Category Archives: Physiology

Physiology

Global Preclinical Software for Physiology Data Assessment and Animal Supervision Market (2020 to 2024) – Featuring Thermo Fisher Scientific, TSE…

The "Global Preclinical Software for Physiology Data Assessment and Animal Supervision Market 2020-2024" report has been added to ResearchAndMarkets.com's offering.

The preclinical software for physiology data assessment and animal supervision market is poised to grow by $ 2.97 million during 2020-2024 progressing at a CAGR of 5% during the forecast period.

The report on preclinical software for physiology data assessment and animal supervision market provides a holistic analysis, market size and forecast, trends, growth drivers, and challenges, as well as vendor analysis covering around 25 vendors.

The report offers an up-to-date analysis regarding the current global market scenario, latest trends and drivers, and the overall market environment. The market is driven by the emerging roles of bioinformatics tools and software, importance of physiological monitoring in preclinical research, and increasing use of animals in preclinical studies.

The preclinical software for physiology data assessment and animal supervision market analysis includes end-user segment and geographical landscapes. This study identifies the rising digitalization in preclinical research as one of the prime reasons driving the preclinical software for physiology data assessment and animal supervision market growth during the next few years. Also, increasing outsourcing of preclinical research, and increased demand for SEND submission software for preclinical data will lead to sizable demand in the market.

The report presents a detailed picture of the market by the way of study, synthesis, and summation of data from multiple sources by an analysis of key parameters.

Companies Mentioned

The preclinical software for physiology data assessment and animal supervision market covers the following areas:

The study was conducted using an objective combination of primary and secondary information including inputs from key participants in the industry. The report contains a comprehensive market and vendor landscape in addition to an analysis of the key vendors.

The report presents a detailed picture of the market by the way of study, synthesis, and summation of data from multiple sources by an analysis of key parameters such as profit, pricing, competition, and promotions. It presents various market facets by identifying the key industry influences. The data presented is comprehensive, reliable, and a result of extensive research - both primary and secondary.

This market research report provides a complete competitive landscape and an in-depth vendor selection methodology and analysis using qualitative and quantitative research to forecast an accurate market growth.

Key Topics Covered:

1. Executive Summary

2. Market Landscape

3. Market Sizing

4. Five Forces Analysis

5. Market Segmentation by End-user

6. Customer Landscape

7. Geographic Landscape

8. Vendor Landscape

9. Vendor Analysis

10. Appendix

For more information about this report visit https://www.researchandmarkets.com/r/937rho

View source version on businesswire.com: https://www.businesswire.com/news/home/20201021005487/en/

Contacts

ResearchAndMarkets.comLaura Wood, Senior Press Managerpress@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470For U.S./CAN Toll Free Call 1-800-526-8630For GMT Office Hours Call +353-1-416-8900

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Global Preclinical Software for Physiology Data Assessment and Animal Supervision Market (2020 to 2024) - Featuring Thermo Fisher Scientific, TSE...

Physiology

Intermittent Fasting Re-Examined – New Research by Lumen Suggests Over-Fasting May Result in Potential Weight Gain – PRNewswire

NEW YORK, Oct. 22, 2020 /PRNewswire/ --Lumen, a health tech company at the forefront of metabolic tracking, has uncovered data that changes industry assumptions on intermittent fasting.

Lumen is the world's first handheld metabolism tracker, which works by measuring your body's carbon dioxide concentration in just one breath. By using Lumen, you can understand if you're burning fats or carbs for fuel on a daily basis.

According to polls, 24% of US adults have tried intermittent fasting for weight loss, but Lumen data engineers are now seeing that an overwhelming number of their users are experiencing what they call a stress response to fasting too many hours.

"People can reach great results by using fasting as a tool for weight loss and achieving a healthy metabolism, however, optimizing your fasting routine is crucial since each one of us has a different metabolism. Therefore, some will need longer fasting windows than others in order to optimize the result of their fast," says Barak Alon, Head of Data at Lumen.

With over 1 million monthly metabolism measurements made by Lumen users, the Lumen data team found insights to help users optimize their fasting and avoid a counteractive stress response.

While the ideal is to be in a constant fat burning state during a fast, over 27% of Lumen users that fasted more than 10 hours experienced a carb burn state even though their morning measurements indicated they were burning fat, which can be described as a stress response.

This happens when your body has overextended its fat burning state and the opposite result is triggered, as carbs are used rather than fat as fuel.

However, the data still supports the benefits of intermittent fasting. According to data experts at Lumen, users that fasted progressively in an optimized and measured framework were able to successfully achieve fat burn.

Lumen encourages intermittent fasting, but with a personalised and optimized approach that keeps metabolic health in mind. Extreme hunger pangs, restlessness, and agitation are physiological indicators of a stress response. Therefore, taking a post-fast metabolic measurement is a recommended solution to avoid cancelling the many benefits of fasting. Just by creating more awareness of physiological symptoms, intermittent fasters can safely optimize their fat burn.

About LumenLumen helps people improve their health and fitness through technology on the forefront of personalized nutrition and metabolism. Conceived and designed by twin sisters, physiology PhDs and Ironman winners, Lumen harnesses the power of our breath to measure metabolism, which is closely linked to weight, fitness and metabolic health. The Lumen device measures metabolism in a single breath, in less than a minute, which previously was only possible through an hour-long lab test. Available at Lumen.me, Lumen devices ship globally, with the app available on the Apple App Store and Google Play. Lumen is headquartered in Israel, with offices in the United States.

Contact:Kyla Blumenfeld+972548161939[emailprotected]

SOURCE Lumen

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Intermittent Fasting Re-Examined - New Research by Lumen Suggests Over-Fasting May Result in Potential Weight Gain - PRNewswire

Physiology

Best way to detect deepfake videos? Check for the pulse – Binghamton University

By Chris Kocher

October 21, 2020

With video editing software becoming increasingly sophisticated, its sometimes difficult to believe our own eyes. Did that actor really appear in that movie? Did that politician really say that offensive thing?

Some so-called deepfakes are harmless fun, but others are made with a more sinister purpose. But how do we know when a video has been manipulated?

Researchers from Binghamton Universitys Thomas J. Watson College of Engineering and Applied Science have teamed up with Intel Corp. to develop a tool called FakeCatcher, which boasts an accuracy rate above 90%.

Lijun Yin is a professor in Watson Colleges Department of Computer Science. Image Credit: Jonathan Cohen.

FakeCatcher works by analyzing the subtle differences in skin color caused by the human heartbeat. Photoplethysmography (abbreviated as PPG) is the same technique used for a pulse oximeter put on the tip of your finger at a doctors office, as well as Apple Watches and wearable fitness tracking devices that measure your heartbeat during exercise.

We extract several PPG signals from different parts of the face and look at the spatial and temporal consistency of those signals, said Ilke Demir, a senior research scientist at Intel. In deepfakes, there is no consistency for heartbeats and there is no pulse information. For real videos, the blood flow in someones left cheek and right cheek to oversimplify it agree that they have the same pulse.

Working with Demir on the project is Umur A. Ciftci, a PhD student at Watson Colleges Department of Computer Science, under Professor Lijun Yins supervision at the Graphics and Image Computing Laboratory, part of the Seymour Kunis Media Core funded by donor Gary Kunis 73, LHD 02 It builds on Yins 15 years of work creating multiple 3D databases of human faces and emotional expressions. Hollywood filmmakers, video game creators and others have utilized the databases for their creative projects.

At Yins lab in the Innovative Technologies Complex, Ciftci has helped to build what may be the most advanced physiological capture setup setup in the United States, with its 18 cameras as well as in infrared. A device also is strapped around a subjects chest that monitors breathing and heartrate. So much data is acquired in a 30-minute session that it requires 12 hours of computer processing to render it.

Umur has done a lot of physiology data analysis, and signal processing research started with our first multimodal database, Yin said. We capture data not just with 2D and 3D visible images but also thermal cameras and physiology sensors. The idea of using the physiology as another signature to see if it is consistent with previous data is very helpful for detection.

Umur Ciftci, a PhD student in computer science, poses for a 3D scan in Professor Lijun Yins lab at the Innovative Technologies Complex. Ciftcis doctoral thesis will focus on detecting deepfake videos. Image Credit: Jonathan Cohen.

Deepfakes found in the wild are many steps below the kind of quality that Yins lab generates, but it means that manipulated videos can be much easier to spot.

Considering that we work with 3D using our own capture setup, we generate some of our own composites, which are basically fake videos, Ciftci said. The big difference is that we scan real people and use it, while deepfakes take data from other people and use it. Its not that different if you think about it that way.

Its like the police knowing what all the criminals do and how they do it. You understand how these deepfakes are being done. We learn the tricks and even use some of them in our own data creation.

Since the FakeCatcher findings were published, 27 researchers around the world have been using the algorithm and the dataset in their own analyses. Whenever these kinds of studies are made public, though, there are concerns about telling malicious deepfake makers how their videos have been shown to be false, allowing them to modify their work to be undetectable in the future.

Ciftci is not too worried about that, however: Its not going to be easy for someone who doesnt know much about the science behind it. They cant just use whats out there to make this happen without significant software changes.

Intels involvement in the FakeCatcher research is connected to its interests in volumetric capture and augmented/virtual reality experiences. Intel Studios operates what Demir calls the worlds largest volumetric capture stage: 100 cameras in a 10,000-square-foot geodesic dome that can handle about 30 people simultaneously even a few horses once.

Future plans include volumetric-capture technology to be included in mainstream television shows, sports and augmented-reality applications, where the audience can immerse in any scene. Films in 3D and VR also are in the works, with two VR projects recently premiering at the Venice Film Festival.

By compiling the FakeCatcher data and reverse-engineering it, Intel Studios hopes to make more realistic renderings that incorporate the kind of biological markers that humans with real heartbeats have.

Intels vision is changing from a chip-first company to putting AI, edge computing and data first, Demir said. We are making a transformation to AI-specific approaches in any way we can.

(Interesting to note: Intels CEO is Bob Swan, MBA 85, who last year told the School of Management magazine Reaching Higher that intellectual curiosity is a wonderful and powerful thing to help you grow and develop and evolve over time.)

Future research will seek to improve and refine the FakeCatcher technology, drilling further down into the data to determine how the deepfakes are made. That capability has many implications, including cybersecurity and telemedicine, and Yin also hopes for further collaborations with Intel.

Were still in the brainstorming stage, he said. We want to have an impact not only in academia but also to see if our research would have a role in industry.

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Best way to detect deepfake videos? Check for the pulse - Binghamton University

Physiology

FDA invites comment on nutrition labeling of sugars that are metabolized differently than traditional sugars – FoodNavigator-USA.com

In a request for comment, the agency notes that, Some sugars (e.g., allulose, D-tagatose, isomaltulose) do not have all of the same effects in the body as traditional sugars.

"Because of that, we have received multiple requests from industry to treat these sugars that are metabolized differently than traditional sugars as distinct from traditional sugars for purposes of nutrition labeling.

We are interested in learning more about the kinds of sugars that are metabolized differently than traditional sugars and that are used in foods, any distinct physiological effects in the body caused by those sugars, and how we should treat those sugars for purposes of food labeling."

Factors that might be relevant include the pH of dental plaque after consumption, caloric value, and glycemic and insulinemic response, adds the agency.

Anke Sentko is VP regulatory affairs & nutrition communication at BENEO, which makes isomaltulose (which it sells under the brand name Palatinose).

A disaccharide manufactured by the enzymatic rearrangement of sucrose from beets, Palatinose has 4 calories per gram like regular sugar, but does not have the same impact on insulin and blood sugar, so has a lower glycemic index and is digested more slowly.

Welcoming the FDA's request for comments, Sentko told FoodNavigator-USA: "Due to todays public health policy direction, all mono- and disaccharides (sugars) are regarded as 'bad for you' and thus should be reduced and replaced. All oligo- and polysaccharides are regarded as good for human nutrition.This classification based on food chemistry is not justified as not all sugars are the same in their physiological effects, and it is physiology that counts if health should be supported...

She added: "Its the physiological carbohydrate quality that matters. A carbohydrate that is available to the body and is digested slowly, leading to a low blood glucose response and low insulin response and allows for fat oxidation in energy management is a carbohydrate of good physiological quality, no matter if it is a monosaccharide, disaccharide, oligosaccharide or polysaccharide.

"If on top it is not used as substrate by oral microorganisms, confirmed by an FDA approved health claim, this sugar has a quality bonus on top. BENEO is addressing its disaccharide isomaltulose here.

"In a food labelling system that singles out sugars from total carbohydrates and stipulates sugars as bad, those sugars that are not bad need to be excluded from the 'total sugars' and 'added sugars' definition and counted as neutral carbohydrates."

Read more HERE. Stakeholders have 60 days to provide comments.

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FDA invites comment on nutrition labeling of sugars that are metabolized differently than traditional sugars - FoodNavigator-USA.com

Physiology

The lens of fear: partnering with families – Guest columns – McKnight’s Long Term Care News

I remember sitting with her, holding her hand, telling her the same information over and over again. Finally, she lifted her head and said, I hear what you are saying. Within five minutes, she asked me the same question again.

You would assume the scene I am describing is one of tragedy. It is not. It is about an interaction in a health care setting and it is about the ability of a human being to hear and process information when stressed.

Fight or flight, or the acute stress syndrome, is a common happening when a human being perceives a threat. I am sure to my Anatomy and Physiology professors dismay the following would make them cringe. I like to envision little people running around pulling the levers to activate the systems of moving blood to our muscles, away from the brain. With the chemical reaction within the body the brains functionality becomes limited. Some researchers have shown that this physiological state gives human beings in essence the brain of a lizard. That is right: When we are stressed, we think with the brain of a lizard. Learn from me, your significant other does not appreciate you pointing out that they have a lizard brain during a spirited discussion.

Having consciousness that the acute stress syndrome reaction is an influencer when talking with families is the first step in awareness of the filters that families might be hearing the information you are trying to share with them. The second filter is fear. You could argue that fear causes the reaction of fight or flight and you would be correct. Fear is the trigger; the reaction is what you must deal with first.

In a familys mind are a million whirling thoughts when they are concerned about the one they love. They are looking for clues that will either support their fears, or alleviate them. It really is that simple.

The game-changer

Early in my career, when I would meet with families, I was professional and factual. I would give them the clear clinical picture and what the team thought would be the course direction with always the qualifier of potentials. I was puzzled that they would not remember what I said, except for the parts that supported their fears. One burly rancher put it into perspective for me one day. He said, Why dont you ask me what I am worried about instead of telling me what you think I need to know?

From that day forward, I changed how I spoke with families. I now work on how to be present to them, actively listening instead of actively talking. I put aside my phone, pager or other device so I am able to be all theirs for the moment. I take deep breaths to clear my lizard mind from the day. I remind myself of their loved ones story. If I do not know it, I ask them to tell me about their loved one. Knowing the story opens up the ability to be empathetic. Furthermore, talking about the loved one brings a centering and grounding that creates a mutual connection. It sets the stage to ask the most important question that can be asked, Tell me what you want to know first. What are you worried about?

Tell me what you want to know first? What are you worried about ? Most families will let out their breath and a flood of thoughts, worries and questions flow out. Some families will ask, what are you worried about? I have learned when they ask that of the provider, they are looking for validation of their worries. I usually say something like, most likely the same things you are thinking about. Lets talk about them together.

I then answer them as openly and with transparency of the information or knowledge that I know as of this moment. What I have learned is that in the absence of asking the question of what they are worried about, the worries grow larger and the fear becomes stronger. That then triggers further the acute stress syndrome, or the fight or flight reaction.

In follow-up conversations I have with families, I bring the questions back around early on in the conversation: 1. Tell me what you want to know. 2. What are you worrying about for your loved one? By discussing together, the worries or fear, it allows a partnership to develop and dialogue on the best course of care with everyone working together for their loved one.

I recently experienced being on the family side. I was the designated care support for my elderly father as only one family member could be present due to COVID restrictions. I was isolated and alone. My stress level was over the top. One provider brought me off the ledge by asking, What are you worrying about for your father? I took a breath and said everything. He laughed and then we talked together about everything.

We are, as one recent political figure said, in the halftime of COVID. People are tired, frustrated and wanting this pandemic to be over. Add to that the restrictions for prevention and containment that have been put into place potentially fosters worries to become stronger and turn into fears. Healthcare, and especially long-term care, have been working hard to communicate in new ways with those they serve and support.

Yet, I find the question, What are you worrying about for your loved one? remarkably absent in conversations. Many conflicts, family dissatisfaction and difficult issues can be worked through by open dialogue and authentic answers. We must use courageous leadership and be willing to ask the question repeatedly to assure we are listening with both head and heart to those we serve. It is going to be critical as we face COVID, part two, during these coming months.

Martie L. Moore, MAOM, RN, CPHQ, has been an executive healthcare leader for more than 20 years. She has served on advisory boards for the National Pressure Ulcer Advisory Panel and the American Nurses Association, and she currently serves on the Deans Advisory Board at the University of Central Florida College of Nursing and Sigma. She recently was honored by Saints Martins University with an honorary doctorate degree for her service and accomplishments in advancing healthcare.

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The lens of fear: partnering with families - Guest columns - McKnight's Long Term Care News

Physiology

Study outlines the link between tattoos and damage to sweat glands – News-Medical.Net

Reviewed by Emily Henderson, B.Sc.Oct 21 2020

You've heard that they can sag with age, perpetuate the name of a regrettable ex, or reveal an embarrassing inability to spell. But tattoos may also impair the way we sweat, potentially causing the body to overheat if the tattoos cover a large area of the body.

A team of researchers that includes SMU physiologist Scott L. Davis outlined the connection between tattoos and damage to sweat glands in a study published in the Journal of Applied Physiology. Their study of tattooed skin and adjacent non-tattooed skin on the arms of an evenly-divided group of men and women found that the tattooed sections of skin had reduced sweat rates.

That's a potential problem because sweating is how the body cools itself and regulates its temperature.

Any damage to eccrine (sweat) glands within the skin can impair sweating response and potentially increase the risk of overheating if the damage covers a large enough body surface area."

Scott L. Davis, Physiologist, Southern Methodist University

Eccrine sweat glands, which are found in most skin across the body, produce sweat to cool the body. The human body must regulate its temperature for survival.

Davis, associate professor in applied physiology and wellness at SMU's Simmons School of Education and Human Development, collaborated for the study with researchers from Alma College, the University of Texas Southwestern Medical Center and the University of Kentucky College of Medicine.

In the study, they determined sweating rates in the upper and lower arms of people with tattoos by comparing at least 5.6 square centimeters of tattooed skin with adjacent non-tattooed skin. Ten people - both men and women - participated in the study.

These volunteer subjects wore a special tube-lined suit that circulated hot water in excess of 120 degrees Fahrenheit for 30 minutes to increase core temperatures and measure the level of sweating. Tattooed and non-tattooed areas of skin both began to sweat at around the same time. But tattooed areas ultimately produced less sweat than areas without tattoos.

The findings suggest that even though nerve signals to sweat glands weren't affected in tattooed skin, the sweat glands themselves were likely damaged during tattooing.

Tattoos are made permanent by injecting ink through the thin layer of outer skin into the middle layer of skin known as the dermis, which contains connective tissue, hair follicles and sweat glands. Applying a tattoo typically requires puncturing the skin with needles 50 to 3,000 times per minute, at a depth of 1-5 millimeters which could result in sweat gland damage.

"These data indicate that the collateral effects of the tattooing process negatively impact eccrine sweat gland function and could be considered a potential long-term complication or side effect of this cosmetic procedure," researchers wrote.

Source:

Journal reference:

Luetkemeier, M, J., et al. Skin tattooing impairs sweating during passive whole-body heating. Journal of Applied Physiology. doi.org/10.1152/japplphysiol.00427.2019.

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Study outlines the link between tattoos and damage to sweat glands - News-Medical.Net

Physiology

Two University of Chicago researchers elected to National Academy of Medicine – UChicago News

University of Chicago faculty members Melody Swartz and Holly J. Humphrey have been elected members of the National Academy of Medicineone of the highest honors in the field.

Swartz, the William B. Ogden Professor of Molecular Engineering at the Pritzker School of Molecular Engineering, was honored for pioneering contributions to the fields of lymphatic physiology, cancer research and immunotherapy. She holds a joint appointment in the Ben May Department for Cancer Research and is co-founder of the Chicago Immunoengineering Innovation Center.

Swartzs research focuses on gaining a deeper understanding of how the lymphatic system regulates immunity in homeostasis and disease, particularly in cancer and chronic inflammation. Her lab applies this knowledge to develop novel immunotherapeutic approaches to cancer, including lymph node-targeting vaccines. Her quantitative and interdisciplinary approach draws on bioengineering, immunobiology, physiology, cell biology and biomechanics.

Swartzs many honors include a MacArthur Fellowship (2012), as well as her election to the National Academy of Arts and Sciences (2018).

Humphrey, the Ralph W. Gerard Emeritus Professor in Medicine at the University, is currently president of the Josiah Macy Jr. Foundation. The academy honored Humphrey, MD83, for transforming medical education learning environments by creating cultures of equity, diversity, and belonging that prepare future health professionals to care for diverse populations and address social determinants of health.

Following an internal medicine residency, pulmonary and critical care fellowship, and chief residency at the University of Chicago, she served for 14 years as director of the Internal Medicine Residency Program. During her tenure as dean for medical education, her signature programs focused on equity, diversity and inclusion, mentoring, and professionalism.

She is also the chair of the Kaiser Permanente Bernard J. Tyson School of Medicines Board of Directors, chair emeritus of the American Board of Internal Medicine and of the American Board of Internal Medicine Foundation, and a past president of the Association of Program Directors in Internal Medicine.

Established originally as the Institute of Medicine in 1970 by the National Academy of Sciences, the National Academy of Medicine addresses critical issues in health, science, medicine, and related policy and inspires positive actions across sectors. Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.

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Two University of Chicago researchers elected to National Academy of Medicine - UChicago News

Physiology

KBP Biosciences Announces Data Presentation at the American Society of Nephrology Annual Meeting – GlobeNewswire

PRINCETON, N.J., Oct. 22, 2020 (GLOBE NEWSWIRE) -- KBP Biosciences Holdings Limited (KBP Biosciences), a clinical-stage biopharmaceutical company engaged in the discovery and development of innovative therapeutics for the treatment of major diseases with large underserved patient populations, today announced upcoming data to be presented at the American Society of Nephrology (ASN) Annual Meeting, being held in a virtual format from October 22-25, 2020. Frederic Jaisser, Head of the Physiology Department, Cordeliers Research Center,Research Director, INSERM, is presenting an abstract entitled: The non-steroidal mineralocorticoid receptor antagonist KBP-5074 limits albuminuria with improved efficacy and safety compared to eplerenone.

KBP-5074 is a novel, non-steroidal, highly-selective mineralocorticoid receptor antagonist (MRA) being developed for patients with hypertension and advanced chronic kidney disease (CKD). KBP Biosciences believes that the availability of an MRA that effectively decreases urinary albumin creatinine ratio (UACR) without increasing the risk of hyperkalemia would be of tremendous clinical use in the treatment of patients with heart failure (HF) and CKD, among other conditions. This pre-clinical study investigated the effect of KBP-5074 on aldosterone-mediated renal injury in the uninephrectomized SD rat CKD model. The results indicated that KBP-5074 showed a significant effect on UACR reduction, with less risk for hyperkalemia, resulting in a wider therapeutic window when compared to eplerenone. The study also showed increased urinary sodium secretion induced by KBP-5074 compared to eplerenone, which correlates with one of the expected mechanisms of action for blood pressure reduction in humans.

Dr. Jaisser said, The results of this study imply that KBP-5074 could have a wider therapeutic index than eplerenone when considering pharmacologic interventions for aldosterone receptor blockade when the risk of hyperkalemia is a concern.

Thijs Spoor, CEO of KBP Biosciences, added, We continue to be excited by the growing body of scientific evidence around the potential role of KBP-5074 in helping patients with Stage 3b/4 chronic kidney disease. We are looking forward to the final data release from our Phase 2b clinical study, which is expected to be later this year.

About KBP BiosciencesKBP Biosciences is a global, clinical-stage biopharmaceutical company engaged in the discovery and development of innovative therapeutics for the treatment of major diseases with large underserved patient populations. Headquartered in Princeton, NJ, KBP Biosciences has strong capabilities from discovery and CMC through global clinical development and registration. KBP Biosciences seeks to develop medicines in its principal therapeutic areas of organ protection and infectious diseases by focusing on novel drug candidates with well-established mechanisms of action.

KBP Biosciences lead program, KBP-5074, a novel, non-steroidal MRA, is currently completing a Phase 2b clinical study of Stage 3b/4 CKD patients with uncontrolled hypertension. KBP Biosciences is also developing KBP-7072, a potent, third-generation tetracycline, a class of antibiotics with established broad anti-infective activity against both Gram-positive and Gram-negative bacteria as well as challenging, atypical pathogens.

KBP Biosciences has built a proprietary R&D platform, which includes a compound library that is the basis of new compound discovery, a bacterium library aimed at multi-drug resistant bacteria, and an in vivo pharmacology platform for screening and testing new compounds. KBP Biosciences is actively seeking to identify additional promising therapeutic opportunities and further develop its product portfolio.

Contacts:Tyler EhlerInvestor Relationstyler.ehler@kbpbiosciences.com+1 (929) 288-9573

Investors:Lee RothBurns McClellanlroth@burnsmc.com+1 (212) 213-0006

Media: Ryo Imai / Robert Flamm, Ph.D.Burns McClellanrimai@burnsmc.com / rflamm@burnsmc.com+1 (212) 300-8315 / +1 (212) 300-8364

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KBP Biosciences Announces Data Presentation at the American Society of Nephrology Annual Meeting - GlobeNewswire

Physiology

Thought Technology Ltd. Featured on Krush Performance Podcast Series Highlighting the Role of the Brain in Peak Performance Training – Benzinga

In an ongoing series called "The Krush Brain Game", Jeff Krushell talks with leading experts and industry insiders about the role of the brain in human performance and the methods and technologies that are being used with professional and elite athletes.

MONTREAL (PRWEB) October 22, 2020

Podcaster and performance consultant, Jeff Krushell, has just released the fourth episode in his podcast series "The Krush Brain Game" in which he explores the brain body connection as it relates to optimal performance.

His belief is that, "We have come a long way in our understanding of human performance but when we look to the future, we feel, it will be new technologies and our understanding of the brain that will push human performance to new heights."

In the latest installment of the podcast, Jeff sits down with Lucas Borgo, Product Manager at Thought Technology Ltd. who is also a key figure in the development of new apps and software. The company's products have been used by Olympic and professional athletes and other high performers for decades. According to Lucas, "The use of physiological monitoring equipment can be a real game changer for both the athlete and the trainer. When you are able to see your body's physiological reaction to stress, you can more easily learn to control this reaction and be confident that the techniques you are using are having the desired effect."

Included in this ongoing series, are interviews with several influential people from the biofeedback field including: Lawrence Klein, VP and Founder of Thought Technology, Ltd.; Dr. Erik Peper, psychologist, author and president of the Biofeedback Federation of Europe; Dr. Inna Khazan who combines the use of biofeedback and mindfulness; and Dr. Leah Lagos whose focus is on HRV training for athletes and peak performers.

Click here to listen to Jeff Krushell's interview with Luke Borgo.

About Jeff Krushell

Jeff Krushell is the founder of Krush Performance and an Athlete Development Specialist & Organizational Performance Consultant. He is regarded as a noted expert in the area of talent development in sport and through his work has gained unique insights into the process of improving performance.

Over the last 25 years Jeff has worked in the world of high-performance sport helping athletes tap into their potential to truly understand what it is like to achieve Human Maximum Performance. Jeff currently consults for Major League Baseball International; CTV News, Edmonton; Vauxhall Baseball Academy; Link Management and has previously worked as the strength and conditioning coach for both the Toronto Blue Jays and Edmonton Eskimos.

About Thought Technology Ltd.

Founded in 1975, Thought Technology is the world's leading biofeedback and physiological instrument manufacturer. Its products are used as an essential part of many therapeutic treatments and clinical assessment protocols in over 85 countries and are used by tens of thousands of clinicians in thousands of medical institutions.

Always supportive of new research and development ideas, Thought Technology Ltd. has encouraged a number of special interest groups and clinicians to create cutting edge applications for its instrumentation. Thought Technology Ltd. equipment is now being used in telemedicine, web-based monitoring and biofeedback, sports training, research in human-machine interface, physiology-driven multimedia environments and virtual reality. Constantly striving to improve the quality of the products and services, TTL has obtained, and maintains, ISO 13485, and CE certification for the organization and products.

For the original version on PRWeb visit: https://www.prweb.com/releases/thought_technology_ltd_featured_on_krush_performance_podcast_series_highlighting_the_role_of_the_brain_in_peak_performance_training/prweb17494931.htm

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Thought Technology Ltd. Featured on Krush Performance Podcast Series Highlighting the Role of the Brain in Peak Performance Training - Benzinga

Physiology

How One Entomologist Takes a Multidisciplinary Approach to Bee Protection – Entomology Today

Priyadarshini Chakrabarti Basu, Ph.D., is currently a postdoctoral research associate in the Department of Horticulture at Oregon State University (OSU) and president of the OSU Postdoctoral Association. Originally from India, she earned her Ph.D. in zoology from the University of Calcutta, where she studied the effects of pesticides on wild Indian honey bees. As a result of her outstanding work, she is the recipient of the 2020 Excellence in Early Career Award by the Pacific Branch of the Entomological Society of America.

By Scott ONeal, Ph.D.

Editors Note: This is the next post in the Standout ECPs series contributed by the Entomological Society of Americas Early Career Professionals (ECP) Committee, highlighting outstanding ECPs that are doing great work in the profession. (An ECP is defined as anyone within the first five years of obtaining their terminal degree in their field.) Learn more about the work ECPs are doing within ESA, and read past posts in the Standout ECPs series.

Priyadarshini Chakrabarti Basu, Ph.D., is currently a postdoctoral research associate in the Department of Horticulture at Oregon State University (OSU) and president of the OSU Postdoctoral Association. Originally from India, she earned her Ph.D. in zoology from the University of Calcutta, where she studied the effects of pesticides on wild Indian honey bees. As a result of her outstanding work, she is the recipient of the 2020 Excellence in Early Career Award by the Pacific Branch of the Entomological Society of America. Below, we asked Chakrabarti Basu a few questions about her research and postdoc life.

ONeal: How would you describe your research program?

Chakrabarti Basu: The main goal of my research is to understand the various threats affecting bee pollinators and how best to counteract them. I study the physiological impacts of pesticides, poor nutrition, and diseases in bees, both in the field and in the lab. For each problem that is thrown at me, my research program holistically looks at it and finds ways to solve it. Along with contributing to basic sciences, I also want to be able to benefit our various stakeholders with my research findings. Throughout the years, I have collaborated with researchers, academicians, beekeepers, growers, and other non-profit and governmental agencies to help protect bee pollinators. I believe this partnership is one of the key foundations of what I do.

What makes your research program unique or sets you apart from your peers?

I am an insect physiologist working on insect nutrition, ecotoxicology, molecular ecology, insect functional biology, and insect neuroethology, with a special focus on bee pollinators. I employ multi-omics, molecular biology, and various other tools from the fields of apiculture, pollination biology, and insect physiology to address my research questions. This transdisciplinary aspect makes my research program unique.

Most importantly, one of my primary aims is to be able to translate the findings of my basic research to an applied perspective for helping our stakeholders. Crop protection and bee protection are not mutually exclusive, but it requires someone with diverse expertise and strong communication skills to bridge that gap. Consequently, I am augmenting my research program by also trying to build the first database of plant pollen nutrition in North America for both managed and native bee pollinators. Having worked across many states in India and in the UK, my diverse multicultural background also helps me to connect more easily with students and with various members of the community in the United States.

After moving to the United States from India, my postdoc mentor Dr. Ramesh Sagili and my lab mates have been incredible in providing opportunities to improve both my professional and personal growth. This has further broadened my horizon in building a research program that is multidisciplinary, unique, and highly collaborative. I cannot emphasize enough the importance of finding a great collaboratora partner who is as enthusiastic about your project as you are. At OSU, I am very lucky to have found Jeffrey Morr, who has been phenomenal in helping us to build methods for assessing pollen nutritional quality. My group of collaborators also spans across North America, Europe and Asia, and this provides me with an added opportunity to pursue novel avenues of research.

I started studying bees during my Ph.D. and I have not looked back ever since, says Priyadarshini Chakrabarti Basu, Ph.D. News about colony collapse disorder and bee declines had already reached India when I was studying in college. However, not much was really understood about bees and their troubles in the Asian subcontinent. My Ph.D. research was thus motivated by the largely overlooked question of how field-realistic pesticide exposures can affect both wild and managed honey bees.

Priyadarshini Chakrabarti Basu, Ph.D., says working with a transdisciplinary approach makes her research program unique: I am an insect physiologist working on insect nutrition, ecotoxicology, molecular ecology, insect functional biology, and insect neuroethology, with a special focus on bee pollinators. I employ multi-omics, molecular biology, and various other tools from the fields of apiculture, pollination biology, and insect physiology to address my research questions.

What is the most interesting research challenge that you have encountered, and what was your approach to solving it?

I think the most interesting challenge was to learn how to work with humans, rather than with bees. What I have come to realize is that it is all about establishing trust. Some of the larger participatory research programs that I was involved with during my Ph.D. in India required working in close cooperation with various stakeholders and marginalized sections of the community. Sampling events, surveys, fieldwork: everything was dependent on building a strong relationship with our partners, who were often spread across remote villages. Part of my success came from having the opportunity to work with a superb team, but equally as important was having an open mind, a willingness to learn, and the ability to adapt and to be kind. These things are what helped me to overcome all challenges and really feel like my work made a difference.

Another thing I must mention, however, is that we often fail to appreciate the challenges that our field sites can throw at us. At some of my Ph.D. field sites, I had to watch out for elephants and bears. In another site, there were tigers in the adjoining forests. In addition to the dangers posed by these large mammals, I was working with Apis dorsata, the giant honey bee, which builds these massive hives usually way beyond our reach. At one field-sampling event gone wrong, they stung me over 50 times! Talk about a lesson learned! Despite all of that, I restocked my first aid kit and was back to sampling the next day with a renewed enthusiasm.

Your research has been pretty exciting! Has your career been primarily focused on research?

I am also passionate about teaching and mentoring. I taught and mentored students in India and I continue to do so here at OSU. As the current President of the OSU Postdoctoral Association, I make every effort to provide mentoring opportunities to graduate students and build links between OSU postdocs and graduate students. I also regularly train and mentor students in our lab. In fact, my door is literally always open for students to walk in with their questions or problems.

COVID-19 has reshaped our teaching methods, and being an instructor for an online course at OSU this fall, I am no exception. A number of our students are studying remotely, and some of them reached out to me with their concerns about delayed textbook arrival. I agreed to scan the entire textbook for them, and the sheer joy evident in their emails was quite rewarding. Luckily, the kind folks at the OSU Valley Library did it for us, and the students now have access to it. I teach, train, and mentor graduate and undergraduate students, as I truly believe that it is important to develop scientific temper and support our next generation of entomologists, researchers and independent thinkers. In appreciation of the amazing postdoc mentor that I have at OSU, I also encourage others to be great mentors themselves.

The main goal of my research is to understand the various threats affecting bee pollinators and how best to counteract them, says Priyadarshini Chakrabarti Basu, Ph.D. I study the physiological impacts of pesticides, poor nutrition, and diseases in bees, both in the field and in the lab. For each problem that is thrown at me, my research program holistically looks at it and finds ways to solve it.

One of my primary aims is to be able to translate the findings of my basic research to an applied perspective for helping our stakeholders, says Priyadarshini Chakrabarti Basu, Ph.D. Crop protection and bee protection are not mutually exclusive, but it requires someone with diverse expertise and strong communication skills to bridge that gap.

Priyadarshini Chakrabarti Basu, Ph.D. (left), postdoctoral research associate in the Department of Horticulture at Oregon State University, spoke with Scott ONeal, Ph.D., research entomologist at Corteva Agriscience and chair of the ESA Early Career Professionals Committee for this latest installment in the committees Standout ECP series.

Why did you become an entomologist? What drew you to this field?

Insects have always fascinated me. As a child, I would spend hours in my grandmothers terrace garden, looking at bugs and wondering what are they up to on a hot summer afternoon! I have to admit, as a result of growing up in the tropics, I prefer some bugs over the others. Earning my degree in zoology gave me an overview of animal systems and the diversity that is around us. This further solidified my passion in entomology, especially learning how unique and diverse insects are.

I started studying bees during my Ph.D. and I have not looked back ever since. News about colony collapse disorder and bee declines had already reached India when I was studying in college. However, not much was really understood about bees and their troubles in the Asian subcontinent. My Ph.D. research was thus motivated by the largely overlooked question of how field-realistic pesticide exposures can affect both wild and managed honey bees. Slowly, over the years, I have expanded into researching the other stressors that affect our bees as well.

OK, so now I really want to know: Which bugs do you prefer, and why?

Of course I will choose bees! I love working with bees and I really appreciate all that bees do for us. But there are close runners-up: firefly and praying mantis. I find fireflies to be so unique, lighting up our world! I think we can all do our little bits to light up the world. And, of course, the praying mantis because it can rotate its head, unlike other insects, has great vision, and what a formidable predator!

Thank you Priya! For all of our readers, you can learn more about Dr. Chakrabarti Basus research at: http://www.priyadarshinichakrabarti.com and https://honeybeelab.oregonstate.edu/users/priyadarshini-chakrabarti-basu.

Scott ONeal, Ph.D., is a research entomologist at Corteva Agriscience and the 2019-2020 chair of the ESA Early Career Professionals Committee. Email: scott.oneal@corteva.com.

All photos courtesy of Priyadarshini Chakrabarti Basu, Ph.D.

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How One Entomologist Takes a Multidisciplinary Approach to Bee Protection - Entomology Today