Wound healing, infection can be determined by genetics – Times of India

TEXAS: Researchers from Texas Tech's Department of Biological Sciences and Natural Science Research Laboratory recently determined that some genes have an association with the pathogens that infect chronic wounds and hinder the healing process.

In a first-of-its-kind study, researchers have determined that genetics may play a role in how wounds heal. Caleb Phillips, an assistant professor at Texas Tech University and director of the Phillips Laboratory in the Department of Biological Sciences, and doctoral student Craig Tipton led the study, "Patient genetics is linked to chronic wound microbiome composition and healing," according to a study published in the open-access, peer-reviewed medical journal PLOS Pathogens.

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"We showed that there are identifiable locations in people's genome where, depending on their genotype, they tend to get infections by specific bacteria," Phillips said. "The different genomic locations identified tend to be related in terms of the types of genes they are close to and may regulate. A working hypothesis emerging from the research is that genetic differences influencing genes encoding the way our cells interact with the environment and each other are important for infection differences."

Though there is still work to be done before the research directly benefits patients, Tipton said the study is an important and promising step in that direction.

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Wound healing, infection can be determined by genetics - Times of India

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