The Department of Immunology is a basic science department within the University of Washington, School of Medicine located in Seattle.

Our mission is to advance understanding of the function of the immune system in order to enhance our ability to fight infectious disease, cancer and autoimmune disease. Basic research of all aspects of immunology is critical to this mission, as well as translational research to link our findings to the development of new therapies.

We hold diversity and inclusiveness as core values in our department and emphasize their importance throughout our research, education and practice. We strive to create a climate that fosters belonging, respect and value for all within our scientific community and the institution.

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Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism.Mao K, Baptista AP, Tamoutounour S, Zhuang L, Bouladoux N, Martins AJ, Huang Y, Gerner MY, Belkaid Y, Germain RN. Nature. 2018; 554(7691):255-259. PMID: 29364878

Dendritic cell and antigen dispersal landscapes regulate T cell immunity.Gerner MY, Casey KA, Kastenmuller W, Germain RN.The Journal of experimental medicine. 2017; 214(10):3105-3122. PMID:28847868

Adaptation of commensal proliferating Escherichia coli to the intestinal tract of young children with cystic fibrosis.Matamouros S, Hayden HS, Hager KR, Brittnacher MJ, Lachance K, Weiss EJ, Pope CE, Imhaus AF, McNally CP, Borenstein E, Hoffman LR, Miller SI. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1605-1610. doi: 10.1073/pnas.1714373115. Epub 2018 Jan 29. PMID:29378945

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM.Sci Immunol. 2018 Jan 12;3(19). pii: eaal2736. doi: 10.1126/sciimmunol.aal2736. PMID: 29330161

SuppressionofluteinizinghormoneenhancesHSCrecoveryafterhematopoieticinjury.Velardi E, Tsai JJ, Radtke S, Cooper K, Argyropoulos KV, Jae-Hung S, Young LF, Lazrak A, Smith OM, Lieberman S, Kreines F, Shono Y, Wertheimer T, Jenq RR, Hanash AM, Narayan P, Lei Z, Moore MA, Kiem HP, van den Brink MRM, Dudakov JA.Nat Med. 2018 Feb;24(2):239-246. doi: 10.1038/nm.4470. Epub 2018 Jan 8. PMID: 29309056

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