10/09/2015

RESEARCH ARTICLE

New emerging pathogens are a significant threat to human health. Lisa Gralinksi and colleagues discover new animal models that better capture the range of disease found in human SARS patients and also find four novel susceptibility loci governing various aspects of SARS-induced pathogenesis.

10/09/2015

RESEARCH ARTICLE

Jingyan Liu and colleagues identify and characterize ibr5-7, a mutant that suppresses the chilling-induced defense responses of chs3-1. They observe that the enhanced defense responses and cell death in the chs3-1 mutant are synergistically dependent on IBR5 and HSP90.

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PLOS Genetics: A Peer-Reviewed Open-Access Journal