Category Archives: Physiology

Let cows’ physiology guide calving check schedule – Farm Forum

By Russ Daly Professor, SDSU Extension Veterinarian, State Public Health Veterinarian

The routine calving check is one of the most important tasks on the list of beef cattle producers during calving season.

Most producers have their own plan for how often they give their calving herd the once-over, but some may have not considered how their animals physiology should guide this schedule.

Incredible advances in technology have made it easier for producers to perform calving checks.

Wireless cameras in the calving barn mean producers can monitor cows and heifers without leaving the warmth of the house.

Devices strapped to the back end of cows can send an alert to a smartphone when the calving process commences, and drones can even be used to check up on cattle in remote areas.

Labor stages and calving: Significant events

While how cattle producers check their animals may have changed rapidly in recent years what they are watching for the stages of labor and calving have not changed.

The normal progression of labor should guide how often cattle producers walk out to the calving pen, or whip out the smartphone for a look.

Of course, the most optimal frequency of observation occurs when people dont miss events too important to miss.

Some examples are:

Cows or heifers spending too much time in Stage I labor (the preparatory stage of labor). This varies greatly among cattle based on their parity, but will normally last two-to-six hours.

Stage I labor lasting more than eight hours means a greater chance the calf will be stillborn or oxygen deprived at birth.

Cows or heifers spending too much time in or giving up on Stage II labor (the delivery stage).

Once the delivery phase begins, steady progress should be made, culminating in a live calf somewhere between 30 minutes and two hours after it commences.

Signs of distress in a calf during labor, such as a swollen tongue or signs of an abnormal (backwards, breech, etc.) birth.

A live-born calf that needs timely help starting to breathe, nurse or to be protected from cold, wet conditions.

How often should you check in?

A common rule of thumb is that cows and heifers should be checked every three hours.

Comparing this to the information above, however, would indicate that should be sufficient to determine whether a cow has been messing around (stage I labor) too long, but maybe not long enough to determine whether a cow has been in the delivery phase (stage II labor) for two hours.

Many cattle producers check their calving areas less frequently than every three hours on average. This is often a compromise among labor, time and the risk of losing a calf.

Most producers also realize, however, that certain factors can result in a group needing more or less frequent observation, such as:

First-calf heifers: More frequent checking vs. older cows.

How many cows are calving: More calving means more frequent checking.

Previous indications of dystocia problems: bigger calves than expected means more frequent checking.

Weather: cold wet weather means more frequent checking, in order to assist calves after birth.

The bottom line

All beef cattle producers want to maximize the number of live calves born. Offering timely assistance to cows and heifers having problems, and providing prompt attention to newborns are some of the ways this can be done during the calving season.

As such, erring on the side of checking calving areas more often rather than less often can be a good idea.

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Let cows' physiology guide calving check schedule - Farm Forum

ACC 2017: CVD Outcomes for Evolocumab, Intermediate-Risk TAVR, Coronary Physiology Tests, and More – TCTMD

Returning to their own backyard again this year, the American College of Cardiology (ACC) 2017 Scientific Sessions kick off next Friday with high hopes of giving the world some headlines to compete with other news coming out of the nations capital. Among the hot-ticket items on this years roster are a large, cardiovascular outcomes trial for a market-approved PCSK9 inhibitor, a randomized comparison of a non-vitamin K antagonist oral anticoagulant (NOAC) against aspirin in acute coronary syndromes, and 2-year outcomes from ABSORB III, the pivotal randomized trial that led to US approval of the first bioresorbable scaffold in 2016.

According to the ACC 2017 program chairs, who spoke with media via a telebriefing last week, this years conference attracted over 2,600 abstracts, of which 114 were late-breaking clinical trial (LBCT) submissions. A full 23 of these were selected as late breakers, and an additional 17 submissions are grouped in the featured clinical research sessions. There are a total of five LBCT sessions and three featured clinical research sessions distributed throughout the 3-day congress, which runs from Friday, March 17, through Sunday, March 19.

Were incredibly excited about this upcoming meeting, Jeffrey Kuvin, MD (Dartmouth-Hitchcock Medical Center, Manchester, NH), enthused during the telebriefing. Were confident there will be numerous practice-changing science presentations.

Chief among those is shaping up to be FOURIER, the 27,500-patient cardiovascular outcomes trial testing the PCSK9 inhibitor evolocumab on top of statin therapy against statins alone for the prevention of cardiovascular death, nonfatal MI, nonfatal stroke, hospitalization for angina, or coronary revascularization. As previously reported by TCTMD, the company announced in February that the trial had met its primary and secondary endpoints, but full details on those will be released in the opening LBCT session at ACC.

This is undoubtedly going to be a widely noted study and has the potential to be truly game changing, Kuvin said

Fleshing out Fridays opening LBCT session are the SPIRE I and II results looking at cardiovascular outcomes with a second PCSK9 inhibitor, bococizumab. These trials were stopped early in late 2016 after trial monitors noticed an unanticipated attenuation of LDL cholesterol lowering over time combined with an increase in immunogenicity and injection-site reactions.

The third trial in what the ACC has dubbed its opening showcase is SURTAVI, the pivotal trial testing the CoreValve transcatheter valve (Medtronic) in intermediate-risk patients with severe symptomatic aortic stenosis. The trial, which was initially launched outside the United States and then extended to include US patients, is anticipated to pave the way for an expanded US Food and Drug Administration (FDA)-approved indication later this year.

Day two of ACC 2017 includes two LBCT sessions, the first of which is jointly hosted by the Journal of the American College of Cardiology and the Journal of the American Medical Association.

During the telebriefing, Kuvin highlighted EBBINGHAUS, a cognitive function substudy from FOURIER, as well as two NOAC studies in that session. The first of these, EINSTEIN CHOICE, is looking at rivaroxaban versus aspirin for extended treatment of venous thromboembolism, while the second, GEMINI-ACS-1, is comparing rivaroxaban and aspirin on top of P2Y12 inhibition for patients post-ACS.

ACC 2017 Vice Chair Andrew Kates, MD (Washington University in St. Louis, MO), also speaking on the media telebriefing, took over from Kuvin to list some of the highlights of the remaining two LBCT sessions. Topping Kates list was ABSORB III. When the primary results of the study were released in 2015, the Absorb BVS (Abbott Vascular) was noninferior to DES at 1 year, Kates noted, adding that severalbut not allstudies have pointed to an increased rate of scaffold thrombosis with the bioresorbable device after 1 year. What were excited about at ACC 17 is well be hearing the interval data between years 1 and 2 [as well as the] the 2-year data in this session, Kates said, adding, Certainly its going to be important data that were looking forward to hearing.

Kates highlighted a number of other key trials throughout the program. These included LEVO-CTS looking at the use of levosimendan in patients with LV systolic dysfunction undergoing cardiovascular surgery with cardiopulmonary bypass, part of Sundays LBCT IV session co-hosted by JACC and the New England Journal of Medicine. Also in LBCT IV, Kates noted, is a trial testing a cerebral protection device during cardiac surgery.

While using embolic protection devices is safe and does capture embolic material, Kates said, its really not clear whether these devices really do anything to prevent strokes, or if they may reduce cognitive decline after surgery. This is certainly a very important topic that we all care about.

Finally, from LBCT V, Kates highlighted two heart rhythm studies, RE-CIRCUIT and ARISTOTLE. The first is looking at a relatively new drug, dabigatran (Pradaxa, Boehringer Ingelheim), used without interruption during ablation for atrial fibrillation. The second is looking at an old drug, digoxin, in A-fib patients with and without heart failure.

For Interventionalists: TAVR and FFR/iFR

Interventionalists attending ACC 2017 will find plenty of other late breakers relevant to their subspecialty. Updates from transcatheter valve studies are dotted throughout the LBCT and featured clinical research sessions, including, in LBCT IV, an MRI analysis of microbleeds during TAVR and two studies looking at subclinical leaflet thrombosis in surgical and transcatheter valve prostheses. Saturdays featured clinical research session is focused on interventions and comparisons of SAVR and TAVR; transcatheter valve replacement for native versus failed surgical bioprostheses; and TAVR for bicuspid versus tricuspid valve disease. The same session also has a presentation addressing 1-year outcomes with the MitraClip (Abbott) in the US following FDA approval.

Coronary disease is also front and center, particularly in LBCT IV. This session includes a trial of culprit lesion versus complete revascularization in STEMI, plus two randomized trials of fractional flow reserve (FFR) versus instantaneous wave-free ratio (iFR): DEFINE-FLAIR and iFR-SWEDEHEART. These two large CV outcomes trials will determine how the physiologic information provided by iFR compares with the usefulness of FFR in guiding treatment.

Research and Practice

Beyond the late breakers and featured research, this years ACC has11 learning pathways including one on special topics spanning everything from malpractice minefields to public reporting. There are also seven keynote lectures, including one by Janet S. Wright, MD, executive director of the joint Centers for Disease Control/Centers for Medicare & Medicaid Services Million Hearts initiative, now perilously close to its deadline of preventing 1 million heart attacks and strokes by the end of 2017. Another keynote will be delivered by NEJM Editor-in-Chief Jeffrey Drazen, MD, speaking on data sharing in clinical trials. Drazen famously penned a controversial editorial in the journal poking holes in the Open Data proposal set forth in draft form by the International Committee of Medical Journal Editors and referring to the risk of research parasites, a position he revised in a second editorial days later.

The entire TCTMD editorial teamCaitlin Cox, Yael Maxwell, Laura McKeown, Todd Neale, Michael ORiordan, and me, Shelley Wood, will be on the ground at ACC 2017. Follow us on Twitter for breaking news and find our in-depth stories on our conference coverage page.

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ACC 2017: CVD Outcomes for Evolocumab, Intermediate-Risk TAVR, Coronary Physiology Tests, and More - TCTMD

McGill ranked world’s 3rd best university for study of Anatomy & Physiology – McGill Newsroom

McGill University is the worlds third-best university for the study of Anatomy & Physiology, behind only the Universities of Oxford and Cambridge, according to the 2017 QS World University Rankings by Subject.

The seventh edition of QS Quacquarelli Symondss analysis of subject-specific university performance, released today, lists the worlds best universities for the study of 46 different subjects. Anatomy & Physiology is one of four new subject categories introduced in this years listing.

We are extremely pleased to rank among the worlds top three universities in the study of anatomy and physiology, said David Eidelman, Vice-Principal of Health Affairs and Dean of Medicine at McGill. This is a direct outcome of the quality of our academics and staff in these departments, who I congratulate for their stellar and hard work on behalf of our students. I am also gratified to see McGills rankings rise this year in the medicine and pharmacology categories.

McGills ranking in the Medicine subject category rose to 22nd this year from 27th in 2016. In Pharmacology, McGill moved up to the 31st spot from 37th a year ago.

Another standout performance came in the Engineering Mineral and Mining category, with McGill rising to a tie for sixth place globally this year from 13th place last year. We are very proud to be ranked so highly along with our counterparts in other Canadian institutions, said Jim Nicell, McGills Dean of Engineering. The mining industry is an essential part of the economy of Canada, so we must always do our best to stay at the forefront in our teaching and research in support of this sector.

More broadly, McGill is listed this year in the top 50 in 7 of 10 subjects in Arts & Humanities, 3 of 6 subjects in Engineering & Technology, 7 of 9 in Life Sciences & Medicine, 6 of 7 in Natural Sciences, and 9 of 14 in Social Sciences & Management.

The full QS World University Rankings by Subject tables can be foundhere. The full methodology can be foundhere.

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McGill ranked world's 3rd best university for study of Anatomy & Physiology - McGill Newsroom

Behind the scenes of cardiac physiology at Salisbury District Hospital – Salisbury Journal

CARDIAC physiologists carry out a range of investigations for people with potential, or known, heart problems.

Their work includes performing electrocardiograms (ECGs), putting people on treadmills to evaluate their hearts response to exercise, performing cardiac ultrasound scans, checking and programming implanted pacemakers and implantable defibrillators, and monitoring the blood pressure and heart rhythm while stents are fitted in the cardiac catheter lab.

Claire Murray, a cardiac physiologist at Salisbury District Hospital, said: We are involved with any investigation relating to your heart. We see everybody from babies to the elderly if patients have a problem with their heart, we are involved in their care.

Cardiac physiology is one of more than 20 healthcare sciences. They involve the life sciences such as microbiology, histology and genetics, the physical sciences like medical engineering, medical physics and nuclear medicine and then the physiological sciences with people going into audiology and neurophysiology, Claire says.

Cardiac physiology is very patient-focused, which is what appealed to me.

Some of the other healthcare sciences are much more in the lab or using physics.

Cardiology is always changing theres a lot of investment into cardiac health care and theres always research going on and new developments.

We use a lot of technology and equipment and there is always something to learn which I really enjoy.

You get that feeling of really making a difference if someone comes in with a heart rate of 20 and has a pacemaker fitted, theyre instantly better. Thats so satisfying.

Procedures generally take between 10 minutes and half an hour with a cardiac physiologist writing up a report after analysing results. We are quite autonomous in our working, Claire says. For example, after doing an ultrasound, we would create a technical report on what we have found which goes back to the clinician whos asked us to do it and they will then prescribe medication or further procedures.

The most common route into cardiac physiology is a BSc in clinical physiology. Once complete, you are a healthcare science practitioner, becoming a scientist after completing the three-year Scientist Training Programme (STP).

People are educated to different levels within the scientific banner people have come in with degrees in medical engineering or microbiology, a lot of people have masters or PhDs, Claire says.

As healthcare scientists our careers have come across quite convoluted paths to get to where we are currently in the healthcare science programme.

Today, everyone will be doing science and maths as A-levels but after that point it can be very split. A lot of our scientist programmes are done as part of a national recruitment process to train people.

Previously, as a trainee cardiac physiologist, you would be employed by a hospital and do your training over four years which involved being hospital-based and going to university on block release but now you come out of university with qualifications and then look for a job.

Claires own route into the profession involved going straight from GCSEs into a two-year regional training programme.

I started in 1990, she said. The first eight months was spent in audiology, neurophysiology, respiratory physiology and cardiology. After that I chose which one and as I just loved cardiology, I spent the rest of the two years on that, doing a BTEC in medical physics and physiological measurements.

Claire has been at SDH for 15 years and is one of 12 cardiac physiologists. For any students considering a career in cardiac physiology, you have to be of scientific mind and enjoy the sciences, she says.

Its important to like working with people, you need to be prepared to talk to anybody, have excellent communication skills as we often have to explain complicated information to our patients or their carers, and have an interest in technology because everything we do is with medical equipment.

Its also about being able to keep calm in stressful situations and work as a team.

From a practical aspect, we dont tend to work shifts, although some of our role includes being on call from home, so it is very appealing from that point of view.

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Behind the scenes of cardiac physiology at Salisbury District Hospital - Salisbury Journal

How being funny changes your brain – USC News

What happens in your brain when you tell a joke? Well, that appears to depend on whether you do that for a living.

Researchers in USCs Image Understanding Laboratory studied professional improvisation comedians many from the Los Angeles Groundlings comedy troupe and amateur comics in the act of coming up with a quip. Their aim: Gain a better understanding of the neural correlates of humor creativity that is, see how the brains physiology changes when a person tries to be funny.

For the study, both pro and amateur comedians, as well as a control group of non-comedians, viewed New Yorker cartoons without words and were asked to come up with two captions for them one funny and one mundane.

Participants were scanned by functional magnetic resonance imaging (fMRI) machines to track their brain activity as they created the captions. Each comic scanned and an outside panel of participants rated each of the captions for humor.

The results showed that two regions of the brain were activated when the participants came up with jokes the medial prefrontal cortex and the temporal association regions. However, the regions activated were different depending on the persons level of expertise.

What we found is that the more experienced someone is at doing comedy, the more activation we saw in the temporal lobe, said USC doctoral student Ori Amir, who led the study with Irving Biederman, professor of psychology and computer science. The temporal lobe receives sensory information and is the region of the brain key to comprehending speech and visual cognition. Its also where abstract information, semantic information and remote associations meaningfully converge.

In contrast, the amateur comedians and non-comedians relied on their prefrontal cortex, which is responsible for executive functions like planning complex cognitive behavior and decision-making.

The professional improv comedians let their free associations give them solutions, Biederman said.

To put it another way, The more experience you have doing comedy, the less you need to engage in the top-down control and the more you rely on your spontaneous associations, Amir said.

The researchers also found that funniness ratings were higher for captions created while the participants had higher activity in the temporal regions of their brain during humor creation.

Amir noted that across different studies that seek to understand the neural correlates of creativity in the brain, the medial prefrontal cortex is the one region consistently connected to creativity.

The question is what does it do exactly? It seems like its not the source of creativity, but rather the cognitive control top-down director of the creative process, he said. The creativity itself appears to occur elsewhere depending on the creative task.

In the past, scientists have studied the neural correlates of creativity with tasks such as writing a poem, improvising jazz or drawing a picture, but humor offered Amir and Biederman a unique pathway to study how the brain processes creation.

Humor is an outstanding testbed for studying creativity, Biederman said. It has a clear beginning, middle and end with a duration brief enough for neuroimaging. Also, the end product is easy to evaluate: Does it make you laugh? When someone creates an original composition or a poem, assessing the quality is not as clear-cut.

The study builds on the research from Biedermans Image Understanding Laboratory, which studies the cortical basis of high-level visual recognition. The same temporal lobe regions that show high activation from humor are also activated by the aesthetic experience of appreciating a magnificent vista, for instance.

Biederman noted that the activation, and hence the pleasure, is greatly reduced by the repetition of any experience. The thrill is gone the second time we hear the joke, read the book or see a movie. Thus the pleasure isnt an end in and of itself, but it is what drives us to continually seek new and richly interpretable experiences. This then renders us, as Biederman has termed it, infovores, meaning humans are hardwired to crave new information and experiences.

Biederman holds the Harold Dornsife Chair in Neurosciences at the USC Dornsife College of Letters, Arts and Sciences. Amir is now a postdoctoral researcher at the University of California, Santa Barbara. Their findings were published in Frontiers in Human Neuroscience.

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How being funny changes your brain - USC News

Organovo (ONVO) Publishes Data Describing Physiology of 3D Bioprinted Human Kidney Tissues for Drug Toxicity … – StreetInsider.com

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Organovo Holdings, Inc. (NASDAQ: ONVO) (Organovo), a three-dimensional biology company focused on delivering scientific and medical breakthroughs using its 3D bioprinting technology, today announced the publication of data in Frontiers in Physiology showing the companys 3D bioprinted proximal tubule tissue model exhibits key characteristics of renal physiology that allow for in vitro kidney toxicity testing.

Traditional preclinical models often fall short in their ability to inform clinical outcomes accurately, largely due to the limited functionality of simple in vitro models and species differences, said Dr. Sharon Presnell, chief scientific officer, Organovo. Our newly published data demonstrate that Organovos 3D bioprinted human kidney tissue has great potential to assess the toxic effects of compounds and the development and progression of complex, multicellular processes such as fibrosis.

Key findings and attributes described in the publication include the following:

In addition to the kidney publication, the Company noted a recent article published in ILAR Journal. The publication explores new technologies that could reduce both dependency on animal models and occurrence of liver toxicity in clinical trials. The article, written by scientific executives and experts from the Food & Drug Administration (FDA), Merck & Co., Inc and LifeNet Health, provides a thorough review of human tissue models and how they can accelerate drug development across all discovery stages, including Organovos 3D bioprinted liver model.

The authors reference Organovos technology as a significant innovation in the study of drug-induced liver injury, as it addresses many of the shortcomings associated with traditional in vitro culture models and animal models. They also state that 3D bioprinted tissues exhibit a broad range of highly differentiated in vivo like features and functions.

The authors reference results from Organovos drug-induced liver injury studies that have shown very good reproducibility and concordance with observed outcomes in vivo at the functional and histological levels and that treatment of the bioprinted human liver model with known fibrotic agents mimicked closely that of patient liver samples with drug-induced fibrosis.

Both liver and kidney drug toxicities are significant challenges for pharmaceutical companies working to advance safe and effective therapeutics, said Mr. Keith Murphy, CEO, Organovo. Previous validation data of our 3D bioprinted human liver tissue, combined with the data published in the peer-reviewed journal, Frontiers of Physiology, on our 3D bioprinted kidney proximal tubule tissue, clearly show that Organovos technology can address the unmet needs of our pharma customers and partners by providing timely, cost-effective, and more accurate human tissue models for evaluating drug toxicity and drug-induced fibrotic disease.

Organovos publication titled 3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing, was published online on February 15, 2017 and can be found on the journals website: http://journal.frontiersin.org/article/10.3389/fphys.2017.00123/abstract

The review titled The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development, was published December 31, 2016 and can be found on the journals website: https://academic.oup.com/ilarjournal/article-abstract/57/2/186/2806701/The-Promise-of-New-Technologies-to-Reduce-Refine

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Organovo (ONVO) Publishes Data Describing Physiology of 3D Bioprinted Human Kidney Tissues for Drug Toxicity ... - StreetInsider.com

The physiology of a defeated Shahjahanabad – Livemint

At the end of 1862, the Jama Masjid was handed over to a committee elected by the majority of the Muslim inhabitants, but they were made to sign an agreement which, among other duties, required them to report any use of seditious language. The rules to be enforced in the mosque were also set down by the government, (and) included the clause that European officers and gentlemen civil and military can enter without restriction as to shoes. The Red Fort was now occupied by the army, and lived in by many British officials and their families. Indians could enter only by paying a fee, and were let in to attend the gora bazaars, which were events modelled on the meena bazaars, or womens bazaars, of Mughal times.

The city was slowly rebuilt along new lines. On the northern side of Chandni Chowk, in the place where Jahanaras sarai had stood, the Town Hall was built between 1860-65, out of provincial funds and subscriptions. It was originally known as the Lawrence Institute, after John Lawrence, the Lieutenant Governor of Punjab Province. It housed a chamber of commerce, (a) literary society and museum. In 1866, it was bought over by the municipality and became the Town Hall. The garden north of Chandni Chowk was re-landscaped and renamed Queens Garden. It included a cricket ground, a bandstand, and a menagerie containing various animal species. South of it, in the middle of Chandni Chowk, a clock tower was built. The Mughal-era hammam had been demolished, and where it had stood, was now one end of a new road, officially named Egerton Road, but popularly called Nai Sarak. In the Kotwali Chowk, a new fountain was builtthe phawwara, which in time led to the square being popularly called Phawwara Chowk or fountain chowk. The channel of water that had flowed along the middle of the street was bricked over.

The railways came to Delhi, the first train steaming in on New Years Eve 1867. The railway line was built across the northern half of the city, cutting the city in two. It necessitated the demolition of many houses, the owners of which were compensated with property confiscated after the Revolt. The railways had a positive impact on the trade passing through Delhi. Prosperity increased, at least among the trading class. Between 1868 and 1869, the total tax collected from the bankers, piece goods merchants, grain merchants and traders in food in Delhi district doubled.

That some of the gaiety had returned to the city was noted by a visitor from Calcutta in 1866Bholanath Chander. He visited Shahjahanabad during Diwali, and noted the illumination, and the exhibition of dolls, toys and confectionary and the whole street lighted up by little glass lamps, cherags, and candles. He also remarked that the Mahomedans now fully enjoy the Hindoo festival, though in the mistaken belief that at one time they had not.

While the traders had prospered, the old, mainly Muslim, aristocracy had been impoverished. Many were reduced to manual work, or poorly paid jobs as schoolteachers. Many of them, along with the other poorer population, lived on the fringes of the city along the city wallsMori Gate, Ajmeri Gate, Turkman Gate, Delhi Gate and Khidki Farrashkhana. Former noblewomen were reduced to spinning gota for a subsistence. Famines in the 1860s further compounded the problem by pushing up food prices.

After the revolt, the city had been placed under martial law. In 1861, it came back to civil administration, but under the Punjab Province rather than the North-Western Provinces, to which it had earlier belonged. The municipality, inaugurated in 1863, became an important agency for the civil management of the city. Not surprisingly, the municipal commissioners were mostly members of the mercantile eliteprominent Hindu and Jain merchants, who had supported the British cause during the Revolt. Among the few Muslim members of the municipality was Mirza Illahi Baksh, a member of the royal family, who had covertly helped the British during 1857, and his son. The municipal council was essentially a conservative body with a limited role; through the 1860s, 75 per cent of municipal expenditure was spent on the police.

...

The 1860s-70s was a time when a number of schools, including girls schools, were opened with the efforts of both Hindus and Muslims. The Anglo-Arabic School was set up in 1872, and was housed in Ghaziuddin Madrasa from 1889. The Anglo-Sanskrit School was established in 1869, in a haveli donated by Lala Chunna Mal near Katra Neel in Chandni Chowk and financed by him. The Delhi College had been reduced to the status of a high school after the revolt, which it remained till 1864, when college level classes were started. The college, though it had not recovered from the damage done to its library and laboratories during 1857, still enjoyed a good reputation. It therefore came as a shock when, in 1877, the government announced that the college classes would be shifted to Lahore College.

"An indirect effect of the Durbar was that it drew to Delhi people who would have a long-term effect on the city."-

Ironically this announcement was made in the wake of the Imperial Assemblage, or Durbar of 1877, held in Delhi, by which it was hoped to show the British sovereigns interest in this great Dependency of Her Crown, and Her Royal confidence in the loyalty and affection of the Princes and People of India.

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For the people of Shahjahanabad, the Durbar had limited meaning. The Durbar site was well outside the city walls. Even during the Viceroys one procession through the city, the streets were lined with soldiers, who effectively insulated the cavalcade from the people. As a concession to the people of Delhi, two mosques, the Zinat-ul-Masajid and the Fatehpuri Masjid, which had been confiscated after the revolt, were reopened for worship. An indirect effect of the Durbar was that it drew to Delhi people who would have a long-term effect on the city. Dayanand Saraswati, the founder of the Hindu reform movement, the Arya Samaj, visited Delhi for the Durbar. As a direct outcome of the visit, a branch of the Samaj was formed here the following year. Around the same time, a branch of the Theosophical Society, a neo-Hindu movement, too, was established.

From the second half of the 1870s, there began a phase of increased sectarian activity and conflict. Active proselytization, based on public preaching at bazaars by Christian missionaries, had been going on since soon after the Revolt. Soon, there was a mushrooming of sectarian organizations. Apart from the new movements such as the Theosophical Society and the Arya Samaj, orthodox Hinduism was represented by the establishment of the headquarters of the Bharat Dharam Mahamandal, and the Sanatan Dharam Sabha in the 1890s.

There was also a host of purely local Hindu bodies that sprang up in the 1880s and 90s, many of which were caste-based. In 1878 a Jain Sabha was set up in Dharampura locality, adjoining Dariba, presumably as a response to the Arya Samaj. Among the Muslims, the Anjuman-e-Islamia, founded in 1875, performed the role of promoting the interests of Muslims.

The negative side of the increasing assertion of religious identity were sectarian riots. These conflicts afflicted the city on several occasions during the 1880s and 90s, and centred around issues such as cow-protection and rival religious processions. The latter included conflict between Jains and Hindus. The issue of proselytization and conversion also caused conflict between Christian missionaries, Muslims, Arya Samajis and Sanatan Hindus.

The constructive outcome of these sectarian movements was the founding of educational institutions. Two among these stand out in particular. St Stephens College was founded in 1881 by the Cambridge Mission. With humble beginnings in a haveli just off Kinari Bazaar, it soon got a new building near Kashmiri Gate. In 1899, Hindu College was established to provide an education on Sanatanist Hindu lines. The college received financial backing from Kishen Das Gurwala, and was set up in Kinari Bazaar. Then Lala Sultan Singh sold some property in Kashmiri Gate to the college, and it came to occupy a spot just across the road from St Stephens.

Despite religious disputes that cropped up from time to time, the people of Delhi were able to overcome their differences in times of greater trouble. The famine of 1898-1900 and the subsequent plague scare brought various communities together, and this solidarity was expressed by Hindus greeting Muslims emerging from the Jama Masjid after Eid, members of the two communities accepting water from each other, and Muslims participating in Holi celebrations.

This is an edited excerpt from the chapter The Revolt And Its Aftermath in Swapna Liddles book Chandni Chowk: The Mughal City Of Old Delhi.

*****

Swapna Liddles Old Delhi secrets

A haveli that hosted Nehrus baraat and the mosque Shah Jahans wife built

Kucha Pati Ram: In a city that has become increasingly commercial in its land use, it is refreshing to see some streets that are still predominantly residential. The houses of this neighbourhood, just off Hauz Qazi, are beautiful, some with richly carved traditional doorways and balconies, others with equally rare though not so old, Art Deco-inspired doorways in terrazzo. In nearby Gali Prem Narayan is the ruined Haksar haveli where the Nehru baraat stayed during the wedding of Jawaharlal and Kamala Nehru.

Fatehpuri Masjid: Few visitors go to Fatehpuri Masjid, commissioned by Fatehpuri begum, one of the wives of Mughal emperor Shah Jahan. After the revolt, it remained closed for 20 years. It was restored for worship in 1877, as a boon of the Delhi Durbar. The spacious courtyard does not have the impo-sing grandeur of the Jama Masjid, but is in a more human, intimate scale. Stepping into it from the bustle of the bazaar outside, one is suddenly in an oasis of peace. The attached public library is an added attraction for those wanting to research the history of the city and more.

First Published: Fri, Feb 17 2017. 02 27 PM IST

Read more:
The physiology of a defeated Shahjahanabad - Livemint

Human Anatomy Coloring Study Muscular System Physiology Learning Book Launched – MENAFN.COM

(MENAFN Editorial) A new human body coloring book has launched, aimed at those in the medical field or working with the human body on a professional or educational basis. Students who have to take anatomy and physiology tests will know that the muscular system is one of the most difficult sections to learn, and it's because of this that the new coloring book has been launched.

More information can be found at: https://youtube.com/watch?v=5Wr32A1oJB0.

One of the things that makes the anatomy and physiology test so hard is that people have to learn the location and names of between 640 to 850 muscles in the human body. Using the new coloring book, customers can master the muscular and benefit from realistic medical anatomy.

The realism behind the drawings in the book can help the reader to master the muscular system while they are enjoying coloring the different detailed sections of the human body. Once the drawings have been colored in, they can then be compared with the labeled version, which is also available to color.

This meansthat people using the coloring book can learn the human anatomy and physiology of the body while coloring to boost their knowledge and gain a better understanding of the muscular system.

Because each customer will spend a while on each section of the human body, the repetitive and methodical nature of coloring in the book helps to promote learning and allow the names and muscles to stick in the mind.

Coloring will improve the study ability of each customer, as well as helping to improve reference recall by fixating the anatomical images in their mind for easy visual recall later on simply through coloring the body parts in the book.

Through coloring the book, customers can imprint the different shapes and the location of each muscle on their mind, helping them to recall them later on when they need to. This interactive approach means people don't have to spend hours memorizing muscles on their own.

Full details can be found by visiting the URL above.

MENAFN2002201700703206ID1095256480

Continued here:
Human Anatomy Coloring Study Muscular System Physiology Learning Book Launched - MENAFN.COM

Unwrapping the Physiology of a Tour de France Champion – Newswise (press release)

Newswise Given the current spotlight on sport concerning the use and abuse of Performance Enhancing Drugs (PEDs), there is a public interest in athletes providing greater transparency with regard to what makes them elite. In this study, the investigators conducted a thorough examination into the physiological characteristics of a two-time Tour de France champion cyclist. Several interesting results were found including: 1) some of the highest aerobic capacity values in a cyclist on record; 2) high cycling efficiency; and 3) a higher than anticipated body fat percentage. Collectively, the data demonstrated what may be the required physiological characteristics to be a Tour de France champion. While the data can neither confirm nor deny the use of PEDs, it is perhaps a step in the right direction to publicly demonstrate the type of physiology required to be one of the greatest endurance athletes in the world. For more information, view the abstract or contact the investigator.

Read the rest here:
Unwrapping the Physiology of a Tour de France Champion - Newswise (press release)

Human Anatomy Coloring Study Muscular System Physiology Learning Book Launched – Satellite PR News (press release)

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Students, scientists and people working on the human body can now memorize muscle location and names through a new coloring book. The book helps to build a better understanding of muscle location and the human anatomy.

Colorado Springs, United States February 14, 2017

A new human body coloring book has launched, aimed at those in the medical field or working with the human body on a professional or educational basis. Students who have to take anatomy and physiology tests will know that the muscular system is one of the most difficult sections to learn, and its because of this that the new coloring book has been launched.

More information can be found at: https://youtube.com/watch?v=5Wr32A1oJB0.

One of the things that makes the anatomy and physiology test so hard is that people have to learn the location and names of between 640 to 850 muscles in the human body. Using the new coloring book, customers can master the muscular and benefit from realistic medical anatomy.

The realism behind the drawings in the book can help the reader to master the muscular system while they are enjoying coloring the different detailed sections of the human body. Once the drawings have been colored in, they can then be compared with the labeled version, which is also available to color.

This means that people using the coloring book can learn the human anatomy and physiology of the body while coloring to boost their knowledge and gain a better understanding of the muscular system.

Because each customer will spend a while on each section of the human body, the repetitive and methodical nature of coloring in the book helps to promote learning and allow the names and muscles to stick in the mind.

Coloring will improve the study ability of each customer, as well as helping to improve reference recall by fixating the anatomical images in their mind for easy visual recall later on simply through coloring the body parts in the book.

Through coloring the book, customers can imprint the different shapes and the location of each muscle on their mind, helping them to recall them later on when they need to. This interactive approach means people dont have to spend hours memorizing muscles on their own.

Full details can be found by visiting the URL above.

Contact Info: Name: Lloyd Organization: Human Body Coloring Books Address: 7518 Banner Court, Colorado Springs, CO 80920, United States

For more information, please visit https://www.youtube.com/watch?v=5Wr32A1oJB0

Source: PressCable

Release ID: 169642

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Human Anatomy Coloring Study Muscular System Physiology Learning Book Launched - Satellite PR News (press release)