Ahmed Salman,1 Amany Sholkamy,1 Mohamed Salman,2 Mahmoud Omar,1 Amr Saadawy,3 Ahmed Abdulsamad,4 Mohamed Tourky,5 Mohamed D Sarhan,2 Hossam El-Din Shaaban,6 Nesrin Abd Allah,7 Mohamed Shawkat8

1Internal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt; 2General Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt; 3Radiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt; 4Surgical Oncology, Alzahra Cancer Center, Dubai, United Arab Emirates; 5General Surgery Department, Omm Elmisrien General Hospital, Cairo, Egypt; 6Gastroenterology Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt; 7Anatomy and Embryology Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Menoufia, Egypt; 8Internal Medicine Department, Faculty of Medicine, Minia University, Minia, Egypt

Correspondence: Ahmed Salman Tel + 201000468664Email awea844@gmail.com

Background: Adult-to-adult living donor liver transplantation (LDLT) has been a common practice because of the deficiency of deceased donor liver transplants. Liver hemodynamics differ substantially between cases with end-stage liver disease undergoing LT because of various degrees of hepatic affection, nature of implicated causative factors, and pathogenesis of the hepatic disorder. The present retrospective study primarily aimed to study the early postoperative doppler changes after adult to adult LDLT. The secondary aim was to assess these hemodynamics impact on early in-hospital deaths and small for size syndrome (SFSS) development.Methods: This retrospective work was done on 123 adult cases with end-stage liver disease for whom adult LDLT was performed after exclusion of pediatric patients and those with vascular complications.Results: Postoperative (PO) mean portal vein velocity (PVV), hepatic artery (HA) peak systolic velocity (PSV), and HA resistivity index (RI) declined gradually but significantly post adult LDLT. Phasicity of hepatic veins changes towards the triphasic waveform gradually in the early PO period. There is a notable negative relationship between PO mean PVV with PO mean HA PSV. Higher PO HA RI affected PO mortality, while higher PO PVV and lower HA PSV increased the incidence of SFSS.Conclusion: Early postoperative Doppler changes post-LDLT (PO PVV, HA RI, and HA PSV) can affect both mortality and SFSS development.

Keywords: postoperative doppler, LDLT, small-for-size syndrome, mortality

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Study of Early Postoperative Doppler Changes Post Living Donor Liver T | IJGM - Dove Medical Press