenigs is the owner of Second Dawn Brewing in Aurora, Colorado. Previously, he was the brewing innovations manager for New Belgium Brewing in Fort Collins, Colorado, where he spearheaded the research and development of using hemp in beer when New Belgium introduced The Hemperor HPA.

Brewers Publications supports the mission of the Brewers Association by publishing books of enduring value for amateur and professional brewers, as well as titles that promote understanding and appreciation of American craft beer. With more than 65 titles to choose from, Brewers Publications is the leading publisher of contemporary and relevant brewing literature for today's craft brewers, homebrewers, and beer enthusiasts.

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Brewing with Hemp: A Budding New Ingredient and a Different Kind of Haze - Craft Beer & Brewing

Physiology

How to find the right athletics coach for you | PERFORMANCE – World Athletics

Finding the right athletics coach for you is important, ensuring they provide advice that fits your needs and lifestyle, and help to create a positive, sustainable relationship with the sport.

But how to go about it? Heres our quick guide on finding the right coach for you.

Different coaches will be valuable for different people, so finding a coach who matches your needs will help get the most out of your athletics journey.

Some coaches may foster a group with a focus on making sessions as fun as possible. These coaches can be great when first finding your way into the sport, encouraging you to learn its disciplines and make you want to keep coming back.

If part of the reason you are taking up athletics is for the social interactions it creates, these coaches may be the best place to start.

Other coaches may have more of a focus on the performance side of athletics and be more appropriate for those who feel they already have an understanding of the sport and want further guidance on particular aspects of their event.

For those doing multiple disciplines, some may even choose to have more than one coach, with specialists guiding them for jumps, sprints and throws, though there are multi-discipline coaches that focus on all the events.

These performance-focused coaches can take many different forms, from experienced coaches to former athletes as well as those with a science-focused physiology background. Think of what sort of advice you would see as valuable and select your coach accordingly.

To gain a sense of the types of sessions run by coaches, take a look on social media as well as on club and coach websites, or even ask if you can do a trial session.

Many national athletics federations have a list of qualifications available to coaches on their websites.

See if the coach you hope to work with has any of these, as it will be a good indicator of the experience they have gained.

As well as these qualifications, World Athletics offers aneLearning platform, which provides educational courses and webinars for people within the sport, including those in key stakeholder groups such as technical officials, coaches and medical professionals. Further information can be found here.

Like people in everyday life, coaches will have different personalities. Some people like working with enthusiastic and loud coaches, valuing the support and clear instructions. Others prefer a softly-softly approach, with less-frequent but nonetheless valuable feedback.

Think about what you require in a coach.Speak to current group members already guided by your potential coach to gauge their personality and contemplate whether that would work for you.

Ensuring you are both on the same page will create a more positive, long-lasting and sustainable relationship for athlete and coach.

Appraise yourself honestly and think about what sort of role you see athletics playing in your life. If family, work and other life commitments may affect your training, make sure you find a coach that understands that. Be honest and up front with that coach when it comes to how you see the relationship working.

A good indicator of this will be finding a coach who works with other athletes with a similar lifestyle to you, and a good way of finding this out will be heading down to the track and trying out a few sessions for yourself.

For tips on finding the right athletics club for you and getting into track running, check out the advice here.

George Mallett for World Athletics

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How to find the right athletics coach for you | PERFORMANCE - World Athletics

Physiology

A novel method for monitoring the ‘engine’ of pregnancy | Penn Today – Penn Today

A study published in Nature Biomedical Engineering details a novel method for imaging the placenta in pregnant patients as well as the results of a pilot clinical study. By combining optical measurements with ultrasound, the findings show how oxygen levels can be monitored noninvasively and provides a new way to generate a better understanding of this complex, crucial organ. This research was the result of a collaboration of the groups of the University of Pennsylvanias Arjun Yodh and Nadav Schwartz with colleagues from the Childrens Hospital of Philadelphia (CHOP) and was led by postdoc Lin Wang.

Schwartz describes the placenta as the engine of pregnancy, an organ that plays a crucial role in delivering nutrients and oxygen to the fetus. Placental dysfunction can lead to complications such as fetal growth restriction, preeclampsia, and stillbirth. To increase knowledge about this crucial organ, the National Institute of Child Health and Human Development launched the Human Placenta Project in 2014. One focus of the program is to develop tools to assess human placental structure and function in real time, including optical devices.

For three years, the researchers optimized the design of their instrument and tested it in preclinical settings. The process involved integrating optical fibers with ultrasound probes, exploring various ultrasound transducers, and improving the multimodal technology so that measurements were stable, accurate, and reproducible while collecting data at the bedside. The resulting instrumentation now enables researchers to study the anatomy of the placenta while also collecting detailed functional information about placenta blood flow and oxygenation, capabilities that existing commercially devices do not have, the researchers say.

Because the placenta is located far below the bodys surface, one of the key technical challenges addressed by Wang, a postdoc in Yodhs lab, was reducing background noise in the opto-electronic system. Light is scattered and absorbed when it travels through thick tissues, Yodh says, and the key for success was to reduce background interference so that the small amount of light that penetrates deep into the placenta and then returns is still large enough for a high-quality measurement.

Were sending a light signal that goes through the same deep tissues as the ultrasound. The extremely small amount of light that returns to the surface probe is then used to accurately assess tissue properties, which is only possible with very stable lasers, optics, and detectors, says Yodh. Lin had to overcome many barriers to improve the signal-to-noise ratio to the point where we trusted our data.

Notably, the paper also describes the results of a pilot study where 24 pregnant patients in their third trimester were given supplemental oxygen for a short time period, creating placental hyperoxia. Using the device, the team collected measurements of the placentas oxygenated and deoxygenated blood concentrations before and during hyperoxia; the results demonstrated that the device could be used to study placental function in real time. The research also provided new insights into the relationship between blood flow and maternal vascular malperfusion, which occurs when blood flow into the placenta is impeded.

Not only do we show that oxygen levels go up when you give the mom oxygen, but when we analyze the data, both for clinical outcomes and pathology, patients with maternal vascular malperfusion did not have as much of an increase in oxygen compared to patients with normal placentas, says Schwartz. What was exciting is that, not only did we get an instrument to probe deeper than commercial devices, but we also obtained an early signal that hyperoxygenation experiments can differentiate a healthy placenta from a diseased placenta.

While the device is still in development, the researchers are currently refining their instrument to make it more user-friendly and to allow it to collect data faster. The team is also currently working on larger studies, including recently data from patients during their second trimester, and they are also interested in studying different regions of the placenta. From an instrumentation perspective, we want to make the operation more user-friendly, and then we want to carry out more clinical studies, Wang says about the future of this work. We have lots of interesting ideas.

And because there are many unanswered clinical questions about the placenta, for Schwartz the biggest potential of this work is in providing a way to start answering those questions. Without being able to study the placenta directly, we are relying on very indirect science, he says. This is a tool that helps us study the underlying physiology of pregnancy so we can more strategically study interventions that can help support good pregnancy outcomes.

The authors are Lin Wang, Jeffrey M. Cochran, Kenneth Abramson, Lian He, Venki Kavuri, Samuel Parry, Arjun G. Yodh, and Nadav Schwartz from Penn; Tiffany Ko, Wesley B. Baker, and Rebecca L. Linn from the Childrens Hospital of Philadelphia, and David R. Busch, previously a research associate at Penn and now at the University of Texas Southwestern Medical School.

Arjun Yodh is the James M. Skinner Professor of Science in the Department of Physics and Astronomy in the School of Arts & Sciences at the University of Pennsylvania.

Nadav Schwartz is an Associate Professor in the Department of Obstetrics and Gynecology in Penns Perelman School of Medicine.

Lin Wang is a postdoc in the Department of Physics and Astronomy in Penns School of Arts & Sciences.

This research was supported by National Institutes of Health grants F31HD085731, R01NS113945, R01NS060653, P41EB015893, P41EB015893, T32HL007915, and U01HD087180.

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A novel method for monitoring the 'engine' of pregnancy | Penn Today - Penn Today