Nobel Prize in Physiology or Medicine awarded to 2 discoverers of microRNA Fierce Biotech
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Nobel Prize in Physiology or Medicine awarded to 2 discoverers of microRNA - Fierce Biotech
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Victor Ambros and Gary Ruvkun Win the Nobel Prize in Physiology or Medicine 2024 – Technology Networks
Johns Hopkins University vs. Stanford University: Which University Dominates in Anatomy & Physiology? – The Times of India
Master of Science in Medical Physiology virtual information session – The Daily | Case Western Reserve University
Master of Science in Medical Physiology virtual information session The Daily | Case Western Reserve University
Stop saying lactic acid causes fatigue! says physiology expert in response to Games in Paris – Loughborough University
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Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking … – Nature.com
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Pharmacology and Physiology Faculty Awarded Grants Totaling $1.5 million – Saint Louis University
Daniela Salvemini, Ph.D., William Beaumont Professor, chair of the Department of Pharmacology and Physiology, and director of the Institute of Translational Neuroscience, in collaboration with Stephanie Geisler M.D., Ph.D., assistant professor of neurology at Washington University in St. Louis, have been awarded an ICTS/CTRFP grant award of $50,000. The grant Sphingolipidomics to identify small fiber neuropathy endotypes will examine whether sphingolipids can be used as biomarkers to identify subgroups of patients with small fiber neuropathy, which may lead to the development of personalized, targeted therapies. There currently are no effective treatments for small fiber neuropathy.
Andrew Butler, Ph.D., a professor of pharmacology and physiology, was awarded a two-year $416,625 grant by the National Institute of Aging titled "Methods for treating aging-related cognitive decline and reducing risk of AD/ADRD by enhancing the endogenous expression of adropin" (R21 AG087308). The investigators of this award recently reported community-dwelling adults with low levels of the secreted peptide adropin have increased risk of cognitive decline. Working with Andrew Nguyen, Ph.D., assistant professor of pharmacology and physiology, this funding will identify methods that induce long-term increases in the expression of the endogenous adropin protein. The long-term objective of this project is to determine whether three to six monthly injections of a long-acting drug are effective at preserving cognition in aging. Other members of the team include Susan Farr, Ph.D., professor of internal medicine; Geetika Aggarwal, Ph.D., staff research scientist; and Denise Smith, senior research assistant.
Butler was also awarded a two-year $416,625 grant by the National Institute of Aging titled "An investigation of the response of preclinical mouse models of dementia to adropin therapy" (R21 AG083451). Aging increases risk for cognitive decline due to neurodegenerative diseases, of which Alzheimers disease is most common. Working with Farr, the goals of this award are to test the efficacy of a small, soluble peptide in protecting the brain and cognitive functions in a mouse model of accelerated aging. The award will also determine whether loss of the peptide accelerates aging-related cognitive decline. This work will define the pathways through which this peptide preserves brain function in aging and could lead to a new therapy for treating Alzheimers disease. Other members of the team include Aggarwal and Aubin Moutal, Ph.D., assistant professor of pharmacology and physiology.
Gina Yosten, Ph.D., an associate professor of pharmacology and physiology, was awarded an 18-month $162,000 grant from the Foundation of Prader Willi Research titled Spatial Molecular Imaging of the Human PWS Hypothalamus (1243623). Working with Grant Kolar, Ph.D., professor of pathology and pharmacology and physiology, this funding will allow for the investigation of spatial molecular profiles of cells of the hypothalamus using tissues from donors with Prader Willi syndrome and matched control donors. The long-term objective of this study is to evaluate how spatially-driven interactions between the different cell types within the hypothalamus might contribute to the pathogenesis and symptomology of Prader Willi syndrome. Ms. Megan Pater, a graduate student in Pharmacology and Physiology, and an expert in spatial molecular imaging, will play an instrumental role in this study.
Yosten was also awarded a one-year $60,156 grant from the Foundation of Prader Willi Research titled Evaluate Ultrastructure of Hypothalamic Tissues from Mouse and Rat Models of PWS and Human PWS Donors (1314260). Working with Kolar, this project will investigate how deficiency of the MAGEL2 gene, which exhibits impaired expression in the setting of Prader Willi syndrome, impacts secretory granule structure and function. The long term objective of this study is to determine whether impairments in secretory granule trafficking underly the phenotypes associated with Prader Willi syndrome and other syndromes with MAGEL2 deficiency.
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Pharmacology and Physiology Faculty Awarded Grants Totaling $1.5 million - Saint Louis University
ESAFE – Postdoctoral Position in Molecular Plant Physiology job with MOHAMMED VI POLYTECHNIC UNIVERSITY … – Times Higher Education
Understanding the molecular mechanisms that control the mineral homeostasis/status of plants and their responses to major abiotic constraints.
About UM6P:
Mohammed VI Polytechnic University is an institution dedicated to research and innovation in Africa and aims to position itself among world-renowned universities in its fields The University is engaged in economic and human development and puts research and innovation at the forefront of African development. A mechanism that enables it to consolidate Moroccos frontline position in these fields, in a unique partnership-based approach and boosting skills training relevant for the future of Africa. Located in the municipality of Benguerir, in the very heart of the Green City, Mohammed VI Polytechnic University aspires to leave its mark nationally, continentally, and globally.
Job Summary:
The postdoc will conduct research, prepare proposals, write reports and scientific papers to address how plants react and adapt to water, salt, nutrient and metal stresses which alter the acquisition and usage of water and mineral nutrients (potassium, nitrogen, phosphorus, micronutrients) and which can affect crop productivity. The candidate will conduct research activities tacklingthe mechanisms that allow plants to perceive abiotic environmental constraints (such as water/ nutrient availability) and therefore modulate their development or their physiology (photosynthesis, root uptake, utilization, and storage of water/nutrients). The candidate will conduct research activities tackling all aspects related to crop production testing and developing solutions and best practices to improve agricultural productivity under marginal and arid conditions.
The candidate should have a PhD in Plant Biology, preferentially with a focus on bio-chemical methods and molecular biology. The ideal candidate should have a strong motivation and passion to science, a fundamental knowledge in plant molecular physiology/ cell biology. The candidate should have extensive laboratory experience with bio-chemical methods and plant molecular physiology/ cell biology. The ability to be independent as well as cooperate in a team, are required.
The application should contain:
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ESAFE - Postdoctoral Position in Molecular Plant Physiology job with MOHAMMED VI POLYTECHNIC UNIVERSITY ... - Times Higher Education
Why psychology is as important as physiology for plastic surgery – The Times
Most of us have a hard enough time trying to understand how cosmetic surgery works so the question of why people do it can be even more baffling. Aesthetic tweakments are more popular than ever, but many question the necessity of them.
What isnt widely understood is that turning to the needle or knife is often less about vanity and more about identity.
In fact, the man credited with inventing cosmetic surgery did so with psychology in mind. The surgeon Sir Harold Gillies developed his methods of facial reconstruction during the First World War when dealing with soldiers life-changing injuries. He focused not only on repairing the functionality of the face but on the aesthetic details too, believing that the psychological impact of how they would look could be as affecting as the physical injuries. Ida Banek, a trained psychologist and the founder of Ouronyx, an aesthetic clinic in London that focuses on facial procedures, believes that understanding this link is a key component of treating clients.
As part of her consultation process, patients have to have a strong and deep conversation about their personality type, to clarify their objectives, how they see themselves and how they wish to see themselves. The vast majority, she says, have goals that are based on confidence and emotions, rather than looking different or younger.
Turning to aesthetic treatments or surgery can be a way to restore confidence, although the link between the procedure and the emotional result isnt always linear, says the psychotherapist Emma Reed Turrell. Confidence is less about appearance and more about self-consciousness, she says. We know that there is strong correlation between self-consciousness and unhappiness: its not so much about how we look, its how we feel about the way we look. Rather cruelly, though, negative feelings about our looks cant always be attributed only to low self-esteem they can be psychologically hard-wired.
Our brain leads us to see ourselves differently from how we see others, and analyses our own image in high-definition detail, says Rajiv Grover, a consultant plastic surgeon and former president of the British Association of Aesthetic Plastic Surgeons. But our perception of others is similar to that of an impressionist artist [appreciating the form as a whole]. This means we look at ourselves with a more critical eye.
However, out of about 1,000 clients questioned at Ouronyx, 95 per cent in all but one age group said they wanted to look fresher and well rested. It was only among the under-30s that clients wanted to look more striking, feminine or masculine. They want to change their appearance rather than optimise it, Banek says, which is one of the reasons were very cautious with that particular group. Three quarters of those in their twenties have been turned away, she adds; what the clinic doesnt want to promote is a fast-beauty culture, which has the potential to encourage young people [to have] premature and possibly unnecessary cosmetic interventions.
Sadly not all clinics adhere to these principles, and regulation within the industry is weak. Im clearly biased, but I would love everyone to have access to a therapist or psychologist whenever they are making major decisions in life, such as cosmetic surgery, Reed Turrell says. Although, of course, its difficult to draw a line: would a millilitre or two of filler be considered a major life decision? It cant hurt to understand your motivations more clearly, she says, so you can feel grounded and confident, however you choose to move forwards.
Though its now widely accepted that the aesthetics route is one people should be able to take freely and safely, there is often the risk of someone altering their appearance beyond what would be considered natural-looking, or becoming addicted to procedures. Sometimes this is because of body dysmorphia, a diagnosable medical condition that requires treatment outside an aesthetic clinic. In other cases, Banek says, its simply human nature. We tend to forget the past relatively fast and focus on what we see in the mirror in the moment. You forget what the starting point was.
Before-and-after photos can help to remind patients of their journey, as well as to manage their expectations so they dont face disappointment or try something else. Ive worked with people who find themselves disillusioned and sometimes physically and financially damaged by procedures that could never fix the problem, Reed Turrell says, because it wasnt simply one of appearance, it was one of self-worth.
This is why industry leaders including Banek and Grover are passionate about making sure that patients seriously contemplate the risks and consider psychological guidance. In the meantime, Banek says, the best we can do is to ensure regulation becomes stronger. Education around the psychological reasons for and impact of aesthetic decisions, especially for younger people, is paramount.
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Why psychology is as important as physiology for plastic surgery - The Times